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Asset Utilization RatioAssets AverageEBIT MarginEBITDA MarginEBT MarginEnterprise ValueEquity AverageEquity RatioFCF MarginInvested CapitalNet MarginOperating MarginReturn on AssetsReturn on Capital EmployedReturn on EquityReturn on Invested CapitalReturn on Sales

Septerna (SEPN) EBITDA Margin (2023 - 2025)

Septerna (SEPN) has 3 years of EBITDA Margin data on record, last reported at 174.19% in Q4 2025.

  • For Q4 2025, EBITDA Margin rose 1183363.0% year-over-year to 174.19%; the TTM value through Dec 2025 reached 9.12%, up 704837.0%, while the annual FY2025 figure was 22.33%, 749609.0% up from the prior year.
  • EBITDA Margin reached 174.19% in Q4 2025 per SEPN's latest filing, up from 38.95% in the prior quarter.
  • Across five years, EBITDA Margin topped out at 174.19% in Q4 2025 and bottomed at 33166.67% in Q3 2023.
  • Average EBITDA Margin over 3 years is 10635.14%, with a median of 9741.55% recorded in 2025.
  • Peak YoY movement for EBITDA Margin: soared 2161042bps in 2024, then crashed -1644697bps in 2025.
  • A 3-year view of EBITDA Margin shows it stood at 33166.67% in 2023, then soared by 65bps to 11659.43% in 2024, then surged by 101bps to 174.19% in 2025.
  • Per Business Quant database, its latest 3 readings for EBITDA Margin were 174.19% in Q4 2025, 38.95% in Q3 2025, and 20890.76% in Q2 2025.