Praxis Precision Medicines (PRAX) EBT (2019 - 2026)

Praxis Precision Medicines' (PRAX) quarterly EBT came in at -$562.1 million in Q1 2026, down 641.16% year-on-year from $103.9 million in Q1 2025, and down 39.25% quarter-over-quarter from -$403.6 million in Q4 2025.

Praxis Precision Medicines (PRAX) EBT (2019 - 2026) Analysis & Trends

Praxis Precision Medicines' EBT history runs 8 years deep, the most recent figure standing at -$562.1 million for Q1 2026.

  • On a quarterly basis, EBT fell 641.16% year-over-year to -$562.1 million in Q1 2026; TTM through Mar 2026 was -$1.1 billion, a 142.84% decrease from a year earlier, with the FY2025 full-year figure at -$736.1 million, down 75.91% from the prior year.
  • EBT slipped to -$562.1 million in Q1 2026 per PRAX's latest filing, from -$403.6 million in the prior quarter.
  • Across five years, EBT topped out at -$25.7 million in Q3 2023 and bottomed at -$562.1 million in Q1 2026.
  • The 5-year median for EBT is -$75.8 million (2025), against an average of -$137.2 million.
  • Across the five-year window, EBT surged 54.43% in 2023 and plunged 641.16% in 2026, its largest moves.
  • Year by year, EBT stood at -$184.1 million in 2022, then retreated by 13.17% to -$208.3 million in 2023, then sank by 35.5% to -$282.3 million in 2024, then slumped by 43.01% to -$403.6 million in 2025, then slumped by 39.25% to -$562.1 million in 2026.
  • Per Business Quant, the three latest PRAX EBT figures stand at -$562.1 million (Q1 2026), -$403.6 million (Q4 2025), and -$87.0 million (Q3 2025).

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBT (Qtr)
1 Oculis Holding AG 67,072.09 Bn 67,072.09 Bn - -36.97 Mn
2 Nanobiotix 1,894.61 Bn 1,894.55 Bn - -
3 Akari Therapeutics 1,014.18 Bn 1,014.18 Bn - -15.31 Mn
4 BeOne Medicines 471.64 Bn 466.85 Bn 1.35 Bn 259.22 Mn
5 Vertex Pharmaceuticals 121.72 Bn 114.47 Bn 2.59 Bn 1.25 Bn
6 Regeneron Pharmaceuticals 68.28 Bn 59.52 Bn 3.31 Bn 831.20 Mn
7 Belite Bio 61.40 Bn 61.40 Bn - -26.94 Mn
8 Argenx Se 56.94 Bn 56.94 Bn 1.18 Bn 438.00 Mn
9 Revolution Medicines 37.37 Bn 37.37 Bn - -453.82 Mn
10 Praxis Precision Medicines 9.37 Bn 8.58 Bn - -562.09 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -562.09 Mn
Dec 31, 2025 -403.64 Mn
Sep 30, 2025 -87.02 Mn
Jun 30, 2025 -77.90 Mn
Mar 31, 2025 -75.84 Mn
Dec 31, 2024 -282.26 Mn
Sep 30, 2024 -68.23 Mn
Jun 30, 2024 -39.27 Mn
Mar 31, 2024 -56.08 Mn
Dec 31, 2023 -208.31 Mn
Sep 30, 2023 -25.74 Mn
Jun 30, 2023 -35.01 Mn
Mar 31, 2023 -37.96 Mn
Dec 31, 2022 -184.07 Mn
Sep 30, 2022 -43.95 Mn
Jun 30, 2022 -61.22 Mn
Mar 31, 2022 -83.31 Mn
Dec 31, 2021 -58.59 Mn
Sep 30, 2021 -44.70 Mn
Jun 30, 2021 -36.40 Mn