Rhythm Pharmaceuticals (RYTM) Net Margin (2021 - 2026)
Rhythm Pharmaceuticals (RYTM) reported Net Margin of 94.4% for Q1 2026, up 6100.0% year-over-year from 1.52% in Q1 2025, and down 10.66% quarter-over-quarter from 85.3% in Q4 2025.
Rhythm Pharmaceuticals (RYTM) Net Margin (2021 - 2026) Analysis & Trends
Rhythm Pharmaceuticals (RYTM) has 6 years of Net Margin data on file, last reported at 94.4% in Q1 2026.
- Net Margin for Q1 2026 came in at 94.4%, up 6100.0% year-over-year; the trailing twelve-month figure through Mar 2026 was 95.71% (up 3142.0% YoY), and the FY2025 annual result was 106.41%, up 9691.0% from the prior year.
- Net Margin eased to 94.4% in Q1 2026 per RYTM's latest filing, from 85.3% in the prior quarter.
- Over five years, Net Margin peaked at 527.99% in Q4 2022 and troughed at 3506.74% in Q1 2022.
- A 5-year average of 407.94% and a median of 155.39% in 2025 frame the typical range for Net Margin.
- On a YoY basis, Net Margin climbed as much as 1242079 bps in 2022 and fell as far as 12850674 bps in 2022.
- A 5-year view of Net Margin shows it stood at 527.99% in 2022, then tumbled by 133 bps to 171.8% in 2023, then surged by 38 bps to 106.7% in 2024, then advanced by 20 bps to 85.3% in 2025, then decreased by 11 bps to 94.4% in 2026.
- Business Quant data shows RYTM's Net Margin at 94.4% in Q1 2026, 85.3% in Q4 2025, and 105.81% in Q3 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | - |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | 0.82% |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | - |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | - |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 34.53% |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | - |
| 10 | Rhythm Pharmaceuticals | 6.59 Bn | 6.25 Bn | 52.96 Mn | -94.40% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -94.40% |
| Dec 31, 2025 | -85.30% |
| Sep 30, 2025 | -105.81% |
| Jun 30, 2025 | -98.93% |
| Mar 31, 2025 | -155.39% |
| Dec 31, 2024 | -106.70% |
| Sep 30, 2024 | -135.24% |
| Jun 30, 2024 | -115.42% |
| Mar 31, 2024 | -544.43% |
| Dec 31, 2023 | -171.80% |
| Sep 30, 2023 | -196.25% |
| Jun 30, 2023 | -242.98% |
| Mar 31, 2023 | -454.96% |
| Dec 31, 2022 | 527.99% |
| Sep 30, 2022 | -953.80% |
| Jun 30, 2022 | -494.90% |
| Mar 31, 2022 | -3,506.74% |
| Dec 31, 2021 | -2,798.84% |
| Sep 30, 2021 | -3,415.08% |
| Jun 30, 2021 | -12,915.69% |