Prelude Therapeutics (PRLD) Free Cash Flow (2019 - 2026)

Prelude Therapeutics (PRLD) reported Free Cash Flow of -$21.7 million for Q1 2026, up 36.74% on a YoY basis from -$15.9 million in Q1 2025, and down 193.8% sequentially from $23.1 million in Q4 2025.

Prelude Therapeutics (PRLD) Free Cash Flow (2019 - 2026) Analysis & Trends

Prelude Therapeutics (PRLD) has 8 years of Free Cash Flow data on file, last reported at -$21.7 million in Q1 2026.

  • For the quarter ending Q1 2026, Free Cash Flow rose 36.74% year-over-year to -$21.7 million; the trailing twelve-month figure through Mar 2026 stood at -$43.8 million (up 58.35% YoY), and the FY2025 full-year result was -$56.4 million, up 45.22% from the prior year.
  • Free Cash Flow eased to -$21.7 million in Q1 2026, from $23.1 million in the prior quarter.
  • In the past five years, Free Cash Flow ranged from a high of $23.1 million in Q4 2025 to a low of -$34.3 million in Q1 2025.
  • A 5-year average of -$22.1 million and a median of -$23.4 million in 2024 frame the typical range for Free Cash Flow.
  • Across the five-year window, Free Cash Flow sank 44.53% in 2023 and soared 215.35% in 2025, its largest moves.
  • Tracing PRLD's Free Cash Flow over 5 years: stood at -$22.7 million in 2022, then decreased by 8.87% to -$24.7 million in 2023, then increased by 18.88% to -$20.0 million in 2024, then soared by 215.35% to $23.1 million in 2025, then slumped by 193.8% to -$21.7 million in 2026.
  • Business Quant data shows PRLD's Free Cash Flow at -$21.7 million in Q1 2026, $23.1 million in Q4 2025, and -$19.1 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Free Cash Flow (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -19.58 Mn
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 158.09 Mn
4 NuCana 279.75 Bn 279.75 Bn - -1.53 Mn
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 1.29 Bn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 848.30 Mn
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn -
9 Revolution Medicines 37.78 Bn 37.78 Bn - -354.95 Mn
10 Prelude Therapeutics 324.30 Mn 179.71 Mn - -21.69 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -21.69 Mn
Mar 31, 2026 -21.69 Mn
Dec 31, 2025 23.12 Mn
Dec 31, 2025 23.12 Mn
Sep 30, 2025 -19.12 Mn
Sep 30, 2025 -19.12 Mn
Jun 30, 2025 -26.10 Mn
Jun 30, 2025 -26.10 Mn
Mar 31, 2025 -34.28 Mn
Mar 31, 2025 -34.28 Mn
Dec 31, 2024 -20.04 Mn
Dec 31, 2024 -20.04 Mn
Sep 30, 2024 -27.36 Mn
Sep 30, 2024 -27.36 Mn
Jun 30, 2024 -23.42 Mn
Jun 30, 2024 -23.42 Mn
Mar 31, 2024 -32.08 Mn
Mar 31, 2024 -32.08 Mn
Dec 31, 2023 -24.71 Mn
Dec 31, 2023 -24.71 Mn