KPIs & Operating Metrics(New)
Growth Metrics

Schrodinger (SDGR) Gross Margin (2019 - 2025)

Schrodinger (SDGR) has disclosed Gross Margin for 7 consecutive years, with 65.68% as the latest value for Q4 2025.

  • On a quarterly basis, Gross Margin fell 694.0% to 65.68% in Q4 2025 year-over-year; TTM through Dec 2025 was 55.74%, a 791.0% decrease, with the full-year FY2025 number at 55.74%, down 791.0% from a year prior.
  • Gross Margin was 65.68% for Q4 2025 at Schrodinger, up from 51.61% in the prior quarter.
  • In the past five years, Gross Margin ranged from a high of 77.64% in Q4 2023 to a low of 37.24% in Q3 2021.
  • A 5-year average of 55.12% and a median of 51.94% in 2025 define the central range for Gross Margin.
  • Peak YoY movement for Gross Margin: crashed -2196bps in 2021, then surged 2695bps in 2024.
  • Schrodinger's Gross Margin stood at 57.1% in 2021, then rose by 19bps to 68.09% in 2022, then grew by 14bps to 77.64% in 2023, then decreased by -6bps to 72.61% in 2024, then dropped by -10bps to 65.68% in 2025.
  • Per Business Quant, the three most recent readings for SDGR's Gross Margin are 65.68% (Q4 2025), 51.61% (Q3 2025), and 47.77% (Q2 2025).