Pyxis Oncology (PYXS) EPS (Basic) (2020 - 2025)

Pyxis Oncology (PYXS) reported EPS (Basic) of -$0.29 for Q4 2025, up 50.85% year-over-year from -$0.19 in Q4 2024, and up 17.14% quarter-over-quarter from -$0.35 in Q3 2025.

Pyxis Oncology (PYXS) EPS (Basic) (2020 - 2025) Analysis & Trends

Pyxis Oncology (PYXS) has 6 years of EPS (Basic) data on file, last reported at -$0.29 in Q4 2025.

  • EPS (Basic) for Q4 2025 came in at -$0.29, up 50.85% year-over-year; the trailing twelve-month figure through Dec 2025 was -$1.29 (changed 0.0% YoY), and the FY2025 annual result was -$1.28, up 3.03% from the prior year.
  • EPS (Basic) grew to -$0.29 in Q4 2025 per PYXS's latest filing, from -$0.35 in the prior quarter.
  • Over five years, EPS (Basic) peaked at $31.32 in Q4 2021 and troughed at -$27.26 in Q1 2021.
  • A 5-year average of -$0.93 and a median of -$0.48 in 2023 frame the typical range for EPS (Basic).
  • The sharpest annual moves came in 2021 and 2025: EPS (Basic) jumped 879.1% in 2021, then plunged 483.33% in 2025.
  • A 5-year view of EPS (Basic) shows it stood at $31.32 in 2021, then slumped by 103.32% to -$1.04 in 2022, then soared by 68.27% to -$0.33 in 2023, then plunged by 78.79% to -$0.59 in 2024, then surged by 50.85% to -$0.29 in 2025.
  • Business Quant data shows PYXS's EPS (Basic) at -$0.29 in Q4 2025, -$0.35 in Q3 2025, and -$0.3 in Q2 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EPS (Basic) (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -0.68
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - 3.06
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn 0.00
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - 0.00
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - 0.00
7 Psyence Biomedical 212.16 Bn 212.16 Bn - 0.00
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 4.06
9 Abivax 91.96 Bn 91.96 Bn - -0.06
10 Pyxis Oncology 125.84 Mn 108.95 Mn 8.65 Mn -0.29

Historic Data

Download Data
DateValue
Dec 31, 2025 -0.29
Sep 30, 2025 -0.35
Jun 30, 2025 -0.30
Mar 31, 2025 -0.35
Dec 31, 2024 -0.59
Sep 30, 2024 -0.35
Jun 30, 2024 -0.29
Mar 31, 2024 -0.06
Dec 31, 2023 -0.33
Sep 30, 2023 -0.56
Jun 30, 2023 -0.41
Mar 31, 2023 -0.54
Dec 31, 2022 -1.04
Sep 30, 2022 -0.85
Jun 30, 2022 -0.79
Mar 31, 2022 -0.97
Dec 31, 2021 31.32
Sep 30, 2021 -8.96
Jun 30, 2021 -5.54
Mar 31, 2021 -27.26