Rhythm Pharmaceuticals (RYTM) EBITDA (2016 - 2026)
Rhythm Pharmaceuticals' (RYTM) quarterly EBITDA came in at -$52.4 million in Q1 2026, down 11.4% year-on-year from -$59.1 million in Q1 2025, and down 11.26% on a QoQ basis from -$47.1 million in Q4 2025.
Rhythm Pharmaceuticals (RYTM) EBITDA (2016 - 2026) Analysis & Trends
Rhythm Pharmaceuticals (RYTM) has 11 years of EBITDA data on file, last reported at -$52.4 million in Q1 2026.
- On a quarterly basis, EBITDA fell 11.4% year-over-year to -$52.4 million in Q1 2026; TTM through Mar 2026 was -$197.4 million, a 14.34% decrease from a year earlier, with the FY2025 full-year figure at -$192.0 million, up 27.68% from the prior year.
- EBITDA for Q1 2026 stood at -$52.4 million, down from -$47.1 million in the prior quarter.
- Over the last five years, EBITDA for RYTM reached as high as -$39.3 million in Q3 2022 and fell as low as -$139.9 million in Q1 2024.
- Historically, EBITDA has averaged -$51.4 million across 5 years, with a median of -$45.3 million in 2025.
- Across the five-year window, EBITDA sank 166.29% in 2024 and soared 66.4% in 2025, its largest moves.
- Year by year, EBITDA stood at -$42.1 million in 2022, then gained by 1.99% to -$41.3 million in 2023, then advanced by 0.02% to -$41.3 million in 2024, then fell by 14.08% to -$47.1 million in 2025, then fell by 11.26% to -$52.4 million in 2026.
- Per Business Quant data, the three most recent EBITDA figures were -$52.4 million in Q1 2026, -$47.1 million in Q4 2025, and -$52.7 million in Q3 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 67,072.09 Bn | 67,072.09 Bn | - | -27.75 Mn |
| 2 | Nanobiotix | 1,894.61 Bn | 1,894.55 Bn | - | - |
| 3 | Akari Therapeutics | 1,014.18 Bn | 1,014.18 Bn | - | -15.76 Mn |
| 4 | BeOne Medicines | 471.64 Bn | 466.85 Bn | 1.35 Bn | 249.90 Mn |
| 5 | Vertex Pharmaceuticals | 121.72 Bn | 114.47 Bn | 2.59 Bn | 1.14 Bn |
| 6 | Regeneron Pharmaceuticals | 68.28 Bn | 59.52 Bn | 3.31 Bn | 642.90 Mn |
| 7 | Belite Bio | 61.40 Bn | 61.40 Bn | - | -32.68 Mn |
| 8 | Argenx Se | 56.94 Bn | 56.94 Bn | 1.18 Bn | 394.00 Mn |
| 9 | Revolution Medicines | 37.37 Bn | 37.37 Bn | - | -445.22 Mn |
| 10 | Rhythm Pharmaceuticals | 6.99 Bn | 6.64 Bn | 52.96 Mn | -52.36 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -52.36 Mn |
| Dec 31, 2025 | -47.06 Mn |
| Sep 30, 2025 | -52.65 Mn |
| Jun 30, 2025 | -45.30 Mn |
| Mar 31, 2025 | -47.00 Mn |
| Dec 31, 2024 | -41.26 Mn |
| Sep 30, 2024 | -43.89 Mn |
| Jun 30, 2024 | -40.48 Mn |
| Mar 31, 2024 | -139.89 Mn |
| Dec 31, 2023 | -41.27 Mn |
| Sep 30, 2023 | -43.95 Mn |
| Jun 30, 2023 | -46.60 Mn |
| Mar 31, 2023 | -52.53 Mn |
| Dec 31, 2022 | -42.10 Mn |
| Sep 30, 2022 | -39.27 Mn |
| Jun 30, 2022 | -45.10 Mn |
| Mar 31, 2022 | -52.69 Mn |
| Dec 31, 2021 | -50.99 Mn |
| Sep 30, 2021 | -44.24 Mn |
| Jun 30, 2021 | -40.43 Mn |