Prelude Therapeutics (PRLD) Research & Development (2019 - 2026)

Prelude Therapeutics' (PRLD) quarterly Research & Development came in at $13.6 million in Q1 2026, down 52.8% year-on-year from $28.8 million in Q1 2025, and down 24.41% quarter-over-quarter from $18.0 million in Q4 2025.

Prelude Therapeutics (PRLD) Research & Development (2019 - 2026) Analysis & Trends

Prelude Therapeutics has disclosed Research & Development across 8 years of filings, most recently posting $13.6 million for Q1 2026.

  • Research & Development for Q1 2026 came in at $13.6 million, down 52.8% year-over-year; the trailing twelve-month figure through Mar 2026 was $79.1 million (down 33.77% YoY), and the FY2025 annual result was $94.3 million, down 20.08% from the prior year.
  • Research & Development came in at $13.6 million for Q1 2026 at Prelude Therapeutics, down from $18.0 million in the prior quarter.
  • In the past five years, Research & Development ranged from a high of $31.6 million in Q4 2024 to a low of $13.6 million in Q1 2026.
  • The 5-year median for Research & Development is $25.8 million (2025), against an average of $24.8 million.
  • Across the five-year window, Research & Development soared 38.56% in 2022 and plunged 52.8% in 2026, its largest moves.
  • Prelude Therapeutics' Research & Development stood at $25.9 million in 2022, then advanced by 17.25% to $30.3 million in 2023, then increased by 4.25% to $31.6 million in 2024, then tumbled by 43.1% to $18.0 million in 2025, then slipped by 24.41% to $13.6 million in 2026.
  • The last three Research & Development figures came in at $13.6 million (Q1 2026), $18.0 million (Q4 2025), and $21.7 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) R&D (Qtr)
1 Alterity Therapeutics 723,416.35 Bn 723,416.32 Bn - 4.32 Mn
2 Belite Bio 57,340.00 Bn 57,340.00 Bn - 15.66 Mn
3 Quantum Biopharma 19,125.08 Bn 19,125.08 Bn - 626,092.00
4 Legend Biotech 3,262.00 Bn 3,261.71 Bn 242.10 Mn -101.30 Mn
5 Akari Therapeutics 1,789.67 Bn 1,789.67 Bn - 1.46 Mn
6 Evaxion A 1,480.39 Bn 1,480.37 Bn - -2.30 Mn
7 Psyence Biomedical 241.78 Bn 241.78 Bn - 357,444.00
8 Vertex Pharmaceuticals 113.54 Bn 106.29 Bn 2.59 Bn 961.60 Mn
9 Abivax 94.26 Bn 94.26 Bn - -58.00 Mn
10 Prelude Therapeutics 314.40 Mn 169.80 Mn - 13.60 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 13.60 Mn
Dec 31, 2025 17.99 Mn
Sep 30, 2025 21.71 Mn
Jun 30, 2025 25.78 Mn
Mar 31, 2025 28.82 Mn
Dec 31, 2024 31.62 Mn
Sep 30, 2024 29.46 Mn
Jun 30, 2024 29.51 Mn
Mar 31, 2024 27.41 Mn
Dec 31, 2023 30.33 Mn
Sep 30, 2023 26.26 Mn
Jun 30, 2023 24.97 Mn
Mar 31, 2023 21.83 Mn
Dec 31, 2022 25.87 Mn
Sep 30, 2022 22.89 Mn
Jun 30, 2022 21.31 Mn
Mar 31, 2022 22.82 Mn
Dec 31, 2021 25.18 Mn
Sep 30, 2021 22.72 Mn
Jun 30, 2021 22.41 Mn