Prelude Therapeutics (PRLD) Net Margin (2024 - 2026)
Prelude Therapeutics (PRLD) posted Net Margin of 752.05% for Q1 2026, down 134.57% sequentially from 320.6% in Q4 2025.
Analysis
Prelude Therapeutics (PRLD) Net Margin (2024 - 2026) Analysis & Trends
Prelude Therapeutics has reported Net Margin for 3 years, with the latest figure at 752.05% in Q1 2026.
- Quarterly Net Margin changed N/A year-over-year to 752.05% in Q1 2026, while the trailing twelve-month figure through Mar 2026 was 891.23% (changed N/A YoY) and the FY2025 annual result came in at 2606.84%, up 199825.0% from the prior year.
- Net Margin fell to 752.05% in Q1 2026 per PRLD's latest filing, from 320.6% in the prior quarter.
- Over five years, Net Margin peaked at 320.6% in Q4 2025 and troughed at 2549.4% in Q3 2024.
- A 3-year average of 1025.52% and a median of 752.05% in 2026 frame the typical range for Net Margin.
- The widest YoY moves for Net Margin: up 190294 bps in 2025, down 53847 bps in 2025.
- Over 3 years, Net Margin stood at 859.08% in 2024, then surged by 63 bps to 320.6% in 2025, then tumbled by 135 bps to 752.05% in 2026.
- According to Business Quant data, Net Margin over the past three periods registered 752.05%, 320.6%, and 646.46% for Q1 2026, Q4 2025, and Q3 2025 respectively.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 138.92 Bn | 131.07 Bn | 2.84 Bn | 32.99% |
| 2 | Regeneron Pharmaceuticals | 85.55 Bn | 77.56 Bn | 3.93 Bn | 30.23% |
| 3 | Argenx Se | 63.55 Bn | 58.37 Bn | 1.37 Bn | 31.16% |
| 4 | Moderna | 58.26 Bn | 53.13 Bn | 52.00 Mn | -539.31% |
| 5 | Revolution Medicines | 44.08 Bn | 44.08 Bn | - | - |
| 6 | BeOne Medicines | 39.98 Bn | 34.89 Bn | 1.53 Bn | 13.90% |
| 7 | Alnylam Pharmaceuticals | 35.32 Bn | 32.01 Bn | 992.69 Mn | 12.74% |
| 8 | Royalty Pharma | 28.42 Bn | 27.59 Bn | - | 12.09% |
| 9 | Insmed | 27.41 Bn | 26.25 Bn | 358.27 Mn | -3.12% |
| 10 | Prelude Therapeutics | 539.17 Mn | 258.54 Mn | - | -270.93% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -270.93% |
| Mar 31, 2026 | -309.54% |
| Dec 31, 2025 | -307.59% |
| Sep 30, 2025 | -314.12% |
| Dec 31, 2024 | -845.78% |
| Sep 30, 2024 | -1,145.87% |