Growth Metrics

Personalis (PSNL) Operating Margin (2018 - 2025)

Personalis (PSNL) has 8 years of Operating Margin data on record, last reported at 263.64% in Q4 2025.

  • For Q4 2025, Operating Margin rose 6669.0% year-over-year to 263.64%; the TTM value through Dec 2025 reached 24.5%, down 433.0%, while the annual FY2025 figure was 24.5%, 433.0% down from the prior year.
  • Operating Margin reached 263.64% in Q4 2025 per PSNL's latest filing, up from 160.68% in the prior quarter.
  • Across five years, Operating Margin topped out at 263.64% in Q4 2025 and bottomed at 191.87% in Q4 2022.
  • Average Operating Margin over 5 years is 88.04%, with a median of 109.82% recorded in 2021.
  • Peak YoY movement for Operating Margin: tumbled -12608bps in 2022, then soared 31880bps in 2024.
  • A 5-year view of Operating Margin shows it stood at 97.79% in 2021, then crashed by -96bps to 191.87% in 2022, then skyrocketed by 36bps to 121.84% in 2023, then skyrocketed by 262bps to 196.96% in 2024, then skyrocketed by 34bps to 263.64% in 2025.
  • Per Business Quant database, its latest 3 readings for Operating Margin were 263.64% in Q4 2025, 160.68% in Q3 2025, and 126.75% in Q2 2025.