Prelude Therapeutics (PRLD) Research & Development (2019 - 2026)

Prelude Therapeutics (PRLD) reported Research & Development of $13.6 million for Q1 2026, down 52.8% on a YoY basis from $28.8 million in Q1 2025, and down 24.41% sequentially from $18.0 million in Q4 2025.

Prelude Therapeutics (PRLD) Research & Development (2019 - 2026) Analysis & Trends

Prelude Therapeutics (PRLD) has 8 years of Research & Development data on file, last reported at $13.6 million in Q1 2026.

  • For the quarter ending Q1 2026, Research & Development fell 52.8% year-over-year to $13.6 million; the trailing twelve-month figure through Mar 2026 stood at $79.1 million (down 33.77% YoY), and the FY2025 full-year result was $94.3 million, down 20.08% from the prior year.
  • Research & Development slipped to $13.6 million in Q1 2026, from $18.0 million in the prior quarter.
  • In the past five years, Research & Development ranged from a high of $31.6 million in Q4 2024 to a low of $13.6 million in Q1 2026.
  • A 5-year average of $24.8 million and a median of $25.8 million in 2025 frame the typical range for Research & Development.
  • Across the five-year window, Research & Development soared 38.56% in 2022 and slumped 52.8% in 2026, its largest moves.
  • Tracing PRLD's Research & Development over 5 years: stood at $25.9 million in 2022, then gained by 17.25% to $30.3 million in 2023, then grew by 4.25% to $31.6 million in 2024, then plunged by 43.1% to $18.0 million in 2025, then decreased by 24.41% to $13.6 million in 2026.
  • Business Quant data shows PRLD's Research & Development at $13.6 million in Q1 2026, $18.0 million in Q4 2025, and $21.7 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) R&D (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -17.94 Mn
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 541.22 Mn
4 NuCana 279.75 Bn 279.75 Bn - -2.31 Mn
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 961.60 Mn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 1.54 Bn
7 Belite Bio 62.51 Bn 62.51 Bn - 15.66 Mn
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn 1.37 Bn
9 Revolution Medicines 37.78 Bn 37.78 Bn - 343.97 Mn
10 Prelude Therapeutics 324.30 Mn 179.71 Mn - 13.60 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 13.60 Mn
Dec 31, 2025 17.99 Mn
Sep 30, 2025 21.71 Mn
Jun 30, 2025 25.78 Mn
Mar 31, 2025 28.82 Mn
Dec 31, 2024 31.62 Mn
Sep 30, 2024 29.46 Mn
Jun 30, 2024 29.51 Mn
Mar 31, 2024 27.41 Mn
Dec 31, 2023 30.33 Mn
Sep 30, 2023 26.26 Mn
Jun 30, 2023 24.97 Mn
Mar 31, 2023 21.83 Mn
Dec 31, 2022 25.87 Mn
Sep 30, 2022 22.89 Mn
Jun 30, 2022 21.31 Mn
Mar 31, 2022 22.82 Mn
Dec 31, 2021 25.18 Mn
Sep 30, 2021 22.72 Mn
Jun 30, 2021 22.41 Mn