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Septerna (SEPN) Change in Cash (2023 - 2025)

Septerna has reported Change in Cash over the past 3 years, most recently at -$199.3 million for Q4 2025.

  • Quarterly results put Change in Cash at -$199.3 million for Q4 2025, down 232.89% from a year ago — trailing twelve months through Dec 2025 was -$117.5 million (down 178.47% YoY), and the annual figure for FY2025 was -$117.5 million, down 178.47%.
  • Change in Cash for Q4 2025 was -$199.3 million at Septerna, down from $130.7 million in the prior quarter.
  • Over the last five years, Change in Cash for SEPN hit a ceiling of $150.0 million in Q4 2024 and a floor of -$199.3 million in Q4 2025.
  • Median Change in Cash over the past 3 years was -$10.0 million (2023), compared with a mean of $2.5 million.
  • Biggest five-year swings in Change in Cash: skyrocketed 1594.16% in 2024 and later crashed 294.11% in 2025.
  • Septerna's Change in Cash stood at -$10.0 million in 2023, then skyrocketed by 1594.16% to $150.0 million in 2024, then tumbled by 232.89% to -$199.3 million in 2025.
  • The last three reported values for Change in Cash were -$199.3 million (Q4 2025), $130.7 million (Q3 2025), and -$20.7 million (Q2 2025) per Business Quant data.