Royalty Pharma (RPRX) Long-Term Debt Issuances (2020 - 2025)

Royalty Pharma (RPRX) posted Long-Term Debt Issuances of -$275.0 million for Q4 2025, down 121.57% sequentially from $1.3 billion in Q3 2025.

Royalty Pharma (RPRX) Long-Term Debt Issuances (2020 - 2025) Analysis & Trends

Royalty Pharma has reported Long-Term Debt Issuances for 5 years, with the latest figure at -$275.0 million in Q4 2025.

Quarterly Long-Term Debt Issuances changed N/A year-over-year to -$275.0 million in Q4 2025, while the trailing twelve-month figure through Dec 2025 was -$471.2 million (changed 0.0% YoY) and the FY2025 annual result came in at $1.0 billion, changed N/A from the prior year.
Long-Term Debt Issuances declined to -$275.0 million in Q4 2025 per RPRX's latest filing, from $1.3 billion in the prior quarter.
Over five years, Long-Term Debt Issuances peaked at $1.3 billion in Q3 2025 and troughed at -$1.5 billion in Q3 2024.
A 4-year average of $88.1 million and a median of $362.5 million in 2023 frame the typical range for Long-Term Debt Issuances.
The sharpest annual moves came in 2021 and 2025: Long-Term Debt Issuances sank 78.25% in 2021, then jumped 186.66% in 2025.
Over 4 years, Long-Term Debt Issuances stood at -$1.3 billion in 2021, then soared by 178.58% to $1.0 billion in 2023, then sank by 247.12% to -$1.5 billion in 2024, then jumped by 81.31% to -$275.0 million in 2025.
According to Business Quant data, Long-Term Debt Issuances over the past three periods registered -$275.0 million, $1.3 billion, and -$1.5 billion for Q4 2025, Q3 2025, and Q3 2024 respectively.

#	Company	Market Cap	Enterprise Value	Gross Profit (Qtr)	Long-Term Debt Issuances (Qtr)
1	Vertex Pharmaceuticals	128.13 Bn	120.28 Bn	2.84 Bn	-
2	Regeneron Pharmaceuticals	112.33 Bn	104.33 Bn	3.93 Bn	-
3	Argenx Se	53.24 Bn	48.05 Bn	1.41 Bn	-
4	Revolution Medicines	43.64 Bn	43.64 Bn	-	-
5	BeOne Medicines	39.27 Bn	34.17 Bn	1.53 Bn	-
6	MindWalk Holdings	35.32 Bn	35.31 Bn	1.82 Bn	-675,522.58
7	Royalty Pharma	33.72 Bn	35.84 Bn	-	-
8	Alnylam Pharmaceuticals	30.58 Bn	27.27 Bn	992.69 Mn	-
9	Insmed	27.01 Bn	25.85 Bn	358.27 Mn	-
10	Roivant Sciences	26.16 Bn	26.85 Bn	1.16 Mn	-

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