Rhythm Pharmaceuticals (RYTM) Gross Profit (2021 - 2026)

Rhythm Pharmaceuticals' (RYTM) quarterly Gross Profit came in at $53.0 million in Q1 2026, up 82.25% year-on-year from $29.1 million in Q1 2025, and up 0.96% on a QoQ basis from $52.5 million in Q4 2025.

Rhythm Pharmaceuticals (RYTM) Gross Profit (2021 - 2026) Analysis & Trends

Rhythm Pharmaceuticals (RYTM) has 6 years of Gross Profit data on file, last reported at $53.0 million in Q1 2026.

  • On a quarterly basis, Gross Profit rose 82.25% year-over-year to $53.0 million in Q1 2026; TTM through Mar 2026 was $194.2 million, a 58.3% increase from a year earlier, with the FY2025 full-year figure at $170.3 million, up 45.83% from the prior year.
  • Gross Profit for Q1 2026 stood at $53.0 million, up from $52.5 million in the prior quarter.
  • Over the last five years, Gross Profit for RYTM reached as high as $53.0 million in Q1 2026 and fell as low as -$9.1 million in Q4 2022.
  • Historically, Gross Profit has averaged $24.3 million across 5 years, with a median of $23.2 million in 2024.
  • On a YoY basis, Gross Profit climbed as much as 6241.61% in 2022 and fell as far as 674.07% in 2022.
  • Year by year, Gross Profit stood at -$9.1 million in 2022, then surged by 331.39% to $21.0 million in 2023, then soared by 81.15% to $38.0 million in 2024, then jumped by 37.87% to $52.5 million in 2025, then grew by 0.96% to $53.0 million in 2026.
  • Per Business Quant data, the three most recent Gross Profit figures were $53.0 million in Q1 2026, $52.5 million in Q4 2025, and $45.8 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn -
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn -
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn
7 Belite Bio 61.40 Bn 61.40 Bn -
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn
9 Revolution Medicines 37.37 Bn 37.37 Bn -
10 Rhythm Pharmaceuticals 6.99 Bn 6.64 Bn 52.96 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 52.96 Mn
Mar 31, 2026 52.96 Mn
Dec 31, 2025 52.45 Mn
Dec 31, 2025 52.45 Mn
Sep 30, 2025 45.80 Mn
Sep 30, 2025 45.80 Mn
Jun 30, 2025 42.96 Mn
Jun 30, 2025 42.96 Mn
Mar 31, 2025 29.06 Mn
Mar 31, 2025 29.06 Mn
Dec 31, 2024 38.04 Mn
Dec 31, 2024 38.04 Mn
Sep 30, 2024 29.42 Mn
Sep 30, 2024 29.42 Mn
Jun 30, 2024 26.13 Mn
Jun 30, 2024 26.13 Mn
Mar 31, 2024 23.16 Mn
Mar 31, 2024 23.16 Mn
Dec 31, 2023 21.00 Mn
Dec 31, 2023 21.00 Mn