Rhythm Pharmaceuticals (RYTM) Change in Cash (2016 - 2026)

Rhythm Pharmaceuticals (RYTM) reported Change in Cash of $7.9 million for Q1 2026, down 53.33% year-over-year from $17.0 million in Q1 2025, and up 281.63% quarter-over-quarter from $2.1 million in Q4 2025.

Rhythm Pharmaceuticals (RYTM) Change in Cash (2016 - 2026) Analysis & Trends

Rhythm Pharmaceuticals (RYTM) has 11 years of Change in Cash data on file, last reported at $7.9 million in Q1 2026.

  • Change in Cash for Q1 2026 came in at $7.9 million, down 53.33% year-over-year; the trailing twelve-month figure through Mar 2026 was -$43.8 million (down 183.2% YoY), and the FY2025 annual result was -$34.8 million, down 219.14% from the prior year.
  • Change in Cash advanced to $7.9 million in Q1 2026 per RYTM's latest filing, from $2.1 million in the prior quarter.
  • Over five years, Change in Cash peaked at $108.2 million in Q2 2024 and troughed at -$114.1 million in Q3 2024.
  • A 5-year average of $186000.0 and a median of $6.0 million in 2023 frame the typical range for Change in Cash.
  • The sharpest annual moves came in 2023 and 2024: Change in Cash plunged 193.4% in 2023, then jumped 1697.11% in 2024.
  • A 5-year view of Change in Cash shows it stood at -$57.4 million in 2022, then surged by 92.14% to -$4.5 million in 2023, then soared by 1022.38% to $41.6 million in 2024, then sank by 95.02% to $2.1 million in 2025, then soared by 281.63% to $7.9 million in 2026.
  • Business Quant data shows RYTM's Change in Cash at $7.9 million in Q1 2026, $2.1 million in Q4 2025, and -$83.4 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Change in Cash (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - 2.44 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn 623.00 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -2.44 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 417.10 Mn
9 Abivax 91.96 Bn 91.96 Bn - -45.97 Mn
10 Rhythm Pharmaceuticals 6.59 Bn 6.25 Bn 52.96 Mn 7.92 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 7.92 Mn
Dec 31, 2025 2.07 Mn
Sep 30, 2025 -83.36 Mn
Jun 30, 2025 29.55 Mn
Mar 31, 2025 16.96 Mn
Dec 31, 2024 41.62 Mn
Sep 30, 2024 -114.15 Mn
Jun 30, 2024 108.24 Mn
Mar 31, 2024 -6.52 Mn
Dec 31, 2023 -4.51 Mn
Sep 30, 2023 -51.09 Mn
Jun 30, 2023 6.02 Mn
Mar 31, 2023 -18.02 Mn
Dec 31, 2022 -57.41 Mn
Sep 30, 2022 71.88 Mn
Jun 30, 2022 34.67 Mn
Mar 31, 2022 19.29 Mn
Dec 31, 2021 -33.12 Mn
Sep 30, 2021 23.03 Mn
Jun 30, 2021 -17.93 Mn