Rhythm Pharmaceuticals (RYTM) EBITDA (2016 - 2026)
Rhythm Pharmaceuticals (RYTM) posted quarterly EBITDA of -$52.4 million for Q1 2026, down 11.4% year-over-year from -$59.1 million in Q1 2025, and down 11.26% quarter-over-quarter from -$47.1 million in Q4 2025.
Rhythm Pharmaceuticals (RYTM) EBITDA (2016 - 2026) Analysis & Trends
Rhythm Pharmaceuticals (RYTM) has reported EBITDA for 11 consecutive years, with -$52.4 million the latest figure, recorded in Q1 2026.
- In Q1 2026, EBITDA fell 11.4% year-over-year to -$52.4 million; the TTM figure through Mar 2026 stood at -$197.4 million (down 14.34% YoY), while the FY2025 annual figure was -$192.0 million, up 27.68% from the prior year.
- EBITDA fell to -$52.4 million in Q1 2026 per RYTM's latest filing, from -$47.1 million in the prior quarter.
- Across five years, EBITDA topped out at -$39.3 million in Q3 2022 and bottomed at -$139.9 million in Q1 2024.
- Historically, EBITDA has averaged -$51.4 million across 5 years, with a median of -$45.3 million in 2025.
- Annual changes were most pronounced in 2024 — EBITDA tumbled 166.29% — and 2025, when it surged 66.4%.
- Rhythm Pharmaceuticals' EBITDA stood at -$42.1 million in 2022, then increased by 1.99% to -$41.3 million in 2023, then rose by 0.02% to -$41.3 million in 2024, then dropped by 14.08% to -$47.1 million in 2025, then dropped by 11.26% to -$52.4 million in 2026.
- Business Quant data shows RYTM's EBITDA at -$52.4 million in Q1 2026, -$47.1 million in Q4 2025, and -$52.7 million in Q3 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 128.13 Bn | 120.28 Bn | 2.84 Bn | 1.25 Bn |
| 2 | Regeneron Pharmaceuticals | 112.33 Bn | 104.33 Bn | 3.93 Bn | 1.29 Bn |
| 3 | Argenx Se | 53.24 Bn | 48.05 Bn | 1.41 Bn | 493.00 Mn |
| 4 | Revolution Medicines | 43.64 Bn | 43.64 Bn | - | -505.13 Mn |
| 5 | BeOne Medicines | 39.27 Bn | 34.17 Bn | 1.53 Bn | 325.05 Mn |
| 6 | MindWalk Holdings | 35.32 Bn | 35.31 Bn | 1.82 Bn | -2.33 Bn |
| 7 | Royalty Pharma | 33.72 Bn | 35.84 Bn | - | 133.12 Mn |
| 8 | Alnylam Pharmaceuticals | 30.58 Bn | 27.27 Bn | 992.69 Mn | 231.44 Mn |
| 9 | Insmed | 27.01 Bn | 25.85 Bn | 358.27 Mn | -1.55 Mn |
| 10 | Rhythm Pharmaceuticals | 7.95 Bn | 7.62 Bn | 62.32 Mn | -48.55 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Jun 30, 2026 | -48.55 Mn |
| Mar 31, 2026 | -52.36 Mn |
| Dec 31, 2025 | -47.06 Mn |
| Sep 30, 2025 | -52.65 Mn |
| Jun 30, 2025 | -45.30 Mn |
| Mar 31, 2025 | -47.00 Mn |
| Dec 31, 2024 | -41.26 Mn |
| Sep 30, 2024 | -43.89 Mn |
| Jun 30, 2024 | -40.48 Mn |
| Mar 31, 2024 | -139.89 Mn |
| Dec 31, 2023 | -41.27 Mn |
| Sep 30, 2023 | -43.95 Mn |
| Jun 30, 2023 | -46.60 Mn |
| Mar 31, 2023 | -52.53 Mn |
| Dec 31, 2022 | -42.10 Mn |
| Sep 30, 2022 | -39.27 Mn |
| Jun 30, 2022 | -45.10 Mn |
| Mar 31, 2022 | -52.69 Mn |
| Dec 31, 2021 | -50.99 Mn |
| Sep 30, 2021 | -44.24 Mn |