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Asset Utilization RatioAssets AverageDebt RatioDebt to EquityEBIT MarginEBITDA MarginEBT MarginEnterprise ValueEquity AverageEquity RatioFCF MarginGross MarginInterest Coverage RatioInventory AverageInvested CapitalNet MarginOperating MarginReturn on AssetsReturn on Capital EmployedReturn on EquityReturn on Invested CapitalReturn on SalesTimes Interest Earned

Personalis (PSNL) Operating Margin (2018 - 2025)

Personalis has reported Operating Margin over the past 8 years, most recently at 263.64% for Q4 2025.

  • Quarterly results put Operating Margin at 263.64% for Q4 2025, up 37145.0% from a year ago — trailing twelve months through Dec 2025 was 24.5% (up 5618.0% YoY), and the annual figure for FY2025 was 24.5%, up 5618.0%.
  • Operating Margin for Q4 2025 was 263.64% at Personalis, up from 160.68% in the prior quarter.
  • Over the last five years, Operating Margin for PSNL hit a ceiling of 263.64% in Q4 2025 and a floor of 191.87% in Q4 2022.
  • Median Operating Margin over the past 5 years was 114.82% (2023), compared with a mean of 103.28%.
  • Biggest five-year swings in Operating Margin: plummeted -12608bps in 2022 and later surged 37145bps in 2025.
  • Personalis' Operating Margin stood at 97.79% in 2021, then plummeted by -96bps to 191.87% in 2022, then surged by 36bps to 121.84% in 2023, then grew by 12bps to 107.81% in 2024, then skyrocketed by 345bps to 263.64% in 2025.
  • The last three reported values for Operating Margin were 263.64% (Q4 2025), 160.68% (Q3 2025), and 126.75% (Q2 2025) per Business Quant data.