Prelude Therapeutics PRLD
NASDAQ PRLD
$5.46 +0.21 (+4.00%)
As of: Sep 4, 2026 · 3:59 PM EDT

Prelude Therapeutics (PRLD) EBITDA Margin (2024 - 2026)

Prelude Therapeutics (PRLD) posted EBITDA Margin of 309.54% for Q1 2026, down 0.63% sequentially from 307.59% in Q4 2025.

Analysis

Prelude Therapeutics (PRLD) EBITDA Margin (2024 - 2026) Analysis & Trends

Prelude Therapeutics has reported EBITDA Margin for 3 years, with the latest figure at 309.54% in Q1 2026.

  • Quarterly EBITDA Margin changed N/A year-over-year to 309.54% in Q1 2026, while the trailing twelve-month figure through Mar 2026 was 503.21% (changed N/A YoY) and the FY2025 annual result came in at 861.33%, up 113458.0% from the prior year.
  • EBITDA Margin eased to 309.54% in Q1 2026 per PRLD's latest filing, from 307.59% in the prior quarter.
  • Over five years, EBITDA Margin peaked at 307.59% in Q4 2025 and troughed at 1145.87% in Q3 2024.
  • A 3-year average of 584.58% and a median of 314.12% in 2025 frame the typical range for EBITDA Margin.
  • The widest YoY moves for EBITDA Margin: up 83174 bps in 2025, down 53819 bps in 2025.
  • Over 3 years, EBITDA Margin stood at 845.78% in 2024, then soared by 64 bps to 307.59% in 2025, then dropped by 1 bps to 309.54% in 2026.
  • According to Business Quant data, EBITDA Margin over the past three periods registered 309.54%, 307.59%, and 314.12% for Q1 2026, Q4 2025, and Q3 2025 respectively.
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA Margin (Qtr)
1 Vertex Pharmaceuticals 138.47 Bn 130.62 Bn 2.84 Bn 37.40%
2 Regeneron Pharmaceuticals 85.18 Bn 77.19 Bn 3.93 Bn 30.15%
3 Argenx Se 63.38 Bn 58.19 Bn 1.37 Bn 32.54%
4 Moderna 58.09 Bn 52.95 Bn 52.00 Mn -562.07%
5 Revolution Medicines 44.33 Bn 44.33 Bn - -
6 BeOne Medicines 40.02 Bn 34.92 Bn 1.53 Bn 19.06%
7 Alnylam Pharmaceuticals 35.57 Bn 32.27 Bn 992.69 Mn 17.93%
8 Royalty Pharma 28.45 Bn 27.61 Bn - 19.75%
9 Insmed 27.48 Bn 26.32 Bn 358.27 Mn -0.36%
10 Prelude Therapeutics 539.17 Mn 258.54 Mn - -270.93%
Historic Data

Historic Data

Download Data
DateValue
Jun 30, 2026 -270.93%
Mar 31, 2026 -309.54%
Dec 31, 2025 -307.59%
Sep 30, 2025 -314.12%
Dec 31, 2024 -845.78%
Sep 30, 2024 -1,145.87%