KPIs & Operating Metrics(New)
Growth Metrics

Schrodinger (SDGR) Gross Margin (2019 - 2025)

Schrodinger has reported Gross Margin over the past 7 years, most recently at 65.68% for Q4 2025.

  • Quarterly results put Gross Margin at 65.68% for Q4 2025, down 694.0% from a year ago — trailing twelve months through Dec 2025 was 55.74% (down 791.0% YoY), and the annual figure for FY2025 was 55.74%, down 791.0%.
  • Gross Margin for Q4 2025 was 65.68% at Schrodinger, up from 51.61% in the prior quarter.
  • Over the last five years, Gross Margin for SDGR hit a ceiling of 77.64% in Q4 2023 and a floor of 37.24% in Q3 2021.
  • Median Gross Margin over the past 5 years was 51.94% (2025), compared with a mean of 55.12%.
  • Biggest five-year swings in Gross Margin: crashed -2196bps in 2021 and later surged 2695bps in 2024.
  • Schrodinger's Gross Margin stood at 57.1% in 2021, then increased by 19bps to 68.09% in 2022, then rose by 14bps to 77.64% in 2023, then dropped by -6bps to 72.61% in 2024, then fell by -10bps to 65.68% in 2025.
  • The last three reported values for Gross Margin were 65.68% (Q4 2025), 51.61% (Q3 2025), and 47.77% (Q2 2025) per Business Quant data.