Prothena Corp Public (PRTA) Operating Margin (2013 - 2026)
Prothena Corp Public (PRTA) recorded Operating Margin of -2089.21% in Q2 2026, down 174.82 percentage points from -1914.39% a year earlier and down 2148.00 percentage points from the prior quarter.
Prothena Corp Public (PRTA) Operating Margin (2013 - 2026) Analysis & Trends
On a TTM basis, Prothena Corp Public's Operating Margin came in at -101.80% as of Jun 30, 2026, up 2621.41 percentage points year-over-year; for FY2025, it came in at -2216.44%, down 2102.08 percentage points from FY2024.
- Annual Operating Margin has a five-year change of +10999.74 percentage points (FY2020 to FY2025).
- Across earlier years, Operating Margin came in at -114.36% in FY2024 (+94.72 pp), -209.08% in FY2023 (+34.97 pp), -244.05% in FY2022 (-279.94 pp) and 35.88% in FY2021 (+13252.06 pp).
- Quarterly Operating Margin has ranged from -163056.00% in Q1 2024 to 78.48% in Q3 2021 over the past five years.
- On a year-over-year basis, Operating Margin rose in four of the last eight quarters, with an average year-over-year change of +8612.14 percentage points.
- Peak year-over-year performance for Operating Margin in the last five years was a gain of 160737.01 percentage points in Q1 2025, against a drop of 160459.18 percentage points in Q1 2024 at the low end.
- Per Business Quant, the preceding three quarters came in at 58.80% (Q1 2026), -115252.38% (Q4 2025) and -1666.25% (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Operating Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 655.56 Bn | 574.09 Bn | 17.26 Bn | 28.21% |
| 2 | AbbVie | 470.94 Bn | 444.10 Bn | 12.70 Bn | 37.86% |
| 3 | Merck | 367.14 Bn | 321.57 Bn | 12.21 Bn | -3.52% |
| 4 | Novartis Ag | 280.33 Bn | 236.20 Bn | 11.24 Bn | 32.97% |
| 5 | Astrazeneca | 257.78 Bn | 231.34 Bn | 12.86 Bn | 20.57% |
| 6 | Amgen | 226.04 Bn | 181.44 Bn | 7.24 Bn | 34.95% |
| 7 | Gilead Sciences | 188.89 Bn | 163.01 Bn | 6.22 Bn | -133.21% |
| 8 | Pfizer | 163.75 Bn | 110.70 Bn | 10.94 Bn | 28.37% |
| 9 | Vertex Pharmaceuticals | 133.68 Bn | 105.69 Bn | 2.84 Bn | 37.40% |
| 10 | Prothena Corp Public | 451.21 Mn | -804.86 Mn | - | -2,089.21% |
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -2,089.21% |
| Mar 31, 2026 | 58.80% |
| Dec 31, 2025 | -115,252.38% |
| Sep 30, 2025 | -1,666.25% |
| Jun 30, 2025 | -1,914.39% |
| Mar 31, 2025 | -2,318.99% |
| Dec 31, 2024 | -3,056.85% |
| Sep 30, 2024 | -6,857.01% |
| Jun 30, 2024 | 44.22% |
| Mar 31, 2024 | -163,056.00% |
| Dec 31, 2023 | -24,846.52% |
| Sep 30, 2023 | 12.15% |
| Jun 30, 2023 | -1,654.74% |
| Mar 31, 2023 | -2,596.82% |
| Dec 31, 2022 | -0.14% |
| Sep 30, 2022 | -3,317.86% |
| Jun 30, 2022 | -3,293.37% |
| Mar 31, 2022 | -3,290.89% |
| Dec 31, 2021 | -2,823.55% |
| Sep 30, 2021 | 78.48% |
Prothena Corp Public Operating Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=operating-margin&ticker=PRTA&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "operating-margin", "ticker": "PRTA", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=operating-margin&ticker=PRTA&period=max&api_key=YOUR_API_KEY");
const data = await res.json();