Rhythm Pharmaceuticals (RYTM) Enterprise Value (2016 - 2026)
Rhythm Pharmaceuticals (RYTM) reported Enterprise Value of -$340.6 million for Q1 2026, down 8.31% year-over-year from -$371.5 million in Q1 2025, and up 12.42% quarter-over-quarter from -$388.9 million in Q4 2025.
Rhythm Pharmaceuticals (RYTM) Enterprise Value (2016 - 2026) Analysis & Trends
Rhythm Pharmaceuticals (RYTM) has 11 years of Enterprise Value data on file, last reported at -$340.6 million in Q1 2026.
- Enterprise Value for Q1 2026 came in at -$340.6 million, down 8.31% year-over-year; the trailing twelve-month figure through Mar 2026 was -$340.6 million (down 8.31% YoY), and the FY2025 annual result was -$388.9 million, down 21.33% from the prior year.
- Enterprise Value rose to -$340.6 million in Q1 2026 per RYTM's latest filing, from -$388.9 million in the prior quarter.
- Over five years, Enterprise Value peaked at -$201.7 million in Q1 2024 and troughed at -$416.7 million in Q3 2025.
- A 5-year average of -$304.5 million and a median of -$299.6 million in 2023 frame the typical range for Enterprise Value.
- The sharpest annual moves came in 2022 and 2025: Enterprise Value jumped 40.43% in 2022, then plunged 55.95% in 2025.
- A 5-year view of Enterprise Value shows it stood at -$333.6 million in 2022, then climbed by 17.22% to -$276.2 million in 2023, then fell by 16.07% to -$320.6 million in 2024, then decreased by 21.33% to -$388.9 million in 2025, then gained by 12.42% to -$340.6 million in 2026.
- Business Quant data shows RYTM's Enterprise Value at -$340.6 million in Q1 2026, -$388.9 million in Q4 2025, and -$416.7 million in Q3 2025.
Powered by 
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Enterprise Value (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | -32.30 Mn |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | -4.14 Mn |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | -286.70 Mn |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | -18.44 Mn |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | -2.77 Mn |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | -7.20 Mn |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | -7.25 Bn |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | -584.73 Mn |
| 10 | Rhythm Pharmaceuticals | 6.59 Bn | 6.25 Bn | 52.96 Mn | -340.63 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -340.63 Mn |
| Dec 31, 2025 | -388.95 Mn |
| Sep 30, 2025 | -416.72 Mn |
| Jun 30, 2025 | -291.03 Mn |
| Mar 31, 2025 | -314.49 Mn |
| Dec 31, 2024 | -320.57 Mn |
| Sep 30, 2024 | -298.85 Mn |
| Jun 30, 2024 | -319.59 Mn |
| Mar 31, 2024 | -201.66 Mn |
| Dec 31, 2023 | -276.17 Mn |
| Sep 30, 2023 | -299.59 Mn |
| Jun 30, 2023 | -253.93 Mn |
| Mar 31, 2023 | -294.91 Mn |
| Dec 31, 2022 | -333.62 Mn |
| Sep 30, 2022 | -348.12 Mn |
| Jun 30, 2022 | -235.92 Mn |
| Mar 31, 2022 | -241.29 Mn |
| Dec 31, 2021 | -295.18 Mn |
| Sep 30, 2021 | -328.68 Mn |
| Jun 30, 2021 | -368.48 Mn |