Pyxis Oncology (PYXS) Invested Capital (2020 - 2025)

Pyxis Oncology (PYXS) reported Invested Capital of $53.4 million for Q4 2025, down 55.77% year-over-year from $120.8 million in Q4 2024, and down 22.35% quarter-over-quarter from $68.8 million in Q3 2025.

Pyxis Oncology (PYXS) Invested Capital (2020 - 2025) Analysis & Trends

Pyxis Oncology (PYXS) has 6 years of Invested Capital data on file, last reported at $53.4 million in Q4 2025.

  • Invested Capital for Q4 2025 came in at $53.4 million, down 55.77% year-over-year; the trailing twelve-month figure through Dec 2025 was $53.4 million (down 55.77% YoY), and the FY2025 annual result was $53.4 million, down 55.77% from the prior year.
  • Invested Capital fell to $53.4 million in Q4 2025 per PYXS's latest filing, from $68.8 million in the prior quarter.
  • Over five years, Invested Capital peaked at $261.3 million in Q4 2021 and troughed at -$62.3 million in Q3 2021.
  • A 5-year average of $119.4 million and a median of $141.6 million in 2023 frame the typical range for Invested Capital.
  • On a YoY basis, Invested Capital climbed as much as 1770.27% in 2021 and fell as far as 462.06% in 2021.
  • A 5-year view of Invested Capital shows it stood at $261.3 million in 2021, then sank by 38.46% to $160.8 million in 2022, then retreated by 21.84% to $125.7 million in 2023, then slipped by 3.94% to $120.8 million in 2024, then tumbled by 55.77% to $53.4 million in 2025.
  • Business Quant data shows PYXS's Invested Capital at $53.4 million in Q4 2025, $68.8 million in Q3 2025, and $87.6 million in Q2 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Invested Cap. (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - 7.14 Bn
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - 795.79 Mn
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - 595,226.00
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn 1.00 Bn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - 14.38 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 19.36 Bn
9 Abivax 91.96 Bn 91.96 Bn - 502.95 Mn
10 Pyxis Oncology 125.84 Mn 108.95 Mn 8.65 Mn 53.41 Mn

Historic Data

Download Data
DateValue
Dec 31, 2025 53.41 Mn
Sep 30, 2025 68.78 Mn
Jun 30, 2025 87.64 Mn
Mar 31, 2025 103.10 Mn
Dec 31, 2024 120.75 Mn
Sep 30, 2024 153.68 Mn
Jun 30, 2024 169.79 Mn
Mar 31, 2024 184.16 Mn
Dec 31, 2023 125.70 Mn
Sep 30, 2023 137.95 Mn
Jun 30, 2023 145.28 Mn
Mar 31, 2023 152.16 Mn
Dec 31, 2022 160.82 Mn
Sep 30, 2022 188.75 Mn
Jun 30, 2022 211.97 Mn
Mar 31, 2022 233.51 Mn
Dec 31, 2021 261.31 Mn
Sep 30, 2021 -62.32 Mn
Jun 30, 2021 -57.59 Mn
Mar 31, 2021 -50.02 Mn