Prelude Therapeutics (PRLD) Enterprise Value (2019 - 2026)

Prelude Therapeutics' (PRLD) quarterly Enterprise Value came in at -$144.6 million in Q1 2026, down 40.23% year-on-year from -$241.9 million in Q1 2025, and down 40.1% quarter-over-quarter from -$103.2 million in Q4 2025.

Prelude Therapeutics (PRLD) Enterprise Value (2019 - 2026) Analysis & Trends

Prelude Therapeutics has disclosed Enterprise Value across 8 years of filings, most recently posting -$144.6 million for Q1 2026.

  • Enterprise Value for Q1 2026 came in at -$144.6 million, down 40.23% year-over-year; the trailing twelve-month figure through Mar 2026 was -$144.6 million (down 40.23% YoY), and the FY2025 annual result was -$103.2 million, up 25.02% from the prior year.
  • Enterprise Value came in at -$144.6 million for Q1 2026 at Prelude Therapeutics, down from -$103.2 million in the prior quarter.
  • In the past five years, Enterprise Value ranged from a high of -$58.2 million in Q3 2025 to a low of -$270.2 million in Q1 2022.
  • The 5-year median for Enterprise Value is -$183.9 million (2024), against an average of -$181.2 million.
  • Across the five-year window, Enterprise Value soared 63.09% in 2025 and plunged 40.23% in 2026, its largest moves.
  • Prelude Therapeutics' Enterprise Value stood at -$205.8 million in 2022, then retreated by 15.17% to -$237.0 million in 2023, then surged by 41.91% to -$137.7 million in 2024, then advanced by 25.02% to -$103.2 million in 2025, then slumped by 40.1% to -$144.6 million in 2026.
  • The last three Enterprise Value figures came in at -$144.6 million (Q1 2026), -$103.2 million (Q4 2025), and -$58.2 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Enterprise Value (Qtr)
1 Alterity Therapeutics 723,416.35 Bn 723,416.32 Bn - -32.30 Mn
2 Belite Bio 57,340.00 Bn 57,340.00 Bn - -
3 Quantum Biopharma 19,125.08 Bn 19,125.08 Bn - -4.14 Mn
4 Legend Biotech 3,262.00 Bn 3,261.71 Bn 242.10 Mn -286.70 Mn
5 Akari Therapeutics 1,789.67 Bn 1,789.67 Bn - -2.77 Mn
6 Evaxion A 1,480.39 Bn 1,480.37 Bn - -18.44 Mn
7 Psyence Biomedical 241.78 Bn 241.78 Bn - -7.20 Mn
8 Vertex Pharmaceuticals 113.54 Bn 106.29 Bn 2.59 Bn -7.25 Bn
9 Abivax 94.26 Bn 94.26 Bn - -584.73 Mn
10 Prelude Therapeutics 314.40 Mn 169.80 Mn - -144.60 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -144.60 Mn
Dec 31, 2025 -103.21 Mn
Sep 30, 2025 -58.19 Mn
Jun 30, 2025 -124.76 Mn
Mar 31, 2025 -103.12 Mn
Dec 31, 2024 -137.66 Mn
Sep 30, 2024 -157.67 Mn
Jun 30, 2024 -183.89 Mn
Mar 31, 2024 -205.97 Mn
Dec 31, 2023 -236.98 Mn
Sep 30, 2023 -234.55 Mn
Jun 30, 2023 -259.03 Mn
Mar 31, 2023 -176.30 Mn
Dec 31, 2022 -205.77 Mn
Sep 30, 2022 -228.09 Mn
Jun 30, 2022 -250.35 Mn
Mar 31, 2022 -270.23 Mn
Dec 31, 2021 -295.28 Mn
Sep 30, 2021 -320.87 Mn
Jun 30, 2021 -343.12 Mn