Vertex Pharmaceuticals (VRTX) Return on Invested Capital (2012 - 2025)

Vertex Pharmaceuticals' (VRTX) quarterly Return on Invested Capital came in at 0.19% in Q3 2025, up 18.0% year-on-year from 0.16% in Q3 2024, and up 35.01% quarter-over-quarter from 0.14% in Q2 2025.

Vertex Pharmaceuticals (VRTX) Return on Invested Capital (2012 - 2025) Analysis & Trends

Vertex Pharmaceuticals' Return on Invested Capital history runs 12 years deep, the most recent figure standing at 0.19% for Q3 2025.

  • On a quarterly basis, Return on Invested Capital rose 18.0% year-over-year to 0.19% in Q3 2025; TTM through Sep 2025 was 0.19%, a 18.0% increase from a year earlier, with the FY2024 full-year figure at 0.02%, down 5.0% from the prior year.
  • Return on Invested Capital climbed to 0.19% in Q3 2025 per VRTX's latest filing, from 0.14% in the prior quarter.
  • Across five years, Return on Invested Capital topped out at 0.19% in Q3 2025 and bottomed at 0.1% in Q1 2025.
  • The 5-year median for Return on Invested Capital is 0.06% (2022), against an average of 0.05%.
  • Biggest YoY gain for Return on Invested Capital was 18 bps in 2025; the steepest drop was 19 bps in 2025.
  • Year by year, Return on Invested Capital stood at 0.04% in 2021, then jumped by 57 bps to 0.07% in 2022, then grew by 7 bps to 0.07% in 2023, then plunged by 82 bps to 0.01% in 2024, then soared by 1349 bps to 0.19% in 2025.
  • Per Business Quant, the three latest VRTX Return on Invested Capital figures stand at 0.19% (Q3 2025), 0.14% (Q2 2025), and 0.1% (Q1 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROIC (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - -
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn 0.00%
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn -
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn 0.04%
7 Belite Bio 61.40 Bn 61.40 Bn - -
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn -
9 Revolution Medicines 37.37 Bn 37.37 Bn - -
10 Alnylam Pharmaceuticals 36.08 Bn 33.07 Bn 959.66 Mn -

Historic Data

Download Data
DateValue
Sep 30, 2025 0.19%
Jun 30, 2025 0.14%
Mar 31, 2025 -0.10%
Dec 31, 2024 0.01%
Sep 30, 2024 0.01%
Jun 30, 2024 0.02%
Mar 31, 2024 0.08%
Dec 31, 2023 0.07%
Sep 30, 2023 0.07%
Jun 30, 2023 0.07%
Mar 31, 2023 0.07%
Dec 31, 2022 0.07%
Sep 30, 2022 0.06%
Jun 30, 2022 0.06%
Mar 31, 2022 0.05%
Dec 31, 2021 0.04%
Sep 30, 2021 0.04%
Jun 30, 2021 0.03%
Mar 31, 2021 0.04%
Dec 31, 2020 0.04%