Septerna (SEPN) EBIT Margin (2023 - 2026)
Septerna's quarterly EBIT Margin came in at 50.19% in Q1 2026, up 1178086.0% year-on-year from N/an in Q1 2025, and down 128.81% quarter-over-quarter from 174.19% in Q4 2025.
Septerna has reported EBIT Margin for 4 years, with the latest figure at 50.19% in Q1 2026.
- For the quarter ending Q1 2026, EBIT Margin rose 1178086.0% year-over-year to 50.19%; the trailing twelve-month figure through Mar 2026 stood at 3.25% (up 934235.0% YoY), and the FY2025 full-year result was 22.33%, up 749609.0% from the prior year.
- EBIT Margin for Q1 2026 stood at 50.19%, down from 174.19% in the prior quarter.
- The five-year high for EBIT Margin was 29082.2% in Q4 2023, with the low at 36484.85% in Q3 2023.
- Average EBIT Margin over 4 years is 7062.69%, with a median of 4886.44% recorded in 2024.
- Peak annual rise in EBIT Margin reached 2367235 bps in 2024, while the deepest fall reached 4074164 bps in 2024.
- Tracing SEPN's EBIT Margin over 4 years: stood at 29082.2% in 2023, then sank by 140 bps to 11659.43% in 2024, then soared by 101 bps to 174.19% in 2025, then tumbled by 129 bps to 50.19% in 2026.
- The last three EBIT Margin figures came in at 50.19% (Q1 2026), 174.19% (Q4 2025), and 12.16% (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBIT Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Quantum Biopharma | 961,148.99 Bn | 961,148.98 Bn | - | - |
| 2 | Alterity Therapeutics | 744,933.29 Bn | 744,933.26 Bn | - | - |
| 3 | Legend Biotech | 2,540.00 Bn | 2,539.71 Bn | 242.10 Mn | -6.43% |
| 4 | Nanobiotix | 2,199.85 Bn | 2,199.78 Bn | - | - |
| 5 | Akari Therapeutics | 1,635.88 Bn | 1,635.88 Bn | - | - |
| 6 | Vertex Pharmaceuticals | 111.32 Bn | 104.07 Bn | 2.59 Bn | 38.10% |
| 7 | Evaxion A | 62.56 Bn | 62.54 Bn | - | - |
| 8 | Regeneron Pharmaceuticals | 62.55 Bn | 53.79 Bn | 3.31 Bn | 17.83% |
| 9 | Alnylam Pharmaceuticals | 39.57 Bn | 36.56 Bn | 959.66 Mn | 23.02% |
| 10 | Septerna | 1.34 Bn | 1.34 Bn | - | -50.19% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -50.19% |
| Dec 31, 2025 | 174.19% |
| Sep 30, 2025 | 12.16% |
| Jun 30, 2025 | -24,351.26% |
| Mar 31, 2025 | -11,831.05% |
| Dec 31, 2024 | -11,659.43% |
| Sep 30, 2024 | -12,812.50% |
| Jun 30, 2024 | -4,882.43% |
| Mar 31, 2024 | -4,886.44% |
| Dec 31, 2023 | 29,082.20% |
| Sep 30, 2023 | -36,484.85% |