Pyxis Oncology (PYXS) EPS (Basic) (2020 - 2026)
Pyxis Oncology (PYXS) posted quarterly EPS (Basic) of -$0.3 for Q4 2025, up 51.38% year-over-year from -$0.2 in Q4 2024, and up 15.87% quarter-over-quarter from -$0.35 in Q3 2025.
Pyxis Oncology (PYXS) EPS (Basic) (2020 - 2026) Analysis & Trends
Pyxis Oncology (PYXS) has reported EPS (Basic) for 6 consecutive years, with -$0.3 the latest figure, recorded in Q4 2025.
- In Q4 2025, EPS (Basic) rose 51.38% year-over-year to -$0.3; the TTM figure through Dec 2025 stood at -$1.31 (up 10.89% YoY), while the FY2025 annual figure was -$1.28, up 3.16% from the prior year.
- EPS (Basic) grew to -$0.3 in Q4 2025 per PYXS's latest filing, from -$0.35 in the prior quarter.
- Across five years, EPS (Basic) topped out at -$0.23 in Q1 2024 and bottomed at -$29.32 in Q3 2021.
- Historically, EPS (Basic) has averaged -$3.72 across 5 years, with a median of -$0.59 in 2023.
- Annual changes were most pronounced in 2021 — EPS (Basic) slumped 899.84% — and 2022, when it surged 96.28%.
- Pyxis Oncology's EPS (Basic) stood at -$4.96 in 2021, then jumped by 78.38% to -$1.07 in 2022, then jumped by 53.11% to -$0.5 in 2023, then decreased by 20.9% to -$0.61 in 2024, then jumped by 51.38% to -$0.3 in 2025.
- Business Quant data shows PYXS's EPS (Basic) at -$0.3 in Q4 2025, -$0.35 in Q3 2025, and -$0.3 in Q2 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EPS (Basic) (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 137.11 Bn | 129.26 Bn | 2.84 Bn | 4.34 |
| 2 | Regeneron Pharmaceuticals | 84.98 Bn | 76.99 Bn | 3.93 Bn | 12.62 |
| 3 | Argenx Se | 64.52 Bn | 59.33 Bn | 1.37 Bn | 7.59 |
| 4 | Moderna | 53.23 Bn | 48.09 Bn | 52.00 Mn | -1.96 |
| 5 | BeOne Medicines | 41.23 Bn | 36.14 Bn | 1.53 Bn | 2.12 |
| 6 | Alnylam Pharmaceuticals | 30.65 Bn | 27.34 Bn | 992.69 Mn | 1.23 |
| 7 | Insmed | 27.15 Bn | 25.99 Bn | 358.27 Mn | -0.06 |
| 8 | Royalty Pharma | 26.98 Bn | 26.14 Bn | - | 0.18 |
| 9 | BioNTech SE | 26.78 Bn | 8.39 Bn | 668.28 Mn | -0.72 |
| 10 | Pyxis Oncology | 199.01 Mn | 166.02 Mn | - | -0.40 |
Historic Data
Download Data| Date | Value |
|---|---|
| Jun 30, 2026 | -0.41 |
| Dec 31, 2025 | -0.30 |
| Sep 30, 2025 | -0.35 |
| Jun 30, 2025 | -0.30 |
| Mar 31, 2025 | -0.37 |
| Dec 31, 2024 | -0.61 |
| Sep 30, 2024 | -0.35 |
| Jun 30, 2024 | -0.29 |
| Mar 31, 2024 | -0.23 |
| Dec 31, 2023 | -0.50 |
| Sep 30, 2023 | -0.58 |
| Jun 30, 2023 | -0.47 |
| Mar 31, 2023 | -0.72 |
| Dec 31, 2022 | -1.07 |
| Sep 30, 2022 | -1.25 |
| Jun 30, 2022 | -1.20 |
| Mar 31, 2022 | -0.98 |
| Dec 31, 2021 | -4.96 |
| Sep 30, 2021 | -29.32 |
| Jun 30, 2021 | -4.03 |