Rhythm Pharmaceuticals (RYTM) Change in Cash (2016 - 2026)

Rhythm Pharmaceuticals (RYTM) posted quarterly Change in Cash of $7.9 million for Q1 2026, down 53.33% year-over-year from $17.0 million in Q1 2025, and up 281.63% quarter-over-quarter from $2.1 million in Q4 2025.

Rhythm Pharmaceuticals (RYTM) Change in Cash (2016 - 2026) Analysis & Trends

Rhythm Pharmaceuticals (RYTM) has reported Change in Cash for 11 consecutive years, with $7.9 million the latest figure, recorded in Q1 2026.

  • In Q1 2026, Change in Cash fell 53.33% year-over-year to $7.9 million; the TTM figure through Mar 2026 stood at -$43.8 million (down 183.2% YoY), while the FY2025 annual figure was -$34.8 million, down 219.14% from the prior year.
  • Change in Cash rose to $7.9 million in Q1 2026 per RYTM's latest filing, from $2.1 million in the prior quarter.
  • Across five years, Change in Cash topped out at $108.2 million in Q2 2024 and bottomed at -$114.1 million in Q3 2024.
  • Historically, Change in Cash has averaged $186000.0 across 5 years, with a median of $6.0 million in 2023.
  • Annual changes were most pronounced in 2023 — Change in Cash plunged 193.4% — and 2024, when it jumped 1697.11%.
  • Rhythm Pharmaceuticals' Change in Cash stood at -$57.4 million in 2022, then soared by 92.14% to -$4.5 million in 2023, then jumped by 1022.38% to $41.6 million in 2024, then slumped by 95.02% to $2.1 million in 2025, then jumped by 281.63% to $7.9 million in 2026.
  • Business Quant data shows RYTM's Change in Cash at $7.9 million in Q1 2026, $2.1 million in Q4 2025, and -$83.4 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Change in Cash (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 649.20 Mn
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn -504.60 Mn
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn -
4 Revolution Medicines 43.64 Bn 43.64 Bn - 374.50 Mn
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 427.25 Mn
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn -1.97 Mn
7 Royalty Pharma 33.72 Bn 35.84 Bn - 225.59 Mn
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn -2.94 Mn
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn -37.42 Mn
10 Rhythm Pharmaceuticals 7.95 Bn 7.62 Bn 62.32 Mn 3.48 Mn

Historic Data

Download Data
DateValue
Jun 30, 2026 3.48 Mn
Mar 31, 2026 7.92 Mn
Dec 31, 2025 2.07 Mn
Sep 30, 2025 -83.36 Mn
Jun 30, 2025 29.55 Mn
Mar 31, 2025 16.96 Mn
Dec 31, 2024 41.62 Mn
Sep 30, 2024 -114.15 Mn
Jun 30, 2024 108.24 Mn
Mar 31, 2024 -6.52 Mn
Dec 31, 2023 -4.51 Mn
Sep 30, 2023 -51.09 Mn
Jun 30, 2023 6.02 Mn
Mar 31, 2023 -18.02 Mn
Dec 31, 2022 -57.41 Mn
Sep 30, 2022 71.88 Mn
Jun 30, 2022 34.67 Mn
Mar 31, 2022 19.29 Mn
Dec 31, 2021 -33.12 Mn
Sep 30, 2021 23.03 Mn