Prelude Therapeutics (PRLD) Enterprise Value (2019 - 2026)

Prelude Therapeutics (PRLD) reported Enterprise Value of -$144.6 million for Q1 2026, down 40.23% on a YoY basis from -$241.9 million in Q1 2025, and down 40.1% sequentially from -$103.2 million in Q4 2025.

Prelude Therapeutics (PRLD) Enterprise Value (2019 - 2026) Analysis & Trends

Prelude Therapeutics (PRLD) has 8 years of Enterprise Value data on file, last reported at -$144.6 million in Q1 2026.

  • For the quarter ending Q1 2026, Enterprise Value fell 40.23% year-over-year to -$144.6 million; the trailing twelve-month figure through Mar 2026 stood at -$144.6 million (down 40.23% YoY), and the FY2025 full-year result was -$103.2 million, up 25.02% from the prior year.
  • Enterprise Value slipped to -$144.6 million in Q1 2026, from -$103.2 million in the prior quarter.
  • In the past five years, Enterprise Value ranged from a high of -$55.0 million in Q3 2025 to a low of -$270.2 million in Q1 2022.
  • A 5-year average of -$181.0 million and a median of -$183.9 million in 2024 frame the typical range for Enterprise Value.
  • Across the five-year window, Enterprise Value jumped 65.14% in 2025 and slumped 40.23% in 2026, its largest moves.
  • Tracing PRLD's Enterprise Value over 5 years: stood at -$205.8 million in 2022, then fell by 15.17% to -$237.0 million in 2023, then jumped by 41.91% to -$137.7 million in 2024, then gained by 25.02% to -$103.2 million in 2025, then tumbled by 40.1% to -$144.6 million in 2026.
  • Business Quant data shows PRLD's Enterprise Value at -$144.6 million in Q1 2026, -$103.2 million in Q4 2025, and -$55.0 million in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Enterprise Value (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -283.54 Mn
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -61.40 Mn
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn -4.79 Bn
4 NuCana 279.75 Bn 279.75 Bn - -32.26 Mn
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn -7.25 Bn
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn -8.75 Bn
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn -5.18 Bn
9 Revolution Medicines 37.78 Bn 37.78 Bn - -1.91 Bn
10 Prelude Therapeutics 324.30 Mn 179.71 Mn - -144.60 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -144.60 Mn
Dec 31, 2025 -103.21 Mn
Sep 30, 2025 -54.96 Mn
Jun 30, 2025 -124.76 Mn
Mar 31, 2025 -103.12 Mn
Dec 31, 2024 -137.66 Mn
Sep 30, 2024 -157.67 Mn
Jun 30, 2024 -183.89 Mn
Mar 31, 2024 -205.97 Mn
Dec 31, 2023 -236.98 Mn
Sep 30, 2023 -234.55 Mn
Jun 30, 2023 -259.03 Mn
Mar 31, 2023 -176.30 Mn
Dec 31, 2022 -205.77 Mn
Sep 30, 2022 -228.09 Mn
Jun 30, 2022 -250.35 Mn
Mar 31, 2022 -270.23 Mn
Dec 31, 2021 -295.28 Mn
Sep 30, 2021 -320.87 Mn
Jun 30, 2021 -343.12 Mn