Rhythm Pharmaceuticals (RYTM) Enterprise Value (2016 - 2026)
Rhythm Pharmaceuticals (RYTM) posted quarterly Enterprise Value of -$340.6 million for Q1 2026, down 8.31% year-over-year from -$371.5 million in Q1 2025, and up 12.42% quarter-over-quarter from -$388.9 million in Q4 2025.
Rhythm Pharmaceuticals (RYTM) Enterprise Value (2016 - 2026) Analysis & Trends
Rhythm Pharmaceuticals (RYTM) has reported Enterprise Value for 11 consecutive years, with -$340.6 million the latest figure, recorded in Q1 2026.
- In Q1 2026, Enterprise Value fell 8.31% year-over-year to -$340.6 million; the TTM figure through Mar 2026 stood at -$340.6 million (down 8.31% YoY), while the FY2025 annual figure was -$388.9 million, down 21.33% from the prior year.
- Enterprise Value climbed to -$340.6 million in Q1 2026 per RYTM's latest filing, from -$388.9 million in the prior quarter.
- Across five years, Enterprise Value topped out at -$201.7 million in Q1 2024 and bottomed at -$780.1 million in Q3 2025.
- Historically, Enterprise Value has averaged -$325.9 million across 5 years, with a median of -$299.6 million in 2023.
- Annual changes were most pronounced in 2022 — Enterprise Value jumped 40.43% — and 2025, when it slumped 161.02%.
- Rhythm Pharmaceuticals' Enterprise Value stood at -$333.6 million in 2022, then grew by 17.22% to -$276.2 million in 2023, then retreated by 16.07% to -$320.6 million in 2024, then slipped by 21.33% to -$388.9 million in 2025, then advanced by 12.42% to -$340.6 million in 2026.
- Business Quant data shows RYTM's Enterprise Value at -$340.6 million in Q1 2026, -$388.9 million in Q4 2025, and -$780.1 million in Q3 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Enterprise Value (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 128.13 Bn | 120.28 Bn | 2.84 Bn | -7.85 Bn |
| 2 | Regeneron Pharmaceuticals | 112.33 Bn | 104.33 Bn | 3.93 Bn | -7.99 Bn |
| 3 | Argenx Se | 53.24 Bn | 48.05 Bn | 1.41 Bn | -5.18 Bn |
| 4 | Revolution Medicines | 43.64 Bn | 43.64 Bn | - | -3.94 Bn |
| 5 | BeOne Medicines | 39.27 Bn | 34.17 Bn | 1.53 Bn | -5.10 Bn |
| 6 | MindWalk Holdings | 35.32 Bn | 35.31 Bn | 1.82 Bn | -8.46 Mn |
| 7 | Royalty Pharma | 33.72 Bn | 35.84 Bn | - | 2.12 Bn |
| 8 | Alnylam Pharmaceuticals | 30.58 Bn | 27.27 Bn | 992.69 Mn | -3.31 Bn |
| 9 | Insmed | 27.01 Bn | 25.85 Bn | 358.27 Mn | -1.16 Bn |
| 10 | Rhythm Pharmaceuticals | 7.95 Bn | 7.62 Bn | 62.32 Mn | -330.90 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Jun 30, 2026 | -330.90 Mn |
| Mar 31, 2026 | -340.63 Mn |
| Dec 31, 2025 | -388.95 Mn |
| Sep 30, 2025 | -780.07 Mn |
| Jun 30, 2025 | -291.56 Mn |
| Mar 31, 2025 | -314.49 Mn |
| Dec 31, 2024 | -320.57 Mn |
| Sep 30, 2024 | -298.85 Mn |
| Jun 30, 2024 | -319.59 Mn |
| Mar 31, 2024 | -201.66 Mn |
| Dec 31, 2023 | -276.17 Mn |
| Sep 30, 2023 | -299.59 Mn |
| Jun 30, 2023 | -253.93 Mn |
| Mar 31, 2023 | -294.91 Mn |
| Dec 31, 2022 | -333.62 Mn |
| Sep 30, 2022 | -348.12 Mn |
| Jun 30, 2022 | -235.92 Mn |
| Mar 31, 2022 | -241.29 Mn |
| Dec 31, 2021 | -295.18 Mn |
| Sep 30, 2021 | -328.68 Mn |