Prelude Therapeutics (PRLD) Change in Cash (2019 - 2026)

Prelude Therapeutics (PRLD) posted Change in Cash of -$13.5 million for Q1 2026, down 9.97% sequentially from -$12.3 million in Q4 2025, and down 148.57% YoY from $27.8 million in Q1 2025.

Prelude Therapeutics (PRLD) Change in Cash (2019 - 2026) Analysis & Trends

Prelude Therapeutics has reported Change in Cash for 8 years, with the latest figure at -$13.5 million in Q1 2026.

  • Quarterly Change in Cash fell 148.57% year-over-year to -$13.5 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$19.3 million (down 224.16% YoY) and the FY2025 annual result came in at $22.0 million, up 271.44% from the prior year.
  • Change in Cash fell to -$13.5 million in Q1 2026 per PRLD's latest filing, from -$12.3 million in the prior quarter.
  • Over five years, Change in Cash peaked at $27.8 million in Q1 2025 and troughed at -$21.4 million in Q4 2022.
  • A 5-year average of -$640058.8 and a median of -$584000.0 in 2024 frame the typical range for Change in Cash.
  • The widest YoY moves for Change in Cash: up 4859.42% in 2025, down 1016.12% in 2025.
  • Over 5 years, Change in Cash stood at -$21.4 million in 2022, then soared by 143.87% to $9.4 million in 2023, then sank by 85.74% to $1.3 million in 2024, then tumbled by 1016.12% to -$12.3 million in 2025, then fell by 9.97% to -$13.5 million in 2026.
  • According to Business Quant data, Change in Cash over the past three periods registered -$13.5 million, -$12.3 million, and $21.0 million for Q1 2026, Q4 2025, and Q3 2025 respectively.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Change in Cash (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 649.20 Mn
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn -504.60 Mn
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn -
4 Revolution Medicines 43.64 Bn 43.64 Bn - 374.50 Mn
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 427.25 Mn
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn -1.97 Mn
7 Royalty Pharma 33.72 Bn 35.84 Bn - 225.59 Mn
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn -2.94 Mn
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn -37.42 Mn
10 Prelude Therapeutics 442.91 Mn 162.28 Mn - 4.74 Mn

Historic Data

Download Data
DateValue
Jun 30, 2026 4.74 Mn
Mar 31, 2026 -13.50 Mn
Dec 31, 2025 -12.28 Mn
Sep 30, 2025 20.97 Mn
Jun 30, 2025 -14.52 Mn
Mar 31, 2025 27.80 Mn
Dec 31, 2024 1.34 Mn
Sep 30, 2024 -16.69 Mn
Jun 30, 2024 3.12 Mn
Mar 31, 2024 -584,000.00
Dec 31, 2023 9.40 Mn
Sep 30, 2023 -10.55 Mn
Jun 30, 2023 8.25 Mn
Mar 31, 2023 -12.40 Mn
Dec 31, 2022 -21.42 Mn
Sep 30, 2022 1.32 Mn
Jun 30, 2022 -928,000.00
Mar 31, 2022 19.81 Mn
Dec 31, 2021 -25.55 Mn
Sep 30, 2021 -281.70 Mn