Pyxis Oncology PYXS
NASDAQ PYXS
$3.08 -0.04 (-1.28%)
At close: Aug 21, 2026 · 4:00 PM EDT

Pyxis Oncology (PYXS) Cash & Equivalents (2020 - 2026)

Pyxis Oncology (PYXS) posted quarterly Cash & Equivalents of $15.4 million for Q4 2025, down 20.8% year-over-year from $19.5 million in Q4 2024, and up 72.91% quarter-over-quarter from $8.9 million in Q3 2025.

Pyxis Oncology (PYXS) Cash & Equivalents (2020 - 2026) Analysis & Trends

Pyxis Oncology (PYXS) has reported Cash & Equivalents for 6 consecutive years, with $15.4 million the latest figure, recorded in Q4 2025.

  • In Q4 2025, Cash & Equivalents fell 20.8% year-over-year to $15.4 million; the TTM figure through Dec 2025 stood at $15.4 million (down 20.8% YoY), while the FY2025 annual figure was $15.4 million, down 20.8% from the prior year.
  • Cash & Equivalents grew to $15.4 million in Q4 2025 per PYXS's latest filing, from $8.9 million in the prior quarter.
  • Across five years, Cash & Equivalents topped out at $274.7 million in Q4 2021 and bottomed at $8.9 million in Q3 2025.
  • Historically, Cash & Equivalents has averaged $88.8 million across 5 years, with a median of $26.9 million in 2023.
  • Annual changes were most pronounced in 2021 — Cash & Equivalents soared 1086.88% — and 2023, when it plunged 94.61%.
  • Pyxis Oncology's Cash & Equivalents stood at $274.7 million in 2021, then slumped by 34.74% to $179.3 million in 2022, then slumped by 94.61% to $9.7 million in 2023, then soared by 101.5% to $19.5 million in 2024, then dropped by 20.8% to $15.4 million in 2025.
  • Business Quant data shows PYXS's Cash & Equivalents at $15.4 million in Q4 2025, $8.9 million in Q3 2025, and $10.7 million in Q2 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Cash & Equiv. (Qtr)
1 Vertex Pharmaceuticals 139.13 Bn 131.28 Bn 2.84 Bn 6.14 Bn
2 Regeneron Pharmaceuticals 85.77 Bn 77.77 Bn 3.93 Bn 2.46 Bn
3 Argenx Se 64.64 Bn 59.46 Bn 1.37 Bn 3.58 Bn
4 Moderna 58.29 Bn 53.16 Bn 52.00 Mn 1.72 Bn
5 BeOne Medicines 41.92 Bn 36.82 Bn 1.53 Bn 5.10 Bn
6 Alnylam Pharmaceuticals 31.58 Bn 28.28 Bn 992.69 Mn 1.71 Bn
7 BioNTech SE 28.12 Bn 9.73 Bn 668.28 Mn 8.93 Bn
8 Insmed 27.39 Bn 26.22 Bn 358.27 Mn 544.80 Mn
9 Royalty Pharma 27.27 Bn 26.43 Bn - 811.99 Mn
10 Pyxis Oncology 198.37 Mn 165.38 Mn - 18.86 Mn

Historic Data

Download Data
DateValue
Jun 30, 2026 18.86 Mn
Dec 31, 2025 15.42 Mn
Sep 30, 2025 8.92 Mn
Jun 30, 2025 10.73 Mn
Mar 31, 2025 12.76 Mn
Dec 31, 2024 19.47 Mn
Sep 30, 2024 12.06 Mn
Jun 30, 2024 25.07 Mn
Mar 31, 2024 27.97 Mn
Dec 31, 2023 9.66 Mn
Sep 30, 2023 14.72 Mn
Jun 30, 2023 25.90 Mn
Mar 31, 2023 53.06 Mn
Dec 31, 2022 179.29 Mn
Sep 30, 2022 198.54 Mn
Jun 30, 2022 223.36 Mn
Mar 31, 2022 247.09 Mn
Dec 31, 2021 274.74 Mn
Sep 30, 2021 133.48 Mn
Jun 30, 2021 142.47 Mn