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Asset Utilization RatioAssets AverageEBIT MarginEBITDA MarginEBT MarginEnterprise ValueEquity AverageEquity RatioFCF MarginGross MarginInvested CapitalMarket CapitalizationNet MarginOperating MarginReturn on AssetsReturn on Capital EmployedReturn on EquityReturn on Invested CapitalReturn on Sales

Septerna (SEPN) EBITDA Margin: 2023-2025

Historic EBITDA Margin for Septerna (SEPN) over the last 2 years, with Sep 2025 value amounting to 38.95%.

  • Septerna's EBITDA Margin rose 1159520.00% to 38.95% in Q3 2025 from the same period last year, while for Sep 2025 it was -283.69%, marking a year-over-year increase of 141223.00%. This contributed to the annual value of -7,518.42% for FY2024, which is 889259.00% down from last year.
  • Per Septerna's latest filing, its EBITDA Margin stood at 38.95% for Q3 2025, which was up 100.19% from -20,890.76% recorded in Q2 2025.
  • In the past 5 years, Septerna's EBITDA Margin ranged from a high of 29,082.20% in Q4 2023 and a low of -33,166.67% during Q3 2023.
  • In the last 3 years, Septerna's EBITDA Margin had a median value of -9,741.55% in 2025 and averaged -7,423.14%.
  • Over the last 5 years, Septerna's EBITDA Margin had its largest YoY gain of 2,161,042bps in 2024, and its largest YoY loss of 4,074,164bps in 2024.
  • Over the past 3 years, Septerna's EBITDA Margin (Quarterly) stood at 29,082.20% in 2023, then tumbled by 4,074,164bps to -11,659.43% in 2024, then spiked by 1,159,520bps to 38.95% in 2025.
  • Its EBITDA Margin was 38.95% in Q3 2025, compared to -20,890.76% in Q2 2025 and -9,741.55% in Q1 2025.