Septerna (SEPN) Change in Cash (2023 - 2026)

Septerna's Change in Cash history runs 4 years deep, the most recent figure standing at -$49.1 million for Q1 2026.

• In Q1 2026, Change in Cash fell 74.48% year-over-year to -$49.1 million; the TTM figure through Mar 2026 stood at -$138.4 million (down 207.56% YoY), while the FY2025 annual figure was -$117.5 million, down 178.47% from the prior year.
• Change in Cash was -$49.1 million for Q1 2026 at Septerna, up from -$199.3 million in the prior quarter.
• In the past five years, Change in Cash ranged from a high of $150.0 million in Q4 2024 to a low of -$199.3 million in Q4 2025.
• Historically, Change in Cash has averaged -$2.7 million across 4 years, with a median of -$15.4 million in 2023.
• The sharpest annual moves came in 2024 and 2025: Change in Cash surged 1594.16% in 2024, then sank 294.11% in 2025.
• A 4-year view of Change in Cash shows it stood at -$10.0 million in 2023, then soared by 1594.16% to $150.0 million in 2024, then tumbled by 232.89% to -$199.3 million in 2025, then surged by 75.35% to -$49.1 million in 2026.
• The last three Change in Cash figures came in at -$49.1 million (Q1 2026), -$199.3 million (Q4 2025), and $130.7 million (Q3 2025), per Business Quant data.