Rhythm Pharmaceuticals (RYTM) Gross Profit (2021 - 2026)

Rhythm Pharmaceuticals (RYTM) reported Gross Profit of $53.0 million for Q1 2026, up 82.25% year-over-year from $29.1 million in Q1 2025, and up 0.96% quarter-over-quarter from $52.5 million in Q4 2025.

Rhythm Pharmaceuticals (RYTM) Gross Profit (2021 - 2026) Analysis & Trends

Rhythm Pharmaceuticals (RYTM) has 6 years of Gross Profit data on file, last reported at $53.0 million in Q1 2026.

  • Gross Profit for Q1 2026 came in at $53.0 million, up 82.25% year-over-year; the trailing twelve-month figure through Mar 2026 was $194.2 million (up 58.3% YoY), and the FY2025 annual result was $170.3 million, up 45.83% from the prior year.
  • Gross Profit advanced to $53.0 million in Q1 2026 per RYTM's latest filing, from $52.5 million in the prior quarter.
  • Over five years, Gross Profit peaked at $53.0 million in Q1 2026 and troughed at -$9.1 million in Q4 2022.
  • A 5-year average of $24.3 million and a median of $23.2 million in 2024 frame the typical range for Gross Profit.
  • On a YoY basis, Gross Profit climbed as much as 6241.61% in 2022 and fell as far as 674.07% in 2022.
  • A 5-year view of Gross Profit shows it stood at -$9.1 million in 2022, then surged by 331.39% to $21.0 million in 2023, then soared by 81.15% to $38.0 million in 2024, then jumped by 37.87% to $52.5 million in 2025, then gained by 0.96% to $53.0 million in 2026.
  • Business Quant data shows RYTM's Gross Profit at $53.0 million in Q1 2026, $52.5 million in Q4 2025, and $45.8 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn -
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn -
7 Psyence Biomedical 212.16 Bn 212.16 Bn -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn
9 Abivax 91.96 Bn 91.96 Bn -
10 Rhythm Pharmaceuticals 6.59 Bn 6.25 Bn 52.96 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 52.96 Mn
Mar 31, 2026 52.96 Mn
Dec 31, 2025 52.45 Mn
Dec 31, 2025 52.45 Mn
Sep 30, 2025 45.80 Mn
Sep 30, 2025 45.80 Mn
Jun 30, 2025 42.96 Mn
Jun 30, 2025 42.96 Mn
Mar 31, 2025 29.06 Mn
Mar 31, 2025 29.06 Mn
Dec 31, 2024 38.04 Mn
Dec 31, 2024 38.04 Mn
Sep 30, 2024 29.42 Mn
Sep 30, 2024 29.42 Mn
Jun 30, 2024 26.13 Mn
Jun 30, 2024 26.13 Mn
Mar 31, 2024 23.16 Mn
Mar 31, 2024 23.16 Mn
Dec 31, 2023 21.00 Mn
Dec 31, 2023 21.00 Mn