Prelude Therapeutics PRLD
NASDAQ PRLD
$5.43 +0.18 (+3.43%)
As of: Sep 4, 2026 · 12:48 PM EDT

Prelude Therapeutics (PRLD) Research & Development (2019 - 2026)

Prelude Therapeutics (PRLD) posted Research & Development of $13.6 million for Q1 2026, down 24.41% sequentially from $18.0 million in Q4 2025, and down 52.8% YoY from $28.8 million in Q1 2025.

Analysis

Prelude Therapeutics (PRLD) Research & Development (2019 - 2026) Analysis & Trends

Prelude Therapeutics has reported Research & Development for 8 years, with the latest figure at $13.6 million in Q1 2026.

  • Quarterly Research & Development fell 52.8% year-over-year to $13.6 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was $79.1 million (down 33.77% YoY) and the FY2025 annual result came in at $94.3 million, down 20.08% from the prior year.
  • Research & Development slipped to $13.6 million in Q1 2026 per PRLD's latest filing, from $18.0 million in the prior quarter.
  • Over five years, Research & Development peaked at $31.6 million in Q4 2024 and troughed at $13.6 million in Q1 2026.
  • A 5-year average of $24.8 million and a median of $25.8 million in 2025 frame the typical range for Research & Development.
  • The sharpest annual moves came in 2022 and 2026: Research & Development surged 38.56% in 2022, then plunged 52.8% in 2026.
  • Over 5 years, Research & Development stood at $25.9 million in 2022, then grew by 17.25% to $30.3 million in 2023, then gained by 4.25% to $31.6 million in 2024, then tumbled by 43.1% to $18.0 million in 2025, then declined by 24.41% to $13.6 million in 2026.
  • According to Business Quant data, Research & Development over the past three periods registered $13.6 million, $18.0 million, and $21.7 million for Q1 2026, Q4 2025, and Q3 2025 respectively.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) R&D (Qtr)
1 Vertex Pharmaceuticals 139.76 Bn 131.91 Bn 2.84 Bn 993.80 Mn
2 Regeneron Pharmaceuticals 85.72 Bn 77.72 Bn 3.93 Bn 1.63 Bn
3 Argenx Se 63.56 Bn 58.38 Bn 1.37 Bn -486.00 Mn
4 Moderna 57.87 Bn 52.73 Bn 52.00 Mn 651.00 Mn
5 Revolution Medicines 44.06 Bn 44.06 Bn - 394.92 Mn
6 BeOne Medicines 40.08 Bn 34.98 Bn 1.53 Bn 612.28 Mn
7 Alnylam Pharmaceuticals 35.50 Bn 32.20 Bn 992.69 Mn 413.13 Mn
8 Royalty Pharma 28.54 Bn 27.70 Bn - 97.90 Mn
9 Insmed 27.49 Bn 26.33 Bn 358.27 Mn 210.03 Mn
10 Prelude Therapeutics 535.23 Mn 254.61 Mn - 16.13 Mn
Historic Data

Historic Data

Download Data
DateValue
Jun 30, 2026 16.13 Mn
Mar 31, 2026 13.60 Mn
Dec 31, 2025 17.99 Mn
Sep 30, 2025 21.71 Mn
Jun 30, 2025 25.78 Mn
Mar 31, 2025 28.82 Mn
Dec 31, 2024 31.62 Mn
Sep 30, 2024 29.46 Mn
Jun 30, 2024 29.51 Mn
Mar 31, 2024 27.41 Mn
Dec 31, 2023 30.33 Mn
Sep 30, 2023 26.26 Mn
Jun 30, 2023 24.97 Mn
Mar 31, 2023 21.83 Mn
Dec 31, 2022 25.87 Mn
Sep 30, 2022 22.89 Mn
Jun 30, 2022 21.31 Mn
Mar 31, 2022 22.82 Mn
Dec 31, 2021 25.18 Mn
Sep 30, 2021 22.72 Mn