Protagonist Therapeutics (PTGX) Return on Sales (2017 - 2025)

Protagonist Therapeutics (PTGX) has disclosed Return on Sales for 9 consecutive years, with 11.49% as the latest value for Q4 2025.

  • Quarterly Return on Sales rose 1069.0% to 11.49% in Q4 2025 from the year-ago period, while the trailing twelve-month figure was 0.01% through Dec 2025, down 65.0% year-over-year, with the annual reading at 0.01% for FY2025, 64.0% down from the prior year.
  • Return on Sales hit 11.49% in Q4 2025 for Protagonist Therapeutics, up from 8.35% in the prior quarter.
  • In the past five years, Return on Sales ranged from a high of 11.49% in Q4 2025 to a low of 45.51% in Q2 2022.
  • Historically, Return on Sales has averaged 3.73% across 5 years, with a median of 1.23% in 2023.
  • Biggest five-year swings in Return on Sales: plummeted -10654bps in 2021 and later soared 4429bps in 2023.
  • Year by year, Return on Sales stood at 10.32% in 2021, then plummeted by -103bps to 0.3% in 2022, then surged by 997bps to 2.73% in 2023, then plummeted by -71bps to 0.8% in 2024, then skyrocketed by 1339bps to 11.49% in 2025.
  • Business Quant data shows Return on Sales for PTGX at 11.49% in Q4 2025, 8.35% in Q3 2025, and 6.27% in Q2 2025.