Rhythm Pharmaceuticals (RYTM) Gross Profit (2021 - 2026)

Rhythm Pharmaceuticals (RYTM) posted quarterly Gross Profit of $53.0 million for Q1 2026, up 82.25% year-over-year from $29.1 million in Q1 2025, and up 0.96% quarter-over-quarter from $52.5 million in Q4 2025.

Rhythm Pharmaceuticals (RYTM) Gross Profit (2021 - 2026) Analysis & Trends

Rhythm Pharmaceuticals (RYTM) has reported Gross Profit for 6 consecutive years, with $53.0 million the latest figure, recorded in Q1 2026.

  • In Q1 2026, Gross Profit rose 82.25% year-over-year to $53.0 million; the TTM figure through Mar 2026 stood at $194.2 million (up 58.3% YoY), while the FY2025 annual figure was $170.3 million, up 45.83% from the prior year.
  • Gross Profit rose to $53.0 million in Q1 2026 per RYTM's latest filing, from $52.5 million in the prior quarter.
  • Across five years, Gross Profit topped out at $53.0 million in Q1 2026 and bottomed at -$9.1 million in Q4 2022.
  • Historically, Gross Profit has averaged $24.3 million across 5 years, with a median of $23.2 million in 2024.
  • On a YoY basis, Gross Profit climbed as much as 6241.61% in 2022 and fell as far as 674.07% in 2022.
  • Rhythm Pharmaceuticals' Gross Profit stood at -$9.1 million in 2022, then soared by 331.39% to $21.0 million in 2023, then jumped by 81.15% to $38.0 million in 2024, then surged by 37.87% to $52.5 million in 2025, then advanced by 0.96% to $53.0 million in 2026.
  • Business Quant data shows RYTM's Gross Profit at $53.0 million in Q1 2026, $52.5 million in Q4 2025, and $45.8 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn
4 Revolution Medicines 43.64 Bn 43.64 Bn -
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn
7 Royalty Pharma 33.72 Bn 35.84 Bn -
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn
10 Rhythm Pharmaceuticals 7.95 Bn 7.62 Bn 62.32 Mn

Historic Data

Download Data
DateValue
Jun 30, 2026 62.32 Mn
Jun 30, 2026 62.32 Mn
Mar 31, 2026 52.96 Mn
Mar 31, 2026 52.96 Mn
Dec 31, 2025 52.45 Mn
Dec 31, 2025 52.45 Mn
Sep 30, 2025 45.80 Mn
Sep 30, 2025 45.80 Mn
Jun 30, 2025 42.96 Mn
Jun 30, 2025 42.96 Mn
Mar 31, 2025 29.06 Mn
Mar 31, 2025 29.06 Mn
Dec 31, 2024 38.04 Mn
Dec 31, 2024 38.04 Mn
Sep 30, 2024 29.42 Mn
Sep 30, 2024 29.42 Mn
Jun 30, 2024 26.13 Mn
Jun 30, 2024 26.13 Mn
Mar 31, 2024 23.16 Mn
Mar 31, 2024 23.16 Mn