Prime Medicine (PRME) Return on Assets [ROA] (2022 - 2026)
Prime Medicine's Return on Assets [ROA] was -70.80% in Q2 2026, down 5.16 percentage points from -65.64% a year earlier and down 7.24 percentage points from the prior quarter.
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Analysis
Prime Medicine (PRME) Return on Assets [ROA] (2022 - 2026) Analysis & Trends
For FY2025, Return on Assets [ROA] at Prime Medicine came in at -63.79%, up 15.94 percentage points from FY2024.
- Return on Assets [ROA] shows a three-year change of -26.99 percentage points (FY2022 to FY2025).
- In earlier years, Return on Assets [ROA] was -79.73% in FY2024 (-8.22 pp), -71.51% in FY2023 (-34.71 pp) and -36.79% in FY2022.
- The Q2 2026 figure marks the lowest quarterly Return on Assets [ROA] since Q3 2024.
- Compared with a year earlier, Return on Assets [ROA] was higher in six of the last eight quarters, with an average year-over-year change of +7.99 percentage points.
- The best year-over-year quarter for Return on Assets [ROA] over five years was Q4 2024 (a gain of 29.36 percentage points); the worst was Q4 2023 (a drop of 49.19 percentage points).
- Per Business Quant data, PRME's Return on Assets [ROA] in the three quarters before Q2 2026 was -63.56% (Q1 2026), -56.29% (Q4 2025) and -60.12% (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROA (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,348.13 Bn | 1,321.74 Bn | 20.46 Bn | 19.00% |
| 2 | Johnson & Johnson | 675.90 Bn | 595.76 Bn | 17.30 Bn | 8.08% |
| 3 | AbbVie | 519.45 Bn | 487.50 Bn | 13.12 Bn | 7.32% |
| 4 | Merck | 364.95 Bn | 327.95 Bn | 13.19 Bn | 1.87% |
| 5 | Novartis Ag | 311.58 Bn | 285.16 Bn | - | - |
| 6 | Astrazeneca | 289.34 Bn | 262.94 Bn | 13.26 Bn | 9.36% |
| 7 | Amgen | 251.64 Bn | 203.30 Bn | 7.58 Bn | 9.80% |
| 8 | Gilead Sciences | 212.05 Bn | 187.07 Bn | 6.73 Bn | -7.67% |
| 9 | Pfizer | 167.35 Bn | 115.00 Bn | 12.56 Bn | 2.00% |
| 10 | Prime Medicine | 704.88 Mn | 469.45 Mn | - | -71.52% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -71.52% |
| Mar 31, 2026 | -64.08% |
| Sep 30, 2025 | -59.43% |
| Jun 30, 2025 | -65.62% |
| Mar 31, 2025 | -64.55% |
| Dec 31, 2024 | -62.15% |
| Sep 30, 2024 | -73.95% |
| Jun 30, 2024 | -76.08% |
| Mar 31, 2024 | -80.91% |
| Dec 31, 2023 | -91.35% |
| Sep 30, 2023 | -65.95% |
| Jun 30, 2023 | -50.36% |
| Mar 31, 2023 | -40.62% |
| Dec 31, 2022 | -42.45% |
API Access
Prime Medicine Return on Assets [ROA] API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=return-on-assets-%5Broa%5D&ticker=PRME&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "return-on-assets-[roa]", "ticker": "PRME", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=return-on-assets-%5Broa%5D&ticker=PRME&period=max&api_key=YOUR_API_KEY");
const data = await res.json();