Rhythm Pharmaceuticals (RYTM) Operating Income (2016 - 2026)
Rhythm Pharmaceuticals (RYTM) reported Operating Income of -$52.4 million for Q1 2026, down 11.4% year-over-year from -$59.1 million in Q1 2025, and down 11.26% quarter-over-quarter from -$47.1 million in Q4 2025.
Rhythm Pharmaceuticals (RYTM) Operating Income (2016 - 2026) Analysis & Trends
Rhythm Pharmaceuticals (RYTM) has 11 years of Operating Income data on file, last reported at -$52.4 million in Q1 2026.
- Operating Income for Q1 2026 came in at -$52.4 million, down 11.4% year-over-year; the trailing twelve-month figure through Mar 2026 was -$197.4 million (down 14.34% YoY), and the FY2025 annual result was -$192.0 million, up 27.68% from the prior year.
- Operating Income slipped to -$52.4 million in Q1 2026 per RYTM's latest filing, from -$47.1 million in the prior quarter.
- Over five years, Operating Income peaked at -$39.3 million in Q3 2022 and troughed at -$139.9 million in Q1 2024.
- A 5-year average of -$51.4 million and a median of -$45.3 million in 2025 frame the typical range for Operating Income.
- The sharpest annual moves came in 2024 and 2025: Operating Income tumbled 166.29% in 2024, then surged 66.4% in 2025.
- A 5-year view of Operating Income shows it stood at -$42.1 million in 2022, then grew by 1.99% to -$41.3 million in 2023, then increased by 0.02% to -$41.3 million in 2024, then slipped by 14.08% to -$47.1 million in 2025, then slipped by 11.26% to -$52.4 million in 2026.
- Business Quant data shows RYTM's Operating Income at -$52.4 million in Q1 2026, -$47.1 million in Q4 2025, and -$52.7 million in Q3 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Op. Inc (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | -32.68 Mn |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | -2.97 Mn |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | -19.70 Mn |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | -3.82 Mn |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | -15.76 Mn |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 1.14 Bn |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | -65.83 Mn |
| 10 | Rhythm Pharmaceuticals | 6.59 Bn | 6.25 Bn | 52.96 Mn | -52.36 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -52.36 Mn |
| Dec 31, 2025 | -47.06 Mn |
| Sep 30, 2025 | -52.65 Mn |
| Jun 30, 2025 | -45.30 Mn |
| Mar 31, 2025 | -47.00 Mn |
| Dec 31, 2024 | -41.26 Mn |
| Sep 30, 2024 | -43.89 Mn |
| Jun 30, 2024 | -40.48 Mn |
| Mar 31, 2024 | -139.89 Mn |
| Dec 31, 2023 | -41.27 Mn |
| Sep 30, 2023 | -43.95 Mn |
| Jun 30, 2023 | -46.60 Mn |
| Mar 31, 2023 | -52.53 Mn |
| Dec 31, 2022 | -42.10 Mn |
| Sep 30, 2022 | -39.27 Mn |
| Jun 30, 2022 | -45.10 Mn |
| Mar 31, 2022 | -52.69 Mn |
| Dec 31, 2021 | -50.99 Mn |
| Sep 30, 2021 | -44.24 Mn |
| Jun 30, 2021 | -40.43 Mn |