Septerna (SEPN) EBT Margin (2023 - 2025)

Septerna (SEPN) has 3 years of EBT Margin data on record, last reported at 196.33% in Q4 2025.

  • For Q4 2025, EBT Margin rose 1002085.0% year-over-year to 196.33%; the TTM value through Dec 2025 reached 20.04%, up 674525.0%, while the annual FY2025 figure was 20.17%, 674538.0% up from the prior year.
  • EBT Margin reached 196.33% in Q4 2025 per SEPN's latest filing, up from 38.02% in the prior quarter.
  • Across five years, EBT Margin topped out at 196.33% in Q4 2025 and bottomed at 33166.67% in Q3 2023.
  • Average EBT Margin over 3 years is 10460.52%, with a median of 9806.39% recorded in 2025.
  • Peak YoY movement for EBT Margin: surged 2142860bps in 2024, then plummeted -1639930bps in 2025.
  • A 3-year view of EBT Margin shows it stood at 33166.67% in 2023, then soared by 70bps to 9824.53% in 2024, then skyrocketed by 102bps to 196.33% in 2025.
  • Per Business Quant database, its latest 3 readings for EBT Margin were 196.33% in Q4 2025, 38.02% in Q3 2025, and 20872.27% in Q2 2025.