Prelude Therapeutics (PRLD) EBITDA Margin (2024 - 2026)
Prelude Therapeutics (PRLD) posted EBITDA Margin of 309.54% for Q1 2026, down 0.63% sequentially from 307.59% in Q4 2025.
Analysis
Prelude Therapeutics (PRLD) EBITDA Margin (2024 - 2026) Analysis & Trends
Prelude Therapeutics has reported EBITDA Margin for 3 years, with the latest figure at 309.54% in Q1 2026.
- Quarterly EBITDA Margin changed N/A year-over-year to 309.54% in Q1 2026, while the trailing twelve-month figure through Mar 2026 was 503.21% (changed N/A YoY) and the FY2025 annual result came in at 861.33%, up 113458.0% from the prior year.
- EBITDA Margin eased to 309.54% in Q1 2026 per PRLD's latest filing, from 307.59% in the prior quarter.
- Over five years, EBITDA Margin peaked at 307.59% in Q4 2025 and troughed at 1145.87% in Q3 2024.
- A 3-year average of 584.58% and a median of 314.12% in 2025 frame the typical range for EBITDA Margin.
- The widest YoY moves for EBITDA Margin: up 83174 bps in 2025, down 53819 bps in 2025.
- Over 3 years, EBITDA Margin stood at 845.78% in 2024, then soared by 64 bps to 307.59% in 2025, then dropped by 1 bps to 309.54% in 2026.
- According to Business Quant data, EBITDA Margin over the past three periods registered 309.54%, 307.59%, and 314.12% for Q1 2026, Q4 2025, and Q3 2025 respectively.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Vertex Pharmaceuticals | 138.47 Bn | 130.62 Bn | 2.84 Bn | 37.40% |
| 2 | Regeneron Pharmaceuticals | 85.18 Bn | 77.19 Bn | 3.93 Bn | 30.15% |
| 3 | Argenx Se | 63.38 Bn | 58.19 Bn | 1.37 Bn | 32.54% |
| 4 | Moderna | 58.09 Bn | 52.95 Bn | 52.00 Mn | -562.07% |
| 5 | Revolution Medicines | 44.33 Bn | 44.33 Bn | - | - |
| 6 | BeOne Medicines | 40.02 Bn | 34.92 Bn | 1.53 Bn | 19.06% |
| 7 | Alnylam Pharmaceuticals | 35.57 Bn | 32.27 Bn | 992.69 Mn | 17.93% |
| 8 | Royalty Pharma | 28.45 Bn | 27.61 Bn | - | 19.75% |
| 9 | Insmed | 27.48 Bn | 26.32 Bn | 358.27 Mn | -0.36% |
| 10 | Prelude Therapeutics | 539.17 Mn | 258.54 Mn | - | -270.93% |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -270.93% |
| Mar 31, 2026 | -309.54% |
| Dec 31, 2025 | -307.59% |
| Sep 30, 2025 | -314.12% |
| Dec 31, 2024 | -845.78% |
| Sep 30, 2024 | -1,145.87% |