Prelude Therapeutics (PRLD) Change in Cash (2019 - 2026)

Prelude Therapeutics' (PRLD) quarterly Change in Cash came in at -$13.5 million in Q1 2026, down 148.57% year-on-year from $27.8 million in Q1 2025, and down 9.97% quarter-over-quarter from -$12.3 million in Q4 2025.

Prelude Therapeutics (PRLD) Change in Cash (2019 - 2026) Analysis & Trends

Prelude Therapeutics has disclosed Change in Cash across 8 years of filings, most recently posting -$13.5 million for Q1 2026.

  • Change in Cash for Q1 2026 came in at -$13.5 million, down 148.57% year-over-year; the trailing twelve-month figure through Mar 2026 was -$19.3 million (down 224.16% YoY), and the FY2025 annual result was $22.0 million, up 271.44% from the prior year.
  • Change in Cash came in at -$13.5 million for Q1 2026 at Prelude Therapeutics, down from -$12.3 million in the prior quarter.
  • In the past five years, Change in Cash ranged from a high of $27.8 million in Q1 2025 to a low of -$21.4 million in Q4 2022.
  • The 5-year median for Change in Cash is -$584000.0 (2024), against an average of -$640058.8.
  • Peak annual rise in Change in Cash reached 4859.42% in 2025, while the deepest fall reached 1016.12% in 2025.
  • Prelude Therapeutics' Change in Cash stood at -$21.4 million in 2022, then jumped by 143.87% to $9.4 million in 2023, then sank by 85.74% to $1.3 million in 2024, then tumbled by 1016.12% to -$12.3 million in 2025, then dropped by 9.97% to -$13.5 million in 2026.
  • The last three Change in Cash figures came in at -$13.5 million (Q1 2026), -$12.3 million (Q4 2025), and $21.0 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) Change in Cash (Qtr)
1 Alterity Therapeutics 723,416.35 Bn 723,416.32 Bn - -
2 Belite Bio 57,340.00 Bn 57,340.00 Bn - -
3 Quantum Biopharma 19,125.08 Bn 19,125.08 Bn - 2.44 Mn
4 Legend Biotech 3,262.00 Bn 3,261.71 Bn 242.10 Mn 623.00 Mn
5 Akari Therapeutics 1,789.67 Bn 1,789.67 Bn - -2.44 Mn
6 Evaxion A 1,480.39 Bn 1,480.37 Bn - -
7 Psyence Biomedical 241.78 Bn 241.78 Bn - -
8 Vertex Pharmaceuticals 113.54 Bn 106.29 Bn 2.59 Bn 417.10 Mn
9 Abivax 94.26 Bn 94.26 Bn - -45.97 Mn
10 Prelude Therapeutics 314.40 Mn 169.80 Mn - -13.50 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -13.50 Mn
Dec 31, 2025 -12.28 Mn
Sep 30, 2025 20.97 Mn
Jun 30, 2025 -14.52 Mn
Mar 31, 2025 27.80 Mn
Dec 31, 2024 1.34 Mn
Sep 30, 2024 -16.69 Mn
Jun 30, 2024 3.12 Mn
Mar 31, 2024 -584,000.00
Dec 31, 2023 9.40 Mn
Sep 30, 2023 -10.55 Mn
Jun 30, 2023 8.25 Mn
Mar 31, 2023 -12.40 Mn
Dec 31, 2022 -21.42 Mn
Sep 30, 2022 1.32 Mn
Jun 30, 2022 -928,000.00
Mar 31, 2022 19.81 Mn
Dec 31, 2021 -25.55 Mn
Sep 30, 2021 -281.70 Mn
Jun 30, 2021 -19.87 Mn