Septerna (SEPN) EBT Margin (2023 - 2026)
Septerna's quarterly EBT Margin came in at 31.32% in Q1 2026, up 977507.0% year-on-year from N/an in Q1 2025, and up 29.57% quarter-over-quarter from 44.47% in Q4 2025.
Septerna has reported EBT Margin for 4 years, with the latest figure at 31.32% in Q1 2026.
- For the quarter ending Q1 2026, EBT Margin rose 977507.0% year-over-year to 31.32%; the trailing twelve-month figure through Mar 2026 stood at 49.41% (up 808907.0% YoY), and the FY2025 full-year result was 106.35%, up 661886.0% from the prior year.
- EBT Margin for Q1 2026 stood at 31.32%, up from 44.47% in the prior quarter.
- The five-year high for EBT Margin was 38.02% in Q3 2025, with the low at 33166.67% in Q3 2023.
- Average EBT Margin over 4 years is 9981.88%, with a median of 9806.39% recorded in 2025.
- Year-over-year, EBT Margin jumped 2142860 bps in 2024 and slumped 1639930 bps in 2025.
- Tracing SEPN's EBT Margin over 4 years: stood at 15383.9% in 2023, then jumped by 36 bps to 9824.53% in 2024, then soared by 100 bps to 44.47% in 2025, then climbed by 30 bps to 31.32% in 2026.
- The last three EBT Margin figures came in at 31.32% (Q1 2026), 44.47% (Q4 2025), and 38.02% (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBT Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Quantum Biopharma | 961,148.99 Bn | 961,148.98 Bn | - | - |
| 2 | Alterity Therapeutics | 744,933.29 Bn | 744,933.26 Bn | - | - |
| 3 | Legend Biotech | 2,540.00 Bn | 2,539.71 Bn | 242.10 Mn | -6.40% |
| 4 | Nanobiotix | 2,199.85 Bn | 2,199.78 Bn | - | - |
| 5 | Akari Therapeutics | 1,635.88 Bn | 1,635.88 Bn | - | - |
| 6 | Vertex Pharmaceuticals | 111.32 Bn | 104.07 Bn | 2.59 Bn | 41.95% |
| 7 | Evaxion A | 62.56 Bn | 62.54 Bn | - | - |
| 8 | Regeneron Pharmaceuticals | 62.55 Bn | 53.79 Bn | 3.31 Bn | 23.05% |
| 9 | Alnylam Pharmaceuticals | 39.57 Bn | 36.56 Bn | 959.66 Mn | 18.99% |
| 10 | Septerna | 1.34 Bn | 1.34 Bn | - | -31.32% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -31.32% |
| Dec 31, 2025 | -44.47% |
| Sep 30, 2025 | 38.02% |
| Jun 30, 2025 | -20,872.27% |
| Mar 31, 2025 | -9,806.39% |
| Dec 31, 2024 | -9,824.53% |
| Sep 30, 2024 | -11,738.07% |
| Jun 30, 2024 | -4,472.97% |
| Mar 31, 2024 | -4,498.11% |
| Dec 31, 2023 | -15,383.90% |
| Sep 30, 2023 | -33,166.67% |