Rhythm Pharmaceuticals (RYTM) EBITDA (2016 - 2026)
Rhythm Pharmaceuticals (RYTM) reported EBITDA of -$54.4 million for Q1 2026, down 7.02% year-over-year from -$58.5 million in Q1 2025, and down 15.59% quarter-over-quarter from -$47.1 million in Q4 2025.
Rhythm Pharmaceuticals (RYTM) EBITDA (2016 - 2026) Analysis & Trends
Rhythm Pharmaceuticals (RYTM) has 11 years of EBITDA data on file, last reported at -$54.4 million in Q1 2026.
- EBITDA for Q1 2026 came in at -$54.4 million, down 7.02% year-over-year; the trailing twelve-month figure through Mar 2026 was -$199.4 million (down 13.01% YoY), and the FY2025 annual result was -$202.7 million, up 23.45% from the prior year.
- EBITDA slipped to -$54.4 million in Q1 2026 per RYTM's latest filing, from -$47.1 million in the prior quarter.
- Over five years, EBITDA peaked at -$39.3 million in Q3 2022 and troughed at -$139.9 million in Q1 2024.
- A 5-year average of -$51.7 million and a median of -$45.3 million in 2025 frame the typical range for EBITDA.
- The sharpest annual moves came in 2024 and 2025: EBITDA tumbled 166.29% in 2024, then surged 63.66% in 2025.
- A 5-year view of EBITDA shows it stood at -$42.1 million in 2022, then grew by 1.99% to -$41.3 million in 2023, then increased by 0.02% to -$41.3 million in 2024, then slipped by 14.08% to -$47.1 million in 2025, then dropped by 15.59% to -$54.4 million in 2026.
- Business Quant data shows RYTM's EBITDA at -$54.4 million in Q1 2026, -$47.1 million in Q4 2025, and -$52.7 million in Q3 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | -26.92 Mn |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | -13.63 Mn |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | -19.70 Mn |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | -3.82 Mn |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | -14.44 Mn |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | -752,618.00 |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 1.14 Bn |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | -65.83 Mn |
| 10 | Rhythm Pharmaceuticals | 6.59 Bn | 6.25 Bn | 52.96 Mn | -54.40 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -54.40 Mn |
| Dec 31, 2025 | -47.06 Mn |
| Sep 30, 2025 | -52.65 Mn |
| Jun 30, 2025 | -45.30 Mn |
| Mar 31, 2025 | -50.83 Mn |
| Dec 31, 2024 | -41.26 Mn |
| Sep 30, 2024 | -43.89 Mn |
| Jun 30, 2024 | -40.48 Mn |
| Mar 31, 2024 | -139.89 Mn |
| Dec 31, 2023 | -41.27 Mn |
| Sep 30, 2023 | -43.95 Mn |
| Jun 30, 2023 | -46.60 Mn |
| Mar 31, 2023 | -52.53 Mn |
| Dec 31, 2022 | -42.10 Mn |
| Sep 30, 2022 | -39.27 Mn |
| Jun 30, 2022 | -45.10 Mn |
| Mar 31, 2022 | -52.69 Mn |
| Dec 31, 2021 | -50.99 Mn |
| Sep 30, 2021 | -44.24 Mn |
| Jun 30, 2021 | -40.43 Mn |