Protagonist Therapeutics (PTGX) Return on Invested Capital (2018 - 2025)

Protagonist Therapeutics' Return on Invested Capital history spans 6 years, with the latest figure at 0.25% for Q4 2025.

  • For Q4 2025, Return on Invested Capital fell 67.0% year-over-year to 0.25%; the TTM value through Dec 2025 reached 0.25%, down 67.0%, while the annual FY2025 figure was 0.25%, 74.0% down from the prior year.
  • Return on Invested Capital for Q4 2025 was 0.25% at Protagonist Therapeutics, down from 0.03% in the prior quarter.
  • Across five years, Return on Invested Capital topped out at 0.49% in Q1 2024 and bottomed at 0.26% in Q2 2021.
  • The 3-year median for Return on Invested Capital is 0.04% (2025), against an average of 0.12%.
  • The largest annual shift saw Return on Invested Capital skyrocketed 94bps in 2021 before it tumbled -67bps in 2025.
  • A 3-year view of Return on Invested Capital shows it stood at 0.26% in 2021, then skyrocketed by 256bps to 0.41% in 2024, then crashed by -161bps to 0.25% in 2025.
  • Per Business Quant, the three most recent readings for PTGX's Return on Invested Capital are 0.25% (Q4 2025), 0.03% (Q3 2025), and 0.03% (Q2 2025).