Protagonist Therapeutics (PTGX) Return on Sales (2017 - 2026)

Protagonist Therapeutics (PTGX) reported Return on Sales of 0.0% for Q1 2026, little changed on a YoY basis from 0.0% in Q1 2025, and up 101.12% sequentially from 0.06% in Q4 2025.

Protagonist Therapeutics (PTGX) Return on Sales (2017 - 2026) Analysis & Trends

Protagonist Therapeutics (PTGX) has 10 years of Return on Sales data on file, last reported at 0.0% in Q1 2026.

  • For the quarter ending Q1 2026, Return on Sales changed 0.0% year-over-year to 0.0%; the trailing twelve-month figure through Mar 2026 stood at 0.02% (down 2.0% YoY), and the FY2025 full-year result was 0.03%, down 3.0% from the prior year.
  • Return on Sales rose to 0.0% in Q1 2026, from 0.06% in the prior quarter.
  • In the past five years, Return on Sales ranged from a high of 0.01% in Q4 2023 to a low of 1.69% in Q1 2023.
  • A 5-year average of 0.18% and a median of 0.06% in 2025 frame the typical range for Return on Sales.
  • Across the five-year window, Return on Sales tumbled 166 bps in 2023 and jumped 169 bps in 2024, its largest moves.
  • Tracing PTGX's Return on Sales over 5 years: stood at 0.07% in 2022, then jumped by 113 bps to 0.01% in 2023, then fell by 9 bps to 0.01% in 2024, then slumped by 848 bps to 0.06% in 2025, then surged by 101 bps to 0.0% in 2026.
  • Business Quant data shows PTGX's Return on Sales at 0.0% in Q1 2026, 0.06% in Q4 2025, and 0.08% in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROS (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 0.00%
4 NuCana 279.75 Bn 279.75 Bn - -
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 0.00%
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 0.00%
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn 0.00%
9 Revolution Medicines 37.78 Bn 37.78 Bn - -
10 Protagonist Therapeutics 8.81 Bn 8.81 Bn - 0.00%

Historic Data

Download Data
DateValue
Mar 31, 2026 0.00%
Dec 31, 2025 -0.06%
Sep 30, 2025 -0.08%
Jun 30, 2025 -0.06%
Mar 31, 2025 0.00%
Dec 31, 2024 0.01%
Sep 30, 2024 -0.07%
Jun 30, 2024 -0.07%
Mar 31, 2024 0.01%
Dec 31, 2023 0.01%
Mar 31, 2023 -1.69%
Dec 31, 2022 -0.07%
Sep 30, 2022 -0.05%
Jun 30, 2022 -0.50%
Mar 31, 2022 -0.03%
Dec 31, 2021 -0.04%
Sep 30, 2021 -0.03%
Jun 30, 2021 -0.14%
Mar 31, 2021 -0.04%
Dec 31, 2020 -0.03%