Rhythm Pharmaceuticals (RYTM) Enterprise Value (2016 - 2026)

Rhythm Pharmaceuticals' (RYTM) quarterly Enterprise Value came in at -$340.6 million in Q1 2026, down 8.31% year-on-year from -$371.5 million in Q1 2025, and up 12.42% on a QoQ basis from -$388.9 million in Q4 2025.

Rhythm Pharmaceuticals (RYTM) Enterprise Value (2016 - 2026) Analysis & Trends

Rhythm Pharmaceuticals (RYTM) has 11 years of Enterprise Value data on file, last reported at -$340.6 million in Q1 2026.

  • On a quarterly basis, Enterprise Value fell 8.31% year-over-year to -$340.6 million in Q1 2026; TTM through Mar 2026 was -$340.6 million, a 8.31% decrease from a year earlier, with the FY2025 full-year figure at -$388.9 million, down 21.33% from the prior year.
  • Enterprise Value for Q1 2026 stood at -$340.6 million, up from -$388.9 million in the prior quarter.
  • Over the last five years, Enterprise Value for RYTM reached as high as -$201.7 million in Q1 2024 and fell as low as -$780.1 million in Q3 2025.
  • Historically, Enterprise Value has averaged -$325.9 million across 5 years, with a median of -$299.6 million in 2023.
  • Across the five-year window, Enterprise Value surged 40.43% in 2022 and plunged 161.02% in 2025, its largest moves.
  • Year by year, Enterprise Value stood at -$333.6 million in 2022, then rose by 17.22% to -$276.2 million in 2023, then slipped by 16.07% to -$320.6 million in 2024, then declined by 21.33% to -$388.9 million in 2025, then grew by 12.42% to -$340.6 million in 2026.
  • Per Business Quant data, the three most recent Enterprise Value figures were -$340.6 million in Q1 2026, -$388.9 million in Q4 2025, and -$780.1 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Enterprise Value (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -283.54 Mn
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -61.40 Mn
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn -4.79 Bn
4 NuCana 279.75 Bn 279.75 Bn - -32.26 Mn
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn -7.25 Bn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn -8.75 Bn
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn -5.18 Bn
9 Revolution Medicines 37.78 Bn 37.78 Bn - -1.91 Bn
10 Rhythm Pharmaceuticals 6.98 Bn 6.64 Bn 52.96 Mn -340.63 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -340.63 Mn
Dec 31, 2025 -388.95 Mn
Sep 30, 2025 -780.07 Mn
Jun 30, 2025 -291.56 Mn
Mar 31, 2025 -314.49 Mn
Dec 31, 2024 -320.57 Mn
Sep 30, 2024 -298.85 Mn
Jun 30, 2024 -319.59 Mn
Mar 31, 2024 -201.66 Mn
Dec 31, 2023 -276.17 Mn
Sep 30, 2023 -299.59 Mn
Jun 30, 2023 -253.93 Mn
Mar 31, 2023 -294.91 Mn
Dec 31, 2022 -333.62 Mn
Sep 30, 2022 -348.12 Mn
Jun 30, 2022 -235.92 Mn
Mar 31, 2022 -241.29 Mn
Dec 31, 2021 -295.18 Mn
Sep 30, 2021 -328.68 Mn
Jun 30, 2021 -368.48 Mn