Pyxis Oncology (PYXS) Net Income towards Common Stockholders (2020 - 2025)

Pyxis Oncology's (PYXS) quarterly Net Income towards Common Stockholders came in at -$18.4 million in Q4 2025, up 48.3% year-on-year from -$12.4 million in Q4 2024, and up 16.43% on a QoQ basis from -$22.0 million in Q3 2025.

Pyxis Oncology (PYXS) Net Income towards Common Stockholders (2020 - 2025) Analysis & Trends

Pyxis Oncology (PYXS) has 6 years of Net Income towards Common Stockholders data on file, last reported at -$18.4 million in Q4 2025.

  • On a quarterly basis, Net Income towards Common Stockholders rose 48.3% year-over-year to -$18.4 million in Q4 2025; TTM through Dec 2025 was -$81.3 million, a 5.25% increase from a year earlier, with the FY2025 full-year figure at -$79.6 million, down 2.96% from the prior year.
  • Net Income towards Common Stockholders for Q4 2025 stood at -$18.4 million, up from -$22.0 million in the prior quarter.
  • Over the last five years, Net Income towards Common Stockholders for PYXS reached as high as -$5.9 million in Q2 2021 and fell as low as -$46.4 million in Q3 2021.
  • Historically, Net Income towards Common Stockholders has averaged -$26.0 million across 5 years, with a median of -$23.3 million in 2023.
  • Across the five-year window, Net Income towards Common Stockholders plunged 1353.15% in 2021 and jumped 54.22% in 2024, its largest moves.
  • Year by year, Net Income towards Common Stockholders stood at -$32.8 million in 2021, then retreated by 8.01% to -$35.5 million in 2022, then jumped by 50.45% to -$17.6 million in 2023, then slumped by 102.42% to -$35.6 million in 2024, then jumped by 48.3% to -$18.4 million in 2025.
  • Per Business Quant data, the three most recent Net Income towards Common Stockholders figures were -$18.4 million in Q4 2025, -$22.0 million in Q3 2025, and -$18.4 million in Q2 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Net Income (Qtr)
1 Oculis Holding AG 66,801.52 Bn 66,801.23 Bn - -625.73
2 Nanobiotix 1,908.00 Bn 1,907.94 Bn - -
3 Akari Therapeutics 959.56 Bn 959.56 Bn - -14.46 Mn
4 BeOne Medicines 472.27 Bn 467.47 Bn 1.35 Bn 227.36 Mn
5 Vertex Pharmaceuticals 122.18 Bn 114.93 Bn 2.59 Bn 1.03 Bn
6 Regeneron Pharmaceuticals 70.08 Bn 61.32 Bn 3.31 Bn 727.20 Mn
7 Belite Bio 62.34 Bn 62.34 Bn - -0.68
8 Argenx Se 55.86 Bn 50.68 Bn 1.41 Bn 472.00 Mn
9 Alnylam Pharmaceuticals 37.50 Bn 34.49 Bn 959.66 Mn 205.99 Mn
10 Pyxis Oncology 181.46 Mn 114.60 Mn 8.65 Mn -18.39 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 -18.39 Mn
Sep 30, 2025 -22.00 Mn
Jun 30, 2025 -18.35 Mn
Mar 31, 2025 -22.56 Mn
Dec 31, 2024 -35.57 Mn
Sep 30, 2024 -21.20 Mn
Jun 30, 2024 -17.30 Mn
Mar 31, 2024 -11.73 Mn
Dec 31, 2023 -17.57 Mn
Sep 30, 2023 -23.99 Mn
Jun 30, 2023 -17.90 Mn
Mar 31, 2023 -25.63 Mn
Dec 31, 2022 -35.46 Mn
Sep 30, 2022 -40.79 Mn
Jun 30, 2022 -39.05 Mn
Mar 31, 2022 -31.82 Mn
Dec 31, 2021 -32.83 Mn
Sep 30, 2021 -46.37 Mn
Jun 30, 2021 -5.94 Mn
Mar 31, 2021 -35.73 Mn