Alnylam Pharmaceuticals (ALNY) Invested Capital (2016 - 2025)
Alnylam Pharmaceuticals' (ALNY) quarterly Invested Capital came in at $789.2 million in Q4 2025, up 390.51% on a YoY basis from $160.9 million in Q4 2024, and up 122.18% quarter-over-quarter from $355.2 million in Q3 2025.
Analysis
Alnylam Pharmaceuticals (ALNY) Invested Capital (2016 - 2025) Analysis & Trends
Alnylam Pharmaceuticals (ALNY) has reported Invested Capital for 9 consecutive years, with $789.2 million the latest figure, recorded in Q4 2025.
- For the quarter ending Q4 2025, Invested Capital rose 390.51% year-over-year to $789.2 million; the trailing twelve-month figure through Dec 2025 stood at $789.2 million (up 390.51% YoY), and the FY2025 full-year result was $789.2 million, up 390.51% from the prior year.
- Invested Capital grew to $789.2 million in Q4 2025 per ALNY's latest filing, from $355.2 million in the prior quarter.
- Across five years, Invested Capital topped out at $1.3 billion in Q2 2021 and bottomed at -$158.2 million in Q4 2022.
- Historically, Invested Capital has averaged $763.1 million across 4 years, with a median of $821.5 million in 2022.
- The sharpest annual moves came in 2022 and 2025: Invested Capital sank 112.52% in 2022, then jumped 390.51% in 2025.
- Over 4 years, Invested Capital stood at $1.3 billion in 2021, then tumbled by 112.52% to -$158.2 million in 2022, then surged by 201.68% to $160.9 million in 2024, then surged by 390.51% to $789.2 million in 2025.
- According to Business Quant data, Invested Capital over the past three periods registered $789.2 million, $355.2 million, and $676.1 million for Q4 2025, Q3 2025, and Q2 2025 respectively.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Invested Cap. (Qtr) |
|---|---|---|---|---|---|
| 1 | Amgen | 236.37 Bn | 222.38 Bn | 7.24 Bn | 74.44 Bn |
| 2 | Gilead Sciences | 187.38 Bn | 184.12 Bn | 6.22 Bn | 40.49 Bn |
| 3 | Vertex Pharmaceuticals | 138.36 Bn | 130.51 Bn | 2.84 Bn | - |
| 4 | Regeneron Pharmaceuticals | 85.09 Bn | 77.10 Bn | 3.93 Bn | 33.70 Bn |
| 5 | Argenx Se | 63.93 Bn | 58.75 Bn | 1.37 Bn | - |
| 6 | Moderna | 58.07 Bn | 52.94 Bn | 52.00 Mn | 7.35 Bn |
| 7 | Alnylam Pharmaceuticals | 35.59 Bn | 32.28 Bn | 992.69 Mn | - |
| 8 | Biogen | 32.63 Bn | 31.34 Bn | 1.96 Bn | 26.94 Bn |
| 9 | Insmed | 27.57 Bn | 26.41 Bn | 358.27 Mn | 1.30 Bn |
| 10 | BioNTech SE | 26.24 Bn | 12.58 Bn | 10.00 Mn | 20.87 Bn |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Dec 31, 2025 | 789.18 Mn |
| Sep 30, 2025 | 355.19 Mn |
| Jun 30, 2025 | 676.15 Mn |
| Mar 31, 2025 | 544.24 Mn |
| Dec 31, 2024 | 160.89 Mn |
| Dec 31, 2022 | -158.22 Mn |
| Jun 30, 2022 | 853.76 Mn |
| Mar 31, 2022 | 1.08 Bn |
| Dec 31, 2021 | 1.26 Bn |
| Sep 30, 2021 | 1.19 Bn |
| Jun 30, 2021 | 1.29 Bn |
| Mar 31, 2021 | 1.12 Bn |
| Dec 31, 2020 | 1.21 Bn |
| Dec 31, 2019 | 1.44 Bn |
| Sep 30, 2019 | 1.61 Bn |
| Jun 30, 2019 | 1.79 Bn |
| Mar 31, 2019 | 1.58 Bn |
| Dec 31, 2018 | 1.33 Bn |
| Sep 30, 2018 | 1.51 Bn |
| Jun 30, 2018 | 1.65 Bn |