Rhythm Pharmaceuticals (RYTM) Free Cash Flow (2016 - 2026)

Rhythm Pharmaceuticals (RYTM) posted quarterly Free Cash Flow of -$43.8 million for Q1 2026, down 8.7% year-over-year from -$47.9 million in Q1 2025, and down 67.82% quarter-over-quarter from -$26.1 million in Q4 2025.

Rhythm Pharmaceuticals (RYTM) Free Cash Flow (2016 - 2026) Analysis & Trends

Rhythm Pharmaceuticals (RYTM) has reported Free Cash Flow for 11 consecutive years, with -$43.8 million the latest figure, recorded in Q1 2026.

  • In Q1 2026, Free Cash Flow fell 8.7% year-over-year to -$43.8 million; the TTM figure through Mar 2026 stood at -$119.6 million (down 4.36% YoY), while the FY2025 annual figure was -$116.1 million, down 1.93% from the prior year.
  • Free Cash Flow fell to -$43.8 million in Q1 2026 per RYTM's latest filing, from -$26.1 million in the prior quarter.
  • Across five years, Free Cash Flow topped out at -$17.9 million in Q2 2025 and bottomed at -$53.8 million in Q1 2022.
  • Historically, Free Cash Flow has averaged -$34.2 million across 5 years, with a median of -$31.9 million in 2025.
  • Annual changes were most pronounced in 2022 — Free Cash Flow plunged 60.27% — and 2023, when it jumped 44.4%.
  • Rhythm Pharmaceuticals' Free Cash Flow stood at -$29.4 million in 2022, then grew by 0.18% to -$29.4 million in 2023, then advanced by 25.13% to -$22.0 million in 2024, then dropped by 18.49% to -$26.1 million in 2025, then slumped by 67.82% to -$43.8 million in 2026.
  • Business Quant data shows RYTM's Free Cash Flow at -$43.8 million in Q1 2026, -$26.1 million in Q4 2025, and -$31.9 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Free Cash Flow (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 1.01 Bn
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 572.80 Mn
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn -
4 Revolution Medicines 43.64 Bn 43.64 Bn - -389.61 Mn
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 437.80 Mn
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn -2.33 Mn
7 Royalty Pharma 33.72 Bn 35.84 Bn - 477.44 Mn
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 292.04 Mn
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn -95.09 Mn
10 Rhythm Pharmaceuticals 7.95 Bn 7.62 Bn 62.32 Mn -9.15 Mn

Historic Data

Download Data
DateValue
Jun 30, 2026 -9.15 Mn
Jun 30, 2026 -9.15 Mn
Mar 31, 2026 -43.75 Mn
Mar 31, 2026 -43.75 Mn
Dec 31, 2025 -26.07 Mn
Dec 31, 2025 -26.07 Mn
Sep 30, 2025 -31.86 Mn
Sep 30, 2025 -31.86 Mn
Jun 30, 2025 -17.89 Mn
Jun 30, 2025 -17.89 Mn
Mar 31, 2025 -40.25 Mn
Mar 31, 2025 -40.25 Mn
Dec 31, 2024 -22.00 Mn
Dec 31, 2024 -22.00 Mn
Sep 30, 2024 -24.31 Mn
Sep 30, 2024 -24.31 Mn
Jun 30, 2024 -28.02 Mn
Jun 30, 2024 -28.02 Mn
Mar 31, 2024 -39.55 Mn
Mar 31, 2024 -39.55 Mn