Growth Metrics

Praxis Precision Medicines (PRAX) EBITDA (2019 - 2026)

Praxis Precision Medicines' quarterly EBITDA came in at -$94.7 million in Q1 2026, down 36.7% year-on-year from -$149.6 million in Q1 2025, and up 2.4% quarter-over-quarter from -$97.0 million in Q4 2025.

Praxis Precision Medicines has reported EBITDA for 8 years, with the latest figure at -$94.7 million in Q1 2026.

  • For the quarter ending Q1 2026, EBITDA fell 36.7% year-over-year to -$94.7 million; the trailing twelve-month figure through Mar 2026 stood at -$346.2 million (down 52.12% YoY), and the FY2025 full-year result was -$326.2 million, down 62.96% from the prior year.
  • EBITDA for Q1 2026 stood at -$94.7 million, up from -$97.0 million in the prior quarter.
  • The five-year high for EBITDA was -$25.5 million in Q3 2023, with the low at -$97.0 million in Q4 2025.
  • Average EBITDA over 5 years is -$56.3 million, with a median of -$56.8 million recorded in 2024.
  • Year-over-year, EBITDA tumbled 151.82% in 2022 and soared 44.91% in 2023.
  • Tracing PRAX's EBITDA over 5 years: stood at -$41.5 million in 2022, then jumped by 32.92% to -$27.8 million in 2023, then slumped by 130.01% to -$64.0 million in 2024, then tumbled by 51.74% to -$97.0 million in 2025, then advanced by 2.4% to -$94.7 million in 2026.
  • The last three EBITDA figures came in at -$94.7 million (Q1 2026), -$97.0 million (Q4 2025), and -$78.4 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Quantum Biopharma 1,216,509.61 Bn 1,216,509.61 Bn - -13.63 Mn
2 Alterity Therapeutics 764,224.41 Bn 764,224.38 Bn - -
3 Legend Biotech 2,716.00 Bn 2,715.71 Bn 242.10 Mn -19.70 Mn
4 Nanobiotix 2,248.83 Bn 2,248.77 Bn - -
5 Akari Therapeutics 1,951.18 Bn 1,951.17 Bn - -14.44 Mn
6 Vertex Pharmaceuticals 113.69 Bn 106.44 Bn 2.59 Bn 1.14 Bn
7 Evaxion A 64.16 Bn 64.14 Bn - -3.82 Mn
8 Regeneron Pharmaceuticals 63.94 Bn 55.18 Bn 3.31 Bn 661.60 Mn
9 Alnylam Pharmaceuticals 40.13 Bn 37.12 Bn 959.66 Mn 201.19 Mn
10 Praxis Precision Medicines 10.11 Bn 9.32 Bn - -94.72 Mn

Historic Data

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DateValue
Mar 31, 2026 -94.72 Mn
Dec 31, 2025 -97.04 Mn
Sep 30, 2025 -78.36 Mn
Jun 30, 2025 -76.07 Mn
Mar 31, 2025 -69.29 Mn
Dec 31, 2024 -63.96 Mn
Sep 30, 2024 -56.84 Mn
Jun 30, 2024 -37.49 Mn
Mar 31, 2024 -41.89 Mn
Dec 31, 2023 -27.81 Mn
Sep 30, 2023 -25.52 Mn
Jun 30, 2023 -34.96 Mn
Mar 31, 2023 -38.09 Mn
Dec 31, 2022 -41.45 Mn
Sep 30, 2022 -44.29 Mn
Jun 30, 2022 -60.27 Mn
Mar 31, 2022 -69.15 Mn
Dec 31, 2021 -58.66 Mn
Sep 30, 2021 -44.77 Mn
Jun 30, 2021 -36.37 Mn
Mar 31, 2021 -27.46 Mn
Dec 31, 2020 -25.71 Mn
Sep 30, 2020 -16.22 Mn
Jun 30, 2020 -11.57 Mn
Mar 31, 2020 -8.47 Mn
Dec 31, 2019 -7.49 Mn
Sep 30, 2019 -10.65 Mn