Scilex Holding (SCLX) Gross Margin (2022 - 2026)
Scilex Holding (SCLX) posted quarterly Gross Margin of 48.29% for Q1 2026, down 2403.0% year-over-year from 2.1% in Q1 2025, and up 5.0% on a QoQ basis from 45.99% in Q4 2025.
Scilex Holding (SCLX) Gross Margin (2022 - 2026) Analysis & Trends
Scilex Holding (SCLX) has reported Gross Margin for 5 consecutive years, with 48.29% the latest figure, recorded in Q1 2026.
- In Q1 2026, Gross Margin fell 2403.0% year-over-year to 48.29%; the TTM figure through Mar 2026 stood at 59.69% (down 1224.0% YoY), while the FY2025 annual figure was 65.02%, down 549.0% from the prior year.
- Gross Margin came in at 48.29% for Q1 2026 at Scilex Holding, up from 45.99% in the prior quarter.
- The five-year high for Gross Margin was 83.21% in Q1 2022, with the low at 45.99% in Q4 2025.
- Average Gross Margin over 5 years is 67.2%, with a median of 66.94% recorded in 2025.
- Across the five-year window, Gross Margin jumped 760 bps in 2025 and sank 2403 bps in 2026, its largest moves.
- Year by year, Gross Margin stood at 62.14% in 2022, then gained by 7 bps to 66.42% in 2023, then rose by 3 bps to 68.52% in 2024, then slumped by 33 bps to 45.99% in 2025, then increased by 5 bps to 48.29% in 2026.
- According to Business Quant data, Gross Margin over the past three periods registered 48.29%, 45.99%, and 68.48% for Q1 2026, Q4 2025, and Q3 2025 respectively.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Gross Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,066.16 Bn | 1,060.88 Bn | 16.22 Bn | 81.93% |
| 2 | Johnson & Johnson | 611.69 Bn | 589.64 Bn | 15.96 Bn | 66.31% |
| 3 | AbbVie | 444.34 Bn | 434.99 Bn | 10.78 Bn | 71.88% |
| 4 | Astrazeneca | 284.94 Bn | 277.05 Bn | 12.61 Bn | 87.65% |
| 5 | Merck | 224.23 Bn | 218.58 Bn | 12.09 Bn | 74.24% |
| 6 | Amgen | 195.12 Bn | 183.08 Bn | 5.87 Bn | 68.16% |
| 7 | Gilead Sciences | 156.45 Bn | 148.73 Bn | 5.52 Bn | 79.24% |
| 8 | Pfizer | 136.01 Bn | 123.24 Bn | -1.21 Bn | -51.69% |
| 9 | Novartis Ag | 113.45 Bn | 113.67 Bn | - | - |
| 10 | Scilex Holding | 54.30 Mn | -95.62 Mn | 4.15 Mn | 48.29% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 48.29% |
| Dec 31, 2025 | 45.99% |
| Sep 30, 2025 | 68.48% |
| Jun 30, 2025 | 66.94% |
| Mar 31, 2025 | 72.32% |
| Dec 31, 2024 | 68.52% |
| Sep 30, 2024 | 73.90% |
| Jun 30, 2024 | 73.18% |
| Mar 31, 2024 | 64.72% |
| Dec 31, 2023 | 66.42% |
| Sep 30, 2023 | 66.47% |
| Jun 30, 2023 | 66.80% |
| Mar 31, 2023 | 66.07% |
| Dec 31, 2022 | 62.14% |
| Sep 30, 2022 | 68.26% |
| Jun 30, 2022 | 80.71% |
| Mar 31, 2022 | 83.21% |