Prime Medicine (PRME) Return on Assets [ROA] (2022 - 2026)
Prime Medicine's Return on Assets [ROA] was -70.80% in Q2 2026, down 5.16 percentage points from -65.64% a year earlier and down 7.24 percentage points from the prior quarter.
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Analysis
Prime Medicine (PRME) Return on Assets [ROA] (2022 - 2026) Analysis & Trends
For FY2025, Return on Assets [ROA] at Prime Medicine came in at -63.79%, up 15.94 percentage points from FY2024.
- Return on Assets [ROA] shows a three-year change of -26.99 percentage points (FY2022 to FY2025).
- In earlier years, Return on Assets [ROA] was -79.73% in FY2024 (-8.22 pp), -71.51% in FY2023 (-34.71 pp) and -36.79% in FY2022.
- The Q2 2026 figure marks the lowest quarterly Return on Assets [ROA] since Q3 2024.
- Compared with a year earlier, Return on Assets [ROA] was higher in six of the last eight quarters, with an average year-over-year change of +7.99 percentage points.
- The best year-over-year quarter for Return on Assets [ROA] over five years was Q4 2024 (a gain of 29.36 percentage points); the worst was Q4 2023 (a drop of 49.19 percentage points).
- Per Business Quant data, PRME's Return on Assets [ROA] in the three quarters before Q2 2026 was -63.56% (Q1 2026), -56.29% (Q4 2025) and -60.12% (Q3 2025).
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROA (Qtr) |
|---|---|---|---|---|---|
| 1 | Johnson & Johnson | 638.12 Bn | 556.64 Bn | 17.26 Bn | 10.47% |
| 2 | AbbVie | 462.60 Bn | 435.75 Bn | 12.70 Bn | 4.65% |
| 3 | Merck | 358.70 Bn | 313.13 Bn | 12.21 Bn | 2.45% |
| 4 | Novartis Ag | 272.16 Bn | 228.03 Bn | 11.24 Bn | 28.37% |
| 5 | Astrazeneca | 250.36 Bn | 223.92 Bn | 12.86 Bn | 9.10% |
| 6 | Amgen | 227.87 Bn | 183.27 Bn | 7.24 Bn | 9.29% |
| 7 | Gilead Sciences | 184.97 Bn | 159.08 Bn | 6.22 Bn | -6.13% |
| 8 | Pfizer | 162.61 Bn | 109.56 Bn | 10.94 Bn | 2.14% |
| 9 | Vertex Pharmaceuticals | 132.45 Bn | 104.46 Bn | 2.84 Bn | 16.34% |
| 10 | Prime Medicine | 553.06 Mn | 553.06 Mn | - | -70.80% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -70.80% |
| Mar 31, 2026 | -63.56% |
| Dec 31, 2025 | -56.29% |
| Sep 30, 2025 | -60.12% |
| Jun 30, 2025 | -65.64% |
| Mar 31, 2025 | -64.57% |
| Dec 31, 2024 | -62.16% |
| Sep 30, 2024 | -74.01% |
| Jun 30, 2024 | -76.15% |
| Mar 31, 2024 | -80.95% |
| Dec 31, 2023 | -91.52% |
| Sep 30, 2023 | -66.07% |
| Jun 30, 2023 | -50.32% |
| Mar 31, 2023 | -40.57% |
| Dec 31, 2022 | -42.33% |
API Access
Prime Medicine Return on Assets [ROA] API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=return-on-assets-%5Broa%5D&ticker=PRME&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "return-on-assets-[roa]", "ticker": "PRME", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=return-on-assets-%5Broa%5D&ticker=PRME&period=max&api_key=YOUR_API_KEY");
const data = await res.json();