Rhythm Pharmaceuticals (RYTM) Net Margin (2021 - 2026)
Rhythm Pharmaceuticals' (RYTM) quarterly Net Margin came in at 94.4% in Q1 2026, up 6100.0% year-on-year from 1.52% in Q1 2025, and down 10.66% on a QoQ basis from 85.3% in Q4 2025.
Rhythm Pharmaceuticals (RYTM) Net Margin (2021 - 2026) Analysis & Trends
Rhythm Pharmaceuticals (RYTM) has 6 years of Net Margin data on file, last reported at 94.4% in Q1 2026.
- On a quarterly basis, Net Margin rose 6100.0% year-over-year to 94.4% in Q1 2026; TTM through Mar 2026 was 95.71%, a 3142.0% increase from a year earlier, with the FY2025 full-year figure at 106.41%, up 9691.0% from the prior year.
- Net Margin for Q1 2026 stood at 94.4%, down from 85.3% in the prior quarter.
- Over the last five years, Net Margin for RYTM reached as high as 527.99% in Q4 2022 and fell as low as 3693.79% in Q1 2022.
- Historically, Net Margin has averaged 420.6% across 5 years, with a median of 155.39% in 2025.
- On a YoY basis, Net Margin climbed as much as 1239263 bps in 2022 and fell as far as 12869379 bps in 2022.
- Year by year, Net Margin stood at 527.99% in 2022, then plunged by 133 bps to 171.8% in 2023, then surged by 38 bps to 106.7% in 2024, then increased by 20 bps to 85.3% in 2025, then declined by 11 bps to 94.4% in 2026.
- Per Business Quant data, the three most recent Net Margin figures were 94.4% in Q1 2026, 85.3% in Q4 2025, and 105.81% in Q3 2025.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 68,785.72 Bn | 68,785.72 Bn | - | - |
| 2 | Nanobiotix | 1,895.57 Bn | 1,895.51 Bn | - | - |
| 3 | BeOne Medicines | 471.35 Bn | 466.56 Bn | 1.35 Bn | 15.02% |
| 4 | NuCana | 279.75 Bn | 279.75 Bn | - | - |
| 5 | Vertex Pharmaceuticals | 120.24 Bn | 113.00 Bn | 2.59 Bn | 34.53% |
| 6 | Regeneron Pharmaceuticals | 67.80 Bn | 59.04 Bn | 3.31 Bn | 20.17% |
| 7 | Belite Bio | 62.51 Bn | 62.51 Bn | - | - |
| 8 | Argenx Se | 57.38 Bn | 57.38 Bn | 1.41 Bn | 30.33% |
| 9 | Revolution Medicines | 37.78 Bn | 37.78 Bn | - | - |
| 10 | Rhythm Pharmaceuticals | 6.98 Bn | 6.64 Bn | 52.96 Mn | -94.40% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -94.40% |
| Dec 31, 2025 | -85.30% |
| Sep 30, 2025 | -105.81% |
| Jun 30, 2025 | -98.93% |
| Mar 31, 2025 | -155.39% |
| Dec 31, 2024 | -106.70% |
| Sep 30, 2024 | -135.24% |
| Jun 30, 2024 | -115.42% |
| Mar 31, 2024 | -544.43% |
| Dec 31, 2023 | -171.80% |
| Sep 30, 2023 | -196.25% |
| Jun 30, 2023 | -242.98% |
| Mar 31, 2023 | -454.96% |
| Dec 31, 2022 | 527.99% |
| Sep 30, 2022 | -953.80% |
| Jun 30, 2022 | -523.06% |
| Mar 31, 2022 | -3,693.79% |
| Dec 31, 2021 | -2,962.63% |
| Sep 30, 2021 | -3,727.14% |
| Jun 30, 2021 | -12,915.69% |