Growth Metrics

Scilex Holding (SCLX) Gross Margin (2022 - 2025)

Scilex Holding has reported Gross Margin over the past 4 years, most recently at 45.46% for Q4 2025.

  • For Q4 2025, Gross Margin fell 2308.0% year-over-year to 45.46%; the TTM value through Dec 2025 reached 64.97%, down 555.0%, while the annual FY2025 figure was 64.97%, 555.0% down from the prior year.
  • Gross Margin for Q4 2025 was 45.46% at Scilex Holding, down from 68.48% in the prior quarter.
  • Over five years, Gross Margin peaked at 83.21% in Q1 2022 and troughed at 45.46% in Q4 2025.
  • A 4-year average of 68.35% and a median of 67.6% in 2022 define the central range for Gross Margin.
  • On a YoY basis, Gross Margin climbed as much as 762bps in 2025 and fell as far as -2308bps in 2025.
  • Year by year, Gross Margin stood at 62.14% in 2022, then rose by 7bps to 66.42% in 2023, then grew by 3bps to 68.54% in 2024, then tumbled by -34bps to 45.46% in 2025.
  • Business Quant data shows Gross Margin for SCLX at 45.46% in Q4 2025, 68.48% in Q3 2025, and 66.94% in Q2 2025.