Praxis Precision Medicines (PRAX) Operating Income (2019 - 2026)
Praxis Precision Medicines (PRAX) posted Operating Income of -$96.9 million for Q2 2026, up 8.46% on a QoQ basis from -$105.9 million in Q1 2026, and down 27.39% year-over-year from -$133.5 million in Q2 2025.
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Praxis Precision Medicines (PRAX) Operating Income (2019 - 2026) Analysis & Trends
Praxis Precision Medicines has reported Operating Income for 8 years, with the latest figure at -$96.9 million in Q2 2026.
- On a quarterly basis, Operating Income fell 27.39% year-over-year to -$96.9 million in Q2 2026; TTM through Jun 2026 was -$378.2 million, a 39.24% decrease from a year earlier, with the FY2025 full-year figure at -$326.2 million, down 62.96% from the prior year.
- Operating Income was -$96.9 million for Q2 2026 at Praxis Precision Medicines, up from -$105.9 million in the prior quarter.
- The five-year high for Operating Income was -$25.5 million in Q3 2023, with the low at -$105.9 million in Q1 2026.
- Average Operating Income over 5 years is -$59.5 million, with a median of -$58.6 million recorded in 2022.
- The sharpest annual moves came in 2022 and 2023: Operating Income plunged 151.1% in 2022, then jumped 44.67% in 2023.
- Over 5 years, Operating Income stood at -$41.5 million in 2022, then jumped by 32.92% to -$27.8 million in 2023, then slumped by 130.01% to -$64.0 million in 2024, then tumbled by 51.74% to -$97.0 million in 2025, then rose by 0.14% to -$96.9 million in 2026.
- The last three Operating Income figures came in at -$96.9 million (Q2 2026), -$105.9 million (Q1 2026), and -$97.0 million (Q4 2025), per Business Quant data.
Peer Set
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Op. Inc (Qtr) |
|---|---|---|---|---|---|
| 1 | Amgen | 212.54 Bn | 198.55 Bn | 7.24 Bn | 3.51 Bn |
| 2 | Gilead Sciences | 186.84 Bn | 183.58 Bn | 6.22 Bn | -10.39 Bn |
| 3 | Vertex Pharmaceuticals | 129.39 Bn | 121.54 Bn | 2.84 Bn | 1.25 Bn |
| 4 | Regeneron Pharmaceuticals | 82.05 Bn | 74.06 Bn | 3.93 Bn | 1.29 Bn |
| 5 | Moderna | 69.00 Bn | 63.87 Bn | 52.00 Mn | -815.00 Mn |
| 6 | Argenx Se | 61.15 Bn | 55.97 Bn | 1.37 Bn | 493.00 Mn |
| 7 | Alnylam Pharmaceuticals | 32.67 Bn | 29.37 Bn | 992.69 Mn | 231.44 Mn |
| 8 | Biogen | 32.37 Bn | 31.08 Bn | 1.96 Bn | -644.50 Mn |
| 9 | Roivant Sciences | 28.18 Bn | 28.87 Bn | 1.16 Mn | -365.99 Mn |
| 10 | Praxis Precision Medicines | 8.34 Bn | 7.58 Bn | - | -96.90 Mn |
Historic Data
Download Data
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | -96.90 Mn |
| Mar 31, 2026 | -105.86 Mn |
| Dec 31, 2025 | -97.04 Mn |
| Sep 30, 2025 | -78.36 Mn |
| Jun 30, 2025 | -76.07 Mn |
| Mar 31, 2025 | -74.73 Mn |
| Dec 31, 2024 | -63.96 Mn |
| Sep 30, 2024 | -56.84 Mn |
| Jun 30, 2024 | -37.49 Mn |
| Mar 31, 2024 | -41.89 Mn |
| Dec 31, 2023 | -27.81 Mn |
| Sep 30, 2023 | -25.52 Mn |
| Jun 30, 2023 | -34.96 Mn |
| Mar 31, 2023 | -38.09 Mn |
| Dec 31, 2022 | -41.45 Mn |
| Sep 30, 2022 | -44.29 Mn |
| Jun 30, 2022 | -60.39 Mn |
| Mar 31, 2022 | -68.85 Mn |
| Dec 31, 2021 | -58.66 Mn |
| Sep 30, 2021 | -44.77 Mn |
API Access
Praxis Precision Medicines Operating Income API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=operating-income&ticker=PRAX&period=max&api_key=YOUR_API_KEYimport requests
url = "https://data.businessquant.com/historic"
params = {"slug": "operating-income", "ticker": "PRAX", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()const res = await fetch("https://data.businessquant.com/historic?slug=operating-income&ticker=PRAX&period=max&api_key=YOUR_API_KEY");
const data = await res.json();