Prelude Therapeutics (PRLD) Net Margin (2024 - 2026)
Prelude Therapeutics' (PRLD) quarterly Net Margin came in at 309.54% in Q1 2026, down 0.63% quarter-over-quarter from 307.59% in Q4 2025.
Prelude Therapeutics (PRLD) Net Margin (2024 - 2026) Analysis & Trends
Prelude Therapeutics has disclosed Net Margin across 3 years of filings, most recently posting 309.54% for Q1 2026.
- Net Margin for Q1 2026 came in at 309.54%, changed N/A year-over-year; the trailing twelve-month figure through Mar 2026 was 503.21% (changed N/A YoY), and the FY2025 annual result was 861.33%, up 113458.0% from the prior year.
- Net Margin came in at 309.54% for Q1 2026 at Prelude Therapeutics, down from 307.59% in the prior quarter.
- In the past five years, Net Margin ranged from a high of 307.59% in Q4 2025 to a low of 1145.87% in Q3 2024.
- The 3-year median for Net Margin is 314.12% (2025), against an average of 584.58%.
- Peak annual rise in Net Margin reached 83174 bps in 2025, while the deepest fall reached 53819 bps in 2025.
- Prelude Therapeutics' Net Margin stood at 845.78% in 2024, then jumped by 64 bps to 307.59% in 2025, then decreased by 1 bps to 309.54% in 2026.
- The last three Net Margin figures came in at 309.54% (Q1 2026), 307.59% (Q4 2025), and 314.12% (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | - |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | - |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | 0.82% |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | - |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | - |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | - |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 34.53% |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | - |
| 10 | Prelude Therapeutics | 358.14 Mn | 213.54 Mn | - | -309.54% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -309.54% |
| Dec 31, 2025 | -307.59% |
| Sep 30, 2025 | -314.12% |
| Dec 31, 2024 | -845.78% |
| Sep 30, 2024 | -1,145.87% |