Personalis (PSNL) Operating Margin (2018 - 2026)
Personalis (PSNL) posted quarterly Operating Margin of 207.87% for Q1 2026, down 12198.0% year-over-year from N/an in Q1 2025, and down 42.7% on a QoQ basis from 145.67% in Q4 2025.
Personalis (PSNL) Operating Margin (2018 - 2026) Analysis & Trends
Personalis (PSNL) has reported Operating Margin for 9 consecutive years, with 207.87% the latest figure, recorded in Q1 2026.
- In Q1 2026, Operating Margin fell 12198.0% year-over-year to 207.87%; the TTM figure through Mar 2026 stood at 158.91% (down 8063.0% YoY), while the FY2025 annual figure was 126.43%, down 4575.0% from the prior year.
- Operating Margin came in at 207.87% for Q1 2026 at Personalis, down from 145.67% in the prior quarter.
- The five-year high for Operating Margin was 55.94% in Q3 2024, with the low at 207.87% in Q1 2026.
- Average Operating Margin over 5 years is 139.81%, with a median of 151.78% recorded in 2023.
- Across the five-year window, Operating Margin slumped 12608 bps in 2022 and surged 11282 bps in 2024, its largest moves.
- Year by year, Operating Margin stood at 191.87% in 2022, then jumped by 36 bps to 121.84% in 2023, then climbed by 12 bps to 107.81% in 2024, then plunged by 35 bps to 145.67% in 2025, then sank by 43 bps to 207.87% in 2026.
- According to Business Quant data, Operating Margin over the past three periods registered 207.87%, 145.67%, and 160.68% for Q1 2026, Q4 2025, and Q3 2025 respectively.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Waters | 31,055.11 Bn | 31,054.65 Bn | 1.11 Bn | -3.71% |
| 2 | Thermo Fisher Scientific | 191.02 Bn | 187.77 Bn | 7.74 Bn | 16.93% |
| 3 | Danaher | 137.16 Bn | 131.47 Bn | 3.59 Bn | 22.58% |
| 4 | Idexx Laboratories | 42.82 Bn | 42.62 Bn | 722.74 Mn | 31.78% |
| 5 | Natera | 39.09 Bn | 37.99 Bn | 696.04 Mn | -13.42% |
| 6 | Agilent Technologies | 37.61 Bn | 35.81 Bn | 990.00 Mn | 21.74% |
| 7 | Iqvia Holdings | 34.23 Bn | 32.25 Bn | 1.36 Bn | 12.38% |
| 8 | Illumina | 28.14 Bn | 26.98 Bn | 721.00 Mn | 19.16% |
| 9 | Mettler Toledo International | 26.40 Bn | 26.33 Bn | 555.82 Mn | 25.23% |
| 10 | Personalis | 1.44 Bn | 1.20 Bn | 281,000.00 | -207.87% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -207.87% |
| Dec 31, 2025 | -145.67% |
| Sep 30, 2025 | -160.68% |
| Jun 30, 2025 | -126.75% |
| Mar 31, 2025 | -85.88% |
| Dec 31, 2024 | -107.81% |
| Sep 30, 2024 | -55.94% |
| Jun 30, 2024 | -74.81% |
| Mar 31, 2024 | -96.70% |
| Dec 31, 2023 | -121.84% |
| Sep 30, 2023 | -168.76% |
| Jun 30, 2023 | -151.78% |
| Mar 31, 2023 | -158.14% |
| Dec 31, 2022 | -191.87% |
| Sep 30, 2022 | -183.46% |
| Jun 30, 2022 | -152.86% |
| Mar 31, 2022 | -185.89% |
| Dec 31, 2021 | -97.79% |
| Sep 30, 2021 | -79.47% |
| Jun 30, 2021 | -68.98% |