Scilex Holding (SCLX) Gross Margin (2022 - 2026)
Scilex Holding (SCLX) posted quarterly Gross Margin of 48.29% for Q1 2026, down 2403.0% year-over-year from 2.1% in Q1 2025, and up 5.0% quarter-over-quarter from 45.99% in Q4 2025.
Scilex Holding (SCLX) Gross Margin (2022 - 2026) Analysis & Trends
Scilex Holding's Gross Margin history runs 5 years deep, the most recent figure standing at 48.29% for Q1 2026.
- In Q1 2026, Gross Margin fell 2403.0% year-over-year to 48.29%; the TTM figure through Mar 2026 stood at 59.69% (down 1224.0% YoY), while the FY2025 annual figure was 65.02%, down 549.0% from the prior year.
- Gross Margin for Q1 2026 stood at 48.29%, up from 45.99% in the prior quarter.
- The five-year high for Gross Margin was 83.21% in Q1 2022, with the low at 45.99% in Q4 2025.
- The 5-year median for Gross Margin is 66.94% (2025), against an average of 67.2%.
- The sharpest annual moves came in 2025 and 2026: Gross Margin soared 760 bps in 2025, then tumbled 2403 bps in 2026.
- Scilex Holding's Gross Margin stood at 62.14% in 2022, then climbed by 7 bps to 66.42% in 2023, then grew by 3 bps to 68.54% in 2024, then sank by 33 bps to 45.99% in 2025, then gained by 5 bps to 48.29% in 2026.
- Business Quant data shows SCLX's Gross Margin at 48.29% in Q1 2026, 45.99% in Q4 2025, and 68.48% in Q3 2025.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Gross Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 653.37 Bn | 632.61 Bn | 17.26 Bn | 68.19% |
| 2 | AbbVie | 469.65 Bn | 463.08 Bn | 12.70 Bn | 74.74% |
| 3 | Merck | 376.13 Bn | 368.99 Bn | 12.21 Bn | 73.54% |
| 4 | Novartis Ag | 303.28 Bn | 295.59 Bn | 11.24 Bn | 78.02% |
| 5 | Astrazeneca | 258.06 Bn | 253.16 Bn | 12.86 Bn | 83.60% |
| 6 | Amgen | 236.35 Bn | 222.36 Bn | 7.24 Bn | 72.04% |
| 7 | Gilead Sciences | 182.15 Bn | 178.97 Bn | 6.22 Bn | 79.76% |
| 8 | Pfizer | 159.57 Bn | 147.87 Bn | 10.94 Bn | 72.78% |
| 9 | Gsk | 106.24 Bn | 102.07 Bn | 8.24 Bn | 73.05% |
| 10 | Scilex Holding | 39.10 Mn | -73.69 Mn | 3.97 Mn | 51.88% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 48.29% |
| Dec 31, 2025 | 45.99% |
| Sep 30, 2025 | 68.48% |
| Jun 30, 2025 | 66.94% |
| Mar 31, 2025 | 72.32% |
| Dec 31, 2024 | 68.54% |
| Sep 30, 2024 | 73.90% |
| Jun 30, 2024 | 73.18% |
| Mar 31, 2024 | 64.72% |
| Dec 31, 2023 | 66.42% |
| Sep 30, 2023 | 66.47% |
| Jun 30, 2023 | 66.80% |
| Mar 31, 2023 | 66.07% |
| Dec 31, 2022 | 62.14% |
| Sep 30, 2022 | 68.26% |
| Jun 30, 2022 | 80.71% |
| Mar 31, 2022 | 83.21% |