Prime Medicine (PRME) Return on Sales [ROS] (2024 - 2026)
Prime Medicine (PRME) posted Return on Sales [ROS] of -3750.87% for Q2 2026, up 1036.31 percentage points from -4787.17% a year earlier and up 2166.66 percentage points from the prior quarter.
Prime Medicine (PRME) Return on Sales [ROS] (2024 - 2026) Analysis & Trends
For the trailing twelve months through Jun 30, 2026, Return on Sales [ROS] at Prime Medicine was -4824.94%, down 708.38 percentage points year-over-year; for FY2025, it was -4498.06%, up 2289.30 percentage points from FY2024.
- Annual Return on Sales [ROS] shows a five-year change of -4480.17 percentage points (FY2020 to FY2025).
- In prior years, Prime Medicine's Return on Sales [ROS] was -6787.36% in FY2024.
- The Q2 2026 figure stands as the highest quarterly Return on Sales [ROS] since Q1 2025.
- On a year-over-year basis, Return on Sales [ROS] increased in four of the last six quarters, with an average year-over-year change of +9016.43 percentage points.
- According to Business Quant data, Return on Sales [ROS] for the three prior quarters was -5917.52% (Q1 2026), -5800.48% (Q4 2025) and -4405.96% (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROS (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,076.25 Bn | 1,044.84 Bn | 19.71 Bn | 51.16% |
| 2 | Johnson & Johnson | 617.18 Bn | 535.70 Bn | 17.26 Bn | 28.21% |
| 3 | AbbVie | 464.58 Bn | 437.73 Bn | 12.70 Bn | 37.86% |
| 4 | Merck | 356.04 Bn | 310.47 Bn | 12.21 Bn | -3.52% |
| 5 | Novartis Ag | 269.07 Bn | 224.94 Bn | 11.24 Bn | 32.97% |
| 6 | Astrazeneca | 243.21 Bn | 216.77 Bn | 12.86 Bn | 20.57% |
| 7 | Amgen | 217.88 Bn | 173.28 Bn | 7.24 Bn | 34.95% |
| 8 | Gilead Sciences | 179.62 Bn | 153.74 Bn | 6.22 Bn | -133.21% |
| 9 | Pfizer | 158.45 Bn | 105.40 Bn | 10.94 Bn | 28.37% |
| 10 | Prime Medicine | 538.60 Mn | 538.60 Mn | - | -3,750.87% |
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -3,750.87% |
| Mar 31, 2026 | -5,917.52% |
| Dec 31, 2025 | -5,800.48% |
| Sep 30, 2025 | -4,405.96% |
| Jun 30, 2025 | -4,787.17% |
| Mar 31, 2025 | -3,603.30% |
| Dec 31, 2024 | -2,025.74% |
| Sep 30, 2024 | -25,948.33% |
| Jun 30, 2024 | -37,819.80% |
| Mar 31, 2024 | -8,179.53% |
Prime Medicine Return on Sales [ROS] API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=return-on-sales-%5Bros%5D&ticker=PRME&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "return-on-sales-[ros]", "ticker": "PRME", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=return-on-sales-%5Bros%5D&ticker=PRME&period=max&api_key=YOUR_API_KEY");
const data = await res.json();