Vertex Pharmaceuticals (VRTX) Return on Invested Capital (2012 - 2025)
Vertex Pharmaceuticals' (VRTX) quarterly Return on Invested Capital came in at 0.19% in Q3 2025, up 18.0% year-on-year from 0.16% in Q3 2024, and up 35.01% quarter-over-quarter from 0.14% in Q2 2025.
Vertex Pharmaceuticals (VRTX) Return on Invested Capital (2012 - 2025) Analysis & Trends
Vertex Pharmaceuticals' Return on Invested Capital history runs 12 years deep, the most recent figure standing at 0.19% for Q3 2025.
- On a quarterly basis, Return on Invested Capital rose 18.0% year-over-year to 0.19% in Q3 2025; TTM through Sep 2025 was 0.19%, a 18.0% increase from a year earlier, with the FY2024 full-year figure at 0.02%, down 5.0% from the prior year.
- Return on Invested Capital climbed to 0.19% in Q3 2025 per VRTX's latest filing, from 0.14% in the prior quarter.
- Across five years, Return on Invested Capital topped out at 0.19% in Q3 2025 and bottomed at 0.1% in Q1 2025.
- The 5-year median for Return on Invested Capital is 0.06% (2022), against an average of 0.05%.
- Biggest YoY gain for Return on Invested Capital was 18 bps in 2025; the steepest drop was 19 bps in 2025.
- Year by year, Return on Invested Capital stood at 0.04% in 2021, then jumped by 57 bps to 0.07% in 2022, then grew by 7 bps to 0.07% in 2023, then plunged by 82 bps to 0.01% in 2024, then soared by 1349 bps to 0.19% in 2025.
- Per Business Quant, the three latest VRTX Return on Invested Capital figures stand at 0.19% (Q3 2025), 0.14% (Q2 2025), and 0.1% (Q1 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROIC (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 67,072.09 Bn | 67,072.09 Bn | - | - |
| 2 | Nanobiotix | 1,894.61 Bn | 1,894.55 Bn | - | - |
| 3 | Akari Therapeutics | 1,014.18 Bn | 1,014.18 Bn | - | - |
| 4 | BeOne Medicines | 471.64 Bn | 466.85 Bn | 1.35 Bn | 0.00% |
| 5 | Vertex Pharmaceuticals | 121.72 Bn | 114.47 Bn | 2.59 Bn | - |
| 6 | Regeneron Pharmaceuticals | 68.28 Bn | 59.52 Bn | 3.31 Bn | 0.04% |
| 7 | Belite Bio | 61.40 Bn | 61.40 Bn | - | - |
| 8 | Argenx Se | 56.94 Bn | 56.94 Bn | 1.18 Bn | - |
| 9 | Revolution Medicines | 37.37 Bn | 37.37 Bn | - | - |
| 10 | Alnylam Pharmaceuticals | 36.08 Bn | 33.07 Bn | 959.66 Mn | - |
Historic Data
Download Data| Date | Value |
|---|---|
| Sep 30, 2025 | 0.19% |
| Jun 30, 2025 | 0.14% |
| Mar 31, 2025 | -0.10% |
| Dec 31, 2024 | 0.01% |
| Sep 30, 2024 | 0.01% |
| Jun 30, 2024 | 0.02% |
| Mar 31, 2024 | 0.08% |
| Dec 31, 2023 | 0.07% |
| Sep 30, 2023 | 0.07% |
| Jun 30, 2023 | 0.07% |
| Mar 31, 2023 | 0.07% |
| Dec 31, 2022 | 0.07% |
| Sep 30, 2022 | 0.06% |
| Jun 30, 2022 | 0.06% |
| Mar 31, 2022 | 0.05% |
| Dec 31, 2021 | 0.04% |
| Sep 30, 2021 | 0.04% |
| Jun 30, 2021 | 0.03% |
| Mar 31, 2021 | 0.04% |
| Dec 31, 2020 | 0.04% |