Growth Metrics

Praxis Precision Medicines (PRAX) EBITDA (2022 - 2025)

Praxis Precision Medicines has reported EBITDA over the past 4 years, most recently at -$97.0 million for Q4 2025.

  • Quarterly results put EBITDA at -$97.0 million for Q4 2025, down 51.74% from a year ago — trailing twelve months through Dec 2025 was -$326.2 million (down 62.96% YoY), and the annual figure for FY2025 was -$326.2 million, down 62.96%.
  • EBITDA for Q4 2025 was -$97.0 million at Praxis Precision Medicines, down from -$78.4 million in the prior quarter.
  • Over the last five years, EBITDA for PRAX hit a ceiling of -$25.5 million in Q3 2023 and a floor of -$97.0 million in Q4 2025.
  • Median EBITDA over the past 4 years was -$50.6 million (2022), compared with a mean of -$54.2 million.
  • Biggest five-year swings in EBITDA: surged 44.67% in 2023 and later crashed 130.01% in 2024.
  • Praxis Precision Medicines' EBITDA stood at -$41.5 million in 2022, then skyrocketed by 32.92% to -$27.8 million in 2023, then crashed by 130.01% to -$64.0 million in 2024, then tumbled by 51.74% to -$97.0 million in 2025.
  • The last three reported values for EBITDA were -$97.0 million (Q4 2025), -$78.4 million (Q3 2025), and -$76.1 million (Q2 2025) per Business Quant data.