Rhythm Pharmaceuticals (RYTM) FCF Margin (2021 - 2026)

Rhythm Pharmaceuticals (RYTM) posted quarterly FCF Margin of 72.78% for Q1 2026, up 5029.0% year-over-year from 1.42% in Q1 2025, and down 59.84% quarter-over-quarter from 45.53% in Q4 2025.

Rhythm Pharmaceuticals (RYTM) FCF Margin (2021 - 2026) Analysis & Trends

Rhythm Pharmaceuticals (RYTM) has reported FCF Margin for 6 consecutive years, with 72.78% the latest figure, recorded in Q1 2026.

  • In Q1 2026, FCF Margin rose 5029.0% year-over-year to 72.78%; the TTM figure through Mar 2026 stood at 55.06% (up 2866.0% YoY), while the FY2025 annual figure was 61.17%, up 2635.0% from the prior year.
  • FCF Margin declined to 72.78% in Q1 2026 per RYTM's latest filing, from 45.53% in the prior quarter.
  • Across five years, FCF Margin topped out at 365.81% in Q4 2022 and bottomed at 3588.72% in Q1 2022.
  • Historically, FCF Margin has averaged 373.33% across 5 years, with a median of 121.26% in 2023.
  • Annual changes were most pronounced in 2022 — FCF Margin jumped 9224842 bps — and 2023, when it sank 48707 bps.
  • Rhythm Pharmaceuticals' FCF Margin stood at 365.81% in 2022, then plunged by 133 bps to 121.26% in 2023, then surged by 57 bps to 52.6% in 2024, then grew by 13 bps to 45.53% in 2025, then sank by 60 bps to 72.78% in 2026.
  • Business Quant data shows RYTM's FCF Margin at 72.78% in Q1 2026, 45.53% in Q4 2025, and 62.12% in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) FCF Margin (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 30.39%
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 13.35%
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn -
4 Revolution Medicines 43.64 Bn 43.64 Bn - -
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 25.68%
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn -77,594.17%
7 Royalty Pharma 33.72 Bn 35.84 Bn - 70.82%
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 22.62%
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn -22.35%
10 Rhythm Pharmaceuticals 7.95 Bn 7.62 Bn 62.32 Mn -12.84%

Historic Data

Download Data
DateValue
Jun 30, 2026 -12.84%
Mar 31, 2026 -72.78%
Dec 31, 2025 -45.53%
Sep 30, 2025 -62.12%
Jun 30, 2025 -36.88%
Mar 31, 2025 -123.07%
Dec 31, 2024 -52.60%
Sep 30, 2024 -73.10%
Jun 30, 2024 -96.37%
Mar 31, 2024 -152.30%
Dec 31, 2023 -121.26%
Sep 30, 2023 -127.60%
Jun 30, 2023 -207.42%
Mar 31, 2023 -318.53%
Dec 31, 2022 365.81%
Sep 30, 2022 -1,205.44%
Jun 30, 2022 -428.73%
Mar 31, 2022 -3,588.72%
Dec 31, 2021 -2,297.96%
Sep 30, 2021 -4,905.93%