Prelude Therapeutics (PRLD) Free Cash Flow (2019 - 2026)

Prelude Therapeutics' (PRLD) quarterly Free Cash Flow came in at -$21.7 million in Q1 2026, up 36.74% year-on-year from -$15.9 million in Q1 2025, and down 193.8% quarter-over-quarter from $23.1 million in Q4 2025.

Prelude Therapeutics (PRLD) Free Cash Flow (2019 - 2026) Analysis & Trends

Prelude Therapeutics has disclosed Free Cash Flow across 8 years of filings, most recently posting -$21.7 million for Q1 2026.

  • Free Cash Flow for Q1 2026 came in at -$21.7 million, up 36.74% year-over-year; the trailing twelve-month figure through Mar 2026 was -$43.8 million (up 58.35% YoY), and the FY2025 annual result was -$56.4 million, up 45.22% from the prior year.
  • Free Cash Flow came in at -$21.7 million for Q1 2026 at Prelude Therapeutics, down from $23.1 million in the prior quarter.
  • In the past five years, Free Cash Flow ranged from a high of $23.1 million in Q4 2025 to a low of -$34.3 million in Q1 2025.
  • The 5-year median for Free Cash Flow is -$23.4 million (2024), against an average of -$22.1 million.
  • Across the five-year window, Free Cash Flow tumbled 44.53% in 2023 and soared 215.35% in 2025, its largest moves.
  • Prelude Therapeutics' Free Cash Flow stood at -$20.4 million in 2022, then decreased by 21.17% to -$24.7 million in 2023, then rose by 18.88% to -$20.0 million in 2024, then jumped by 215.35% to $23.1 million in 2025, then sank by 193.8% to -$21.7 million in 2026.
  • The last three Free Cash Flow figures came in at -$21.7 million (Q1 2026), $23.1 million (Q4 2025), and -$19.1 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Free Cash Flow (Qtr)
1 Alterity Therapeutics 723,416.35 Bn 723,416.32 Bn - -
2 Belite Bio 57,340.00 Bn 57,340.00 Bn - -
3 Quantum Biopharma 19,125.08 Bn 19,125.08 Bn - -1.67 Mn
4 Legend Biotech 3,262.00 Bn 3,261.71 Bn 242.10 Mn -12.20 Mn
5 Akari Therapeutics 1,789.67 Bn 1,789.67 Bn - -2.49 Mn
6 Evaxion A 1,480.39 Bn 1,480.37 Bn - -
7 Psyence Biomedical 241.78 Bn 241.78 Bn - -
8 Vertex Pharmaceuticals 113.54 Bn 106.29 Bn 2.59 Bn 1.29 Bn
9 Abivax 94.26 Bn 94.26 Bn - 63,220.27
10 Prelude Therapeutics 314.40 Mn 169.80 Mn - -21.69 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -21.69 Mn
Mar 31, 2026 -21.69 Mn
Dec 31, 2025 23.12 Mn
Dec 31, 2025 23.12 Mn
Sep 30, 2025 -19.12 Mn
Sep 30, 2025 -19.12 Mn
Jun 30, 2025 -26.10 Mn
Jun 30, 2025 -26.10 Mn
Mar 31, 2025 -34.28 Mn
Mar 31, 2025 -34.28 Mn
Dec 31, 2024 -20.04 Mn
Dec 31, 2024 -20.04 Mn
Sep 30, 2024 -27.36 Mn
Sep 30, 2024 -27.36 Mn
Jun 30, 2024 -23.42 Mn
Jun 30, 2024 -23.42 Mn
Mar 31, 2024 -32.08 Mn
Mar 31, 2024 -32.08 Mn
Dec 31, 2023 -24.71 Mn
Dec 31, 2023 -24.71 Mn