Scilex Holding (SCLX) Gross Margin (2022 - 2026)

Scilex Holding (SCLX) posted quarterly Gross Margin of 48.29% for Q1 2026, down 2403.0% year-over-year from 2.1% in Q1 2025, and up 5.0% on a QoQ basis from 45.99% in Q4 2025.

Scilex Holding (SCLX) Gross Margin (2022 - 2026) Analysis & Trends

Scilex Holding (SCLX) has reported Gross Margin for 5 consecutive years, with 48.29% the latest figure, recorded in Q1 2026.

  • In Q1 2026, Gross Margin fell 2403.0% year-over-year to 48.29%; the TTM figure through Mar 2026 stood at 59.69% (down 1224.0% YoY), while the FY2025 annual figure was 65.02%, down 549.0% from the prior year.
  • Gross Margin came in at 48.29% for Q1 2026 at Scilex Holding, up from 45.99% in the prior quarter.
  • The five-year high for Gross Margin was 83.21% in Q1 2022, with the low at 45.99% in Q4 2025.
  • Average Gross Margin over 5 years is 67.2%, with a median of 66.94% recorded in 2025.
  • Across the five-year window, Gross Margin jumped 760 bps in 2025 and sank 2403 bps in 2026, its largest moves.
  • Year by year, Gross Margin stood at 62.14% in 2022, then gained by 7 bps to 66.42% in 2023, then rose by 3 bps to 68.52% in 2024, then slumped by 33 bps to 45.99% in 2025, then increased by 5 bps to 48.29% in 2026.
  • According to Business Quant data, Gross Margin over the past three periods registered 48.29%, 45.99%, and 68.48% for Q1 2026, Q4 2025, and Q3 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Gross Margin (Qtr)
1 Eli Lilly 1,066.16 Bn 1,060.88 Bn 16.22 Bn 81.93%
2 Johnson & Johnson 611.69 Bn 589.64 Bn 15.96 Bn 66.31%
3 AbbVie 444.34 Bn 434.99 Bn 10.78 Bn 71.88%
4 Astrazeneca 284.94 Bn 277.05 Bn 12.61 Bn 87.65%
5 Merck 224.23 Bn 218.58 Bn 12.09 Bn 74.24%
6 Amgen 195.12 Bn 183.08 Bn 5.87 Bn 68.16%
7 Gilead Sciences 156.45 Bn 148.73 Bn 5.52 Bn 79.24%
8 Pfizer 136.01 Bn 123.24 Bn -1.21 Bn -51.69%
9 Novartis Ag 113.45 Bn 113.67 Bn - -
10 Scilex Holding 54.30 Mn -95.62 Mn 4.15 Mn 48.29%

Historic Data

Download Data
DateValue
Mar 31, 2026 48.29%
Dec 31, 2025 45.99%
Sep 30, 2025 68.48%
Jun 30, 2025 66.94%
Mar 31, 2025 72.32%
Dec 31, 2024 68.52%
Sep 30, 2024 73.90%
Jun 30, 2024 73.18%
Mar 31, 2024 64.72%
Dec 31, 2023 66.42%
Sep 30, 2023 66.47%
Jun 30, 2023 66.80%
Mar 31, 2023 66.07%
Dec 31, 2022 62.14%
Sep 30, 2022 68.26%
Jun 30, 2022 80.71%
Mar 31, 2022 83.21%