Septerna (SEPN) Cash from Investing Activities (2023 - 2026)

Septerna (SEPN) recorded quarterly Cash from Investing Activities of -$23.8 million in Q1 2026, up 87.15% quarter-over-quarter from -$185.3 million in Q4 2025, and down 388.65% on a YoY basis from $8.3 million in Q1 2025.

Septerna (SEPN) Cash from Investing Activities (2023 - 2026) Analysis & Trends

Septerna's Cash from Investing Activities history runs 4 years deep, the most recent figure standing at -$23.8 million for Q1 2026.

  • In Q1 2026, Cash from Investing Activities fell 388.65% year-over-year to -$23.8 million; the TTM figure through Mar 2026 stood at -$248.3 million (down 41.85% YoY), while the FY2025 annual figure was -$229.4 million, down 42.81% from the prior year.
  • Cash from Investing Activities was -$23.8 million for Q1 2026 at Septerna, up from -$185.3 million in the prior quarter.
  • In the past five years, Cash from Investing Activities ranged from a high of $9.6 million in Q1 2024 to a low of -$185.3 million in Q4 2025.
  • Historically, Cash from Investing Activities has averaged -$41.5 million across 4 years, with a median of -$18.0 million in 2024.
  • The sharpest annual moves came in 2024 and 2025: Cash from Investing Activities sank 10653.75% in 2024, then jumped 93.52% in 2025.
  • A 4-year view of Cash from Investing Activities shows it stood at -$1.2 million in 2023, then tumbled by 10653.75% to -$133.2 million in 2024, then sank by 39.07% to -$185.3 million in 2025, then surged by 87.15% to -$23.8 million in 2026.
  • The last three Cash from Investing Activities figures came in at -$23.8 million (Q1 2026), -$185.3 million (Q4 2025), and -$38.4 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Cash from Investing Activities (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -2.89 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn 638.50 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn -431.90 Mn
9 Abivax 91.96 Bn 91.96 Bn - 579,519.10
10 Septerna 1.62 Bn 1.62 Bn - -23.82 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -23.82 Mn
Mar 31, 2026 -23.82 Mn
Dec 31, 2025 -185.30 Mn
Dec 31, 2025 -185.30 Mn
Sep 30, 2025 -38.39 Mn
Sep 30, 2025 -38.39 Mn
Jun 30, 2025 -786,000.00
Jun 30, 2025 -786,000.00
Mar 31, 2025 -4.87 Mn
Mar 31, 2025 -4.87 Mn
Dec 31, 2024 -133.24 Mn
Dec 31, 2024 -133.24 Mn
Sep 30, 2024 -24.79 Mn
Sep 30, 2024 -24.79 Mn
Jun 30, 2024 -12.13 Mn
Jun 30, 2024 -12.13 Mn
Mar 31, 2024 9.57 Mn
Mar 31, 2024 9.57 Mn
Dec 31, 2023 -1.24 Mn
Dec 31, 2023 -1.24 Mn