Praxis Precision Medicines (PRAX) EBITDA (2019 - 2026)

Praxis Precision Medicines (PRAX) recorded quarterly EBITDA of -$94.7 million in Q1 2026, up 2.4% quarter-over-quarter from -$97.0 million in Q4 2025, and down 36.7% on a YoY basis from -$149.6 million in Q1 2025.

Praxis Precision Medicines (PRAX) EBITDA (2019 - 2026) Analysis & Trends

Praxis Precision Medicines' EBITDA history runs 8 years deep, the most recent figure standing at -$94.7 million for Q1 2026.

  • In Q1 2026, EBITDA fell 36.7% year-over-year to -$94.7 million; the TTM figure through Mar 2026 stood at -$346.2 million (down 52.12% YoY), while the FY2025 annual figure was -$326.2 million, down 62.96% from the prior year.
  • EBITDA was -$94.7 million for Q1 2026 at Praxis Precision Medicines, up from -$97.0 million in the prior quarter.
  • In the past five years, EBITDA ranged from a high of -$25.5 million in Q3 2023 to a low of -$97.0 million in Q4 2025.
  • Historically, EBITDA has averaged -$56.3 million across 5 years, with a median of -$56.8 million in 2024.
  • The sharpest annual moves came in 2022 and 2023: EBITDA tumbled 151.82% in 2022, then jumped 44.91% in 2023.
  • A 5-year view of EBITDA shows it stood at -$41.5 million in 2022, then soared by 32.92% to -$27.8 million in 2023, then tumbled by 130.01% to -$64.0 million in 2024, then plunged by 51.74% to -$97.0 million in 2025, then gained by 2.4% to -$94.7 million in 2026.
  • The last three EBITDA figures came in at -$94.7 million (Q1 2026), -$97.0 million (Q4 2025), and -$78.4 million (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBITDA (Qtr)
1 Alterity Therapeutics 925,601.88 Bn 925,601.85 Bn - -
2 Belite Bio 58,560.00 Bn 58,560.00 Bn - -26.92 Mn
3 Quantum Biopharma 17,284.41 Bn 17,284.40 Bn - -13.63 Mn
4 Legend Biotech 2,809.00 Bn 2,808.71 Bn 242.10 Mn -19.70 Mn
5 Evaxion A 1,334.43 Bn 1,334.42 Bn - -3.82 Mn
6 Akari Therapeutics 1,312.27 Bn 1,312.26 Bn - -14.44 Mn
7 Psyence Biomedical 212.16 Bn 212.16 Bn - -752,618.00
8 Vertex Pharmaceuticals 114.83 Bn 107.58 Bn 2.59 Bn 1.14 Bn
9 Abivax 91.96 Bn 91.96 Bn - -65.83 Mn
10 Praxis Precision Medicines 200.22 Mn -586.65 Mn - -94.72 Mn

Historic Data

Download Data
DateValue
Mar 31, 2026 -94.72 Mn
Dec 31, 2025 -97.04 Mn
Sep 30, 2025 -78.36 Mn
Jun 30, 2025 -76.07 Mn
Mar 31, 2025 -69.29 Mn
Dec 31, 2024 -63.96 Mn
Sep 30, 2024 -56.84 Mn
Jun 30, 2024 -37.49 Mn
Mar 31, 2024 -41.89 Mn
Dec 31, 2023 -27.81 Mn
Sep 30, 2023 -25.52 Mn
Jun 30, 2023 -34.96 Mn
Mar 31, 2023 -38.09 Mn
Dec 31, 2022 -41.45 Mn
Sep 30, 2022 -44.29 Mn
Jun 30, 2022 -60.27 Mn
Mar 31, 2022 -69.15 Mn
Dec 31, 2021 -58.66 Mn
Sep 30, 2021 -44.77 Mn
Jun 30, 2021 -36.37 Mn