Praxis Precision Medicines PRAX
NASDAQ PRAX
$256.47 -8.02 (-3.03%)
At close: Oct 21, 2026 · 4:00 PM EDT

Praxis Precision Medicines (PRAX) Return on Equity [ROE] (2020 - 2026)

Updated

Praxis Precision Medicines (PRAX) reported Return on Equity [ROE] of -27.49% for Q2 2026, up 36.91 percentage points from -64.40% a year earlier and up 3.74 percentage points from the prior quarter.

Analysis

Praxis Precision Medicines (PRAX) Return on Equity [ROE] (2020 - 2026) Analysis & Trends

For FY2025, Praxis Precision Medicines posted Return on Equity [ROE] of -49.29%, up 28.43 percentage points from FY2024.

  • Return on Equity [ROE] has a five-year change of +10.60 percentage points (FY2020 to FY2025).
  • By year, Return on Equity [ROE] came in at -77.72% in FY2024 (+95.66 pp), -173.38% in FY2023 (-42.44 pp), -130.94% in FY2022 (-68.86 pp) and -62.07% in FY2021 (-2.18 pp).
  • The Q2 2026 figure ranks as the highest quarterly Return on Equity [ROE] in data going back to Q4 2020.
  • Year over year, Return on Equity [ROE] gained in five of the last eight quarters, with an average year-over-year change of +30.56 percentage points.
  • The high point for year-over-year Return on Equity [ROE] in five years was Q1 2024 (a gain of 174.65 percentage points); the low point was Q4 2022 (a drop of 175.71 percentage points).
  • Per Business Quant data, the three quarters before Q2 2026 came in at -31.23% (Q1 2026), -53.40% (Q4 2025) and -78.40% (Q3 2025).
Peer Set

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROE (Qtr)
1 Eli Lilly 1,136.97 Bn 1,105.55 Bn 19.71 Bn 82.09%
2 Johnson & Johnson 619.72 Bn 538.25 Bn 17.26 Bn 25.32%
3 AbbVie 503.40 Bn 476.52 Bn 12.70 Bn -
4 Merck 370.15 Bn 324.53 Bn 12.21 Bn 7.21%
5 Novartis Ag 298.64 Bn 262.63 Bn 11.24 Bn 31.52%
6 Astrazeneca 261.07 Bn 234.76 Bn 12.86 Bn 21.39%
7 Amgen 237.00 Bn 192.40 Bn 7.24 Bn 83.75%
8 Gilead Sciences 191.24 Bn 165.43 Bn 6.22 Bn -18.38%
9 Pfizer 170.31 Bn 116.96 Bn 10.94 Bn 4.97%
10 Praxis Precision Medicines 7.47 Bn 5.06 Bn - -27.49%
Historic Data

Historic Data

Download Data
DateValue
Jun 30, 2026 -27.49%
Mar 31, 2026 -31.23%
Dec 31, 2025 -53.40%
Sep 30, 2025 -78.40%
Jun 30, 2025 -64.40%
Mar 31, 2025 -52.68%
Dec 31, 2024 -48.34%
Sep 30, 2024 -40.91%
Jun 30, 2024 -40.91%
Mar 31, 2024 -86.97%
Dec 31, 2023 -161.58%
Sep 30, 2023 -145.57%
Jun 30, 2023 -186.31%
Mar 31, 2023 -261.62%
Dec 31, 2022 -236.82%
Sep 30, 2022 -189.95%
Jun 30, 2022 -140.97%
Mar 31, 2022 -94.40%
Dec 31, 2021 -61.11%
Sep 30, 2021 -42.62%
API Access

Praxis Precision Medicines Return on Equity [ROE] API

Pull this series into your own models, spreadsheets and apps with the Business Quant Historical Metrics API. The request below matches the chart above — change the frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.

https://data.businessquant.com/historic?slug=return-on-equity-%5Broe%5D&ticker=PRAX&period=max&api_key=YOUR_API_KEY