Rhythm Pharmaceuticals (RYTM) Net Margin (2021 - 2026)

Rhythm Pharmaceuticals' (RYTM) quarterly Net Margin came in at 94.4% in Q1 2026, up 6100.0% year-on-year from 1.52% in Q1 2025, and down 10.66% on a QoQ basis from 85.3% in Q4 2025.

Rhythm Pharmaceuticals (RYTM) Net Margin (2021 - 2026) Analysis & Trends

Rhythm Pharmaceuticals (RYTM) has 6 years of Net Margin data on file, last reported at 94.4% in Q1 2026.

  • On a quarterly basis, Net Margin rose 6100.0% year-over-year to 94.4% in Q1 2026; TTM through Mar 2026 was 95.71%, a 3142.0% increase from a year earlier, with the FY2025 full-year figure at 106.41%, up 9691.0% from the prior year.
  • Net Margin for Q1 2026 stood at 94.4%, down from 85.3% in the prior quarter.
  • Over the last five years, Net Margin for RYTM reached as high as 527.99% in Q4 2022 and fell as low as 3693.79% in Q1 2022.
  • Historically, Net Margin has averaged 420.6% across 5 years, with a median of 155.39% in 2025.
  • On a YoY basis, Net Margin climbed as much as 1239263 bps in 2022 and fell as far as 12869379 bps in 2022.
  • Year by year, Net Margin stood at 527.99% in 2022, then plunged by 133 bps to 171.8% in 2023, then surged by 38 bps to 106.7% in 2024, then increased by 20 bps to 85.3% in 2025, then declined by 11 bps to 94.4% in 2026.
  • Per Business Quant data, the three most recent Net Margin figures were 94.4% in Q1 2026, 85.3% in Q4 2025, and 105.81% in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Margin (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 15.02%
4 NuCana 279.75 Bn 279.75 Bn - -
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 34.53%
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 20.17%
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn 30.33%
9 Revolution Medicines 37.78 Bn 37.78 Bn - -
10 Rhythm Pharmaceuticals 6.98 Bn 6.64 Bn 52.96 Mn -94.40%

Historic Data

Download Data
DateValue
Mar 31, 2026 -94.40%
Dec 31, 2025 -85.30%
Sep 30, 2025 -105.81%
Jun 30, 2025 -98.93%
Mar 31, 2025 -155.39%
Dec 31, 2024 -106.70%
Sep 30, 2024 -135.24%
Jun 30, 2024 -115.42%
Mar 31, 2024 -544.43%
Dec 31, 2023 -171.80%
Sep 30, 2023 -196.25%
Jun 30, 2023 -242.98%
Mar 31, 2023 -454.96%
Dec 31, 2022 527.99%
Sep 30, 2022 -953.80%
Jun 30, 2022 -523.06%
Mar 31, 2022 -3,693.79%
Dec 31, 2021 -2,962.63%
Sep 30, 2021 -3,727.14%
Jun 30, 2021 -12,915.69%