Septerna (SEPN) Cash from Operations (2023 - 2026)

Septerna's quarterly Cash from Operations came in at 25633000.0 in Q1 2026, down 9.81% year-on-year from 28421180.78 in Q1 2025, and down 71.02% quarter-over-quarter from 14988000.0 in Q4 2025.

Septerna has reported Cash from Operations for 4 years, with the latest figure at 25633000.0 in Q1 2026.

  • For the quarter ending Q1 2026, Cash from Operations fell 9.81% year-over-year to 25633000.0; the trailing twelve-month figure through Mar 2026 stood at 107899000.0 (up 245.61% YoY), and the FY2025 full-year result was 110189000.0, up 263.32% from the prior year.
  • Cash from Operations for Q1 2026 stood at 25633000.0, down from 14988000.0 in the prior quarter.
  • The five-year high for Cash from Operations was 168807000.0 in Q3 2025, with the low at 25633000.0 in Q1 2026.
  • Average Cash from Operations over 4 years is 828900.0, with a median of 16762500.0 recorded in 2024.
  • Year-over-year, Cash from Operations sank 138.24% in 2024 and surged 1103.97% in 2025.
  • Tracing SEPN's Cash from Operations over 4 years: stood at 8797000.0 in 2023, then plunged by 138.24% to 20958000.0 in 2024, then rose by 28.49% to 14988000.0 in 2025, then slumped by 71.02% to 25633000.0 in 2026.
  • The last three Cash from Operations figures came in at 25633000.0 (Q1 2026), 14988000.0 (Q4 2025), and 168807000.0 (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Cash from Operations (Qtr)
1 Quantum Biopharma 961,148.99 Bn 961,148.98 Bn - -1.67 Mn
2 Alterity Therapeutics 744,933.29 Bn 744,933.26 Bn - -
3 Legend Biotech 2,540.00 Bn 2,539.71 Bn 242.10 Mn -12.20 Mn
4 Nanobiotix 2,199.85 Bn 2,199.78 Bn - -
5 Akari Therapeutics 1,635.88 Bn 1,635.88 Bn - -2.49 Mn
6 Vertex Pharmaceuticals 111.32 Bn 104.07 Bn 2.59 Bn 1.43 Bn
7 Evaxion A 62.56 Bn 62.54 Bn - -
8 Regeneron Pharmaceuticals 62.55 Bn 53.79 Bn 3.31 Bn 1.08 Bn
9 Alnylam Pharmaceuticals 39.57 Bn 36.56 Bn 959.66 Mn 70.50 Mn
10 Septerna 1.34 Bn 1.34 Bn - -25.63 Mn

Historic Data

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DateValue
Mar 31, 2026 -25.63 Mn
Mar 31, 2026 -25.63 Mn
Dec 31, 2025 -14.99 Mn
Dec 31, 2025 -14.99 Mn
Sep 30, 2025 168.81 Mn
Sep 30, 2025 168.81 Mn
Jun 30, 2025 -20.29 Mn
Jun 30, 2025 -20.29 Mn
Mar 31, 2025 -23.34 Mn
Mar 31, 2025 -23.34 Mn
Dec 31, 2024 -20.96 Mn
Dec 31, 2024 -20.96 Mn
Sep 30, 2024 -16.81 Mn
Sep 30, 2024 -16.81 Mn
Jun 30, 2024 -12.99 Mn
Jun 30, 2024 -12.99 Mn
Mar 31, 2024 -16.71 Mn
Mar 31, 2024 -16.71 Mn
Dec 31, 2023 -8.80 Mn
Dec 31, 2023 -8.80 Mn