Septerna (SEPN) Cash from Operations (2023 - 2026)

Septerna (SEPN) recorded quarterly Cash from Operations of 25633000.0 in Q1 2026, down 71.02% quarter-over-quarter from 14988000.0 in Q4 2025, and down 9.81% on a YoY basis from 28421180.78 in Q1 2025.

Septerna (SEPN) Cash from Operations (2023 - 2026) Analysis & Trends

Septerna's Cash from Operations history runs 4 years deep, the most recent figure standing at 25633000.0 for Q1 2026.

  • In Q1 2026, Cash from Operations fell 9.81% year-over-year to 25633000.0; the TTM figure through Mar 2026 stood at 107899000.0 (up 245.61% YoY), while the FY2025 annual figure was 110189000.0, up 263.32% from the prior year.
  • Cash from Operations was 25633000.0 for Q1 2026 at Septerna, down from 14988000.0 in the prior quarter.
  • In the past five years, Cash from Operations ranged from a high of 168807000.0 in Q3 2025 to a low of 25633000.0 in Q1 2026.
  • Historically, Cash from Operations has averaged 828900.0 across 4 years, with a median of 16762500.0 in 2024.
  • The sharpest annual moves came in 2024 and 2025: Cash from Operations sank 138.24% in 2024, then soared 1103.97% in 2025.
  • A 4-year view of Cash from Operations shows it stood at 8797000.0 in 2023, then sank by 138.24% to 20958000.0 in 2024, then increased by 28.49% to 14988000.0 in 2025, then tumbled by 71.02% to 25633000.0 in 2026.
  • The last three Cash from Operations figures came in at 25633000.0 (Q1 2026), 14988000.0 (Q4 2025), and 168807000.0 (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Cash from Ops. (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -1.67 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -12.20 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -2.49 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 1.43 Bn
9 Abivax 91.96 Bn 91.96 Bn - -
10 Septerna 1.62 Bn 1.62 Bn - -25.63 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -25.63 Mn
Mar 31, 2026 -25.63 Mn
Dec 31, 2025 -14.99 Mn
Dec 31, 2025 -14.99 Mn
Sep 30, 2025 168.81 Mn
Sep 30, 2025 168.81 Mn
Jun 30, 2025 -20.29 Mn
Jun 30, 2025 -20.29 Mn
Mar 31, 2025 -23.34 Mn
Mar 31, 2025 -23.34 Mn
Dec 31, 2024 -20.96 Mn
Dec 31, 2024 -20.96 Mn
Sep 30, 2024 -16.81 Mn
Sep 30, 2024 -16.81 Mn
Jun 30, 2024 -12.99 Mn
Jun 30, 2024 -12.99 Mn
Mar 31, 2024 -16.71 Mn
Mar 31, 2024 -16.71 Mn
Dec 31, 2023 -8.80 Mn
Dec 31, 2023 -8.80 Mn