Prelude Therapeutics (PRLD) Research & Development (2019 - 2026)
Prelude Therapeutics' (PRLD) quarterly Research & Development came in at $13.6 million in Q1 2026, down 52.8% year-on-year from $28.8 million in Q1 2025, and down 24.41% quarter-over-quarter from $18.0 million in Q4 2025.
Prelude Therapeutics (PRLD) Research & Development (2019 - 2026) Analysis & Trends
Prelude Therapeutics has disclosed Research & Development across 8 years of filings, most recently posting $13.6 million for Q1 2026.
- Research & Development for Q1 2026 came in at $13.6 million, down 52.8% year-over-year; the trailing twelve-month figure through Mar 2026 was $79.1 million (down 33.77% YoY), and the FY2025 annual result was $94.3 million, down 20.08% from the prior year.
- Research & Development came in at $13.6 million for Q1 2026 at Prelude Therapeutics, down from $18.0 million in the prior quarter.
- In the past five years, Research & Development ranged from a high of $31.6 million in Q4 2024 to a low of $13.6 million in Q1 2026.
- The 5-year median for Research & Development is $25.8 million (2025), against an average of $24.8 million.
- Across the five-year window, Research & Development soared 38.56% in 2022 and plunged 52.8% in 2026, its largest moves.
- Prelude Therapeutics' Research & Development stood at $25.9 million in 2022, then advanced by 17.25% to $30.3 million in 2023, then increased by 4.25% to $31.6 million in 2024, then tumbled by 43.1% to $18.0 million in 2025, then slipped by 24.41% to $13.6 million in 2026.
- The last three Research & Development figures came in at $13.6 million (Q1 2026), $18.0 million (Q4 2025), and $21.7 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | R&D (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 723,416.35 Bn | 723,416.32 Bn | - | 4.32 Mn |
| 2 | Belite Bio | 57,340.00 Bn | 57,340.00 Bn | - | 15.66 Mn |
| 3 | Quantum Biopharma | 19,125.08 Bn | 19,125.08 Bn | - | 626,092.00 |
| 4 | Legend Biotech | 3,262.00 Bn | 3,261.71 Bn | 242.10 Mn | -101.30 Mn |
| 5 | Akari Therapeutics | 1,789.67 Bn | 1,789.67 Bn | - | 1.46 Mn |
| 6 | Evaxion A | 1,480.39 Bn | 1,480.37 Bn | - | -2.30 Mn |
| 7 | Psyence Biomedical | 241.78 Bn | 241.78 Bn | - | 357,444.00 |
| 8 | Vertex Pharmaceuticals | 113.54 Bn | 106.29 Bn | 2.59 Bn | 961.60 Mn |
| 9 | Abivax | 94.26 Bn | 94.26 Bn | - | -58.00 Mn |
| 10 | Prelude Therapeutics | 314.40 Mn | 169.80 Mn | - | 13.60 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | 13.60 Mn |
| Dec 31, 2025 | 17.99 Mn |
| Sep 30, 2025 | 21.71 Mn |
| Jun 30, 2025 | 25.78 Mn |
| Mar 31, 2025 | 28.82 Mn |
| Dec 31, 2024 | 31.62 Mn |
| Sep 30, 2024 | 29.46 Mn |
| Jun 30, 2024 | 29.51 Mn |
| Mar 31, 2024 | 27.41 Mn |
| Dec 31, 2023 | 30.33 Mn |
| Sep 30, 2023 | 26.26 Mn |
| Jun 30, 2023 | 24.97 Mn |
| Mar 31, 2023 | 21.83 Mn |
| Dec 31, 2022 | 25.87 Mn |
| Sep 30, 2022 | 22.89 Mn |
| Jun 30, 2022 | 21.31 Mn |
| Mar 31, 2022 | 22.82 Mn |
| Dec 31, 2021 | 25.18 Mn |
| Sep 30, 2021 | 22.72 Mn |
| Jun 30, 2021 | 22.41 Mn |