Growth Metrics

Rhythm Pharmaceuticals (RYTM) EBIT (2016 - 2026)

Rhythm Pharmaceuticals (RYTM) reported EBIT of -$52.4 million for Q1 2026, down 11.4% year-over-year from -$59.1 million in Q1 2025, and down 11.26% on a QoQ basis from -$47.1 million in Q4 2025.

Rhythm Pharmaceuticals (RYTM) has 11 years of EBIT data on file, last reported at -$52.4 million in Q1 2026.

  • Quarterly EBIT fell 11.4% year-over-year to -$52.4 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$197.4 million (down 14.34% YoY) and the FY2025 annual result came in at -$192.0 million, up 27.68% from the prior year.
  • EBIT eased to -$52.4 million in Q1 2026 per RYTM's latest filing, from -$47.1 million in the prior quarter.
  • Across five years, EBIT topped out at -$39.3 million in Q3 2022 and bottomed at -$139.9 million in Q1 2024.
  • The 5-year median for EBIT is -$45.3 million (2025), against an average of -$51.4 million.
  • The widest annual swing landed in 2024, when EBIT sank 166.29%; it then soared 66.4% in 2025.
  • Tracing RYTM's EBIT over 5 years: stood at -$42.1 million in 2022, then advanced by 1.99% to -$41.3 million in 2023, then climbed by 0.02% to -$41.3 million in 2024, then retreated by 14.08% to -$47.1 million in 2025, then retreated by 11.26% to -$52.4 million in 2026.
  • Per Business Quant, the three latest RYTM EBIT figures stand at -$52.4 million (Q1 2026), -$47.1 million (Q4 2025), and -$52.7 million (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBIT (Qtr)
1 Quantum Biopharma 1,216,509.61 Bn 1,216,509.61 Bn - -2.97 Mn
2 Alterity Therapeutics 764,224.41 Bn 764,224.38 Bn - -
3 Legend Biotech 2,716.00 Bn 2,715.71 Bn 242.10 Mn -19.70 Mn
4 Nanobiotix 2,248.83 Bn 2,248.77 Bn - -
5 Akari Therapeutics 1,951.18 Bn 1,951.17 Bn - -15.76 Mn
6 Vertex Pharmaceuticals 113.69 Bn 106.44 Bn 2.59 Bn 1.14 Bn
7 Evaxion A 64.16 Bn 64.14 Bn - -3.82 Mn
8 Regeneron Pharmaceuticals 63.94 Bn 55.18 Bn 3.31 Bn 642.90 Mn
9 Alnylam Pharmaceuticals 40.13 Bn 37.12 Bn 959.66 Mn 268.64 Mn
10 Rhythm Pharmaceuticals 6.00 Bn 5.66 Bn 52.96 Mn -52.36 Mn

Historic Data

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DateValue
Mar 31, 2026 -52.36 Mn
Dec 31, 2025 -47.06 Mn
Sep 30, 2025 -52.65 Mn
Jun 30, 2025 -45.30 Mn
Mar 31, 2025 -47.00 Mn
Dec 31, 2024 -41.26 Mn
Sep 30, 2024 -43.89 Mn
Jun 30, 2024 -40.48 Mn
Mar 31, 2024 -139.89 Mn
Dec 31, 2023 -41.27 Mn
Sep 30, 2023 -43.95 Mn
Jun 30, 2023 -46.60 Mn
Mar 31, 2023 -52.53 Mn
Dec 31, 2022 -42.10 Mn
Sep 30, 2022 -39.27 Mn
Jun 30, 2022 -45.10 Mn
Mar 31, 2022 -52.69 Mn
Dec 31, 2021 -50.99 Mn
Sep 30, 2021 -44.24 Mn
Jun 30, 2021 -40.43 Mn
Mar 31, 2021 -34.40 Mn
Dec 31, 2020 -35.07 Mn
Sep 30, 2020 -34.28 Mn
Jun 30, 2020 -31.92 Mn
Mar 31, 2020 -35.30 Mn
Dec 31, 2019 -34.22 Mn
Sep 30, 2019 -37.11 Mn
Jun 30, 2019 -44.15 Mn
Mar 31, 2019 -30.52 Mn
Dec 31, 2018 -27.15 Mn
Sep 30, 2018 -19.24 Mn
Jun 30, 2018 -15.02 Mn
Mar 31, 2018 -17.00 Mn
Dec 31, 2017 -10.98 Mn
Sep 30, 2017 -8.29 Mn
Jun 30, 2017 -6.75 Mn
Mar 31, 2017 -6.39 Mn
Dec 31, 2016 -8.38 Mn
Sep 30, 2016 -6.40 Mn