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Vertex Pharmaceuticals (VRTX) Return on Invested Capital (2016 - 2025)

Vertex Pharmaceuticals has reported Return on Invested Capital over the past 14 years, most recently at 0.2% for Q4 2025.

  • Quarterly results put Return on Invested Capital at 0.2% for Q4 2025, up 17.0% from a year ago — trailing twelve months through Dec 2025 was 0.2% (up 17.0% YoY), and the annual figure for FY2025 was 0.2%, up 17.0%.
  • Return on Invested Capital for Q4 2025 was 0.2% at Vertex Pharmaceuticals, up from 0.19% in the prior quarter.
  • Over the last five years, Return on Invested Capital for VRTX hit a ceiling of 0.29% in Q2 2022 and a floor of 0.15% in Q1 2025.
  • Median Return on Invested Capital over the past 5 years was 0.2% (2021), compared with a mean of 0.18%.
  • Peak annual rise in Return on Invested Capital hit 17bps in 2025, while the deepest fall reached -34bps in 2025.
  • Vertex Pharmaceuticals' Return on Invested Capital stood at 0.24% in 2021, then rose by 4bps to 0.25% in 2022, then decreased by -26bps to 0.18% in 2023, then tumbled by -83bps to 0.03% in 2024, then soared by 535bps to 0.2% in 2025.
  • The last three reported values for Return on Invested Capital were 0.2% (Q4 2025), 0.19% (Q3 2025), and 0.19% (Q2 2025) per Business Quant data.