Praxis Precision Medicines (PRAX) EBITDA (2019 - 2026)
Praxis Precision Medicines (PRAX) recorded quarterly EBITDA of -$94.7 million in Q1 2026, up 2.4% quarter-over-quarter from -$97.0 million in Q4 2025, and down 36.7% on a YoY basis from -$149.6 million in Q1 2025.
Praxis Precision Medicines (PRAX) EBITDA (2019 - 2026) Analysis & Trends
Praxis Precision Medicines' EBITDA history runs 8 years deep, the most recent figure standing at -$94.7 million for Q1 2026.
- In Q1 2026, EBITDA fell 36.7% year-over-year to -$94.7 million; the TTM figure through Mar 2026 stood at -$346.2 million (down 52.12% YoY), while the FY2025 annual figure was -$326.2 million, down 62.96% from the prior year.
- EBITDA was -$94.7 million for Q1 2026 at Praxis Precision Medicines, up from -$97.0 million in the prior quarter.
- In the past five years, EBITDA ranged from a high of -$25.5 million in Q3 2023 to a low of -$97.0 million in Q4 2025.
- Historically, EBITDA has averaged -$56.3 million across 5 years, with a median of -$56.8 million in 2024.
- The sharpest annual moves came in 2022 and 2023: EBITDA tumbled 151.82% in 2022, then jumped 44.91% in 2023.
- A 5-year view of EBITDA shows it stood at -$41.5 million in 2022, then soared by 32.92% to -$27.8 million in 2023, then tumbled by 130.01% to -$64.0 million in 2024, then plunged by 51.74% to -$97.0 million in 2025, then gained by 2.4% to -$94.7 million in 2026.
- The last three EBITDA figures came in at -$94.7 million (Q1 2026), -$97.0 million (Q4 2025), and -$78.4 million (Q3 2025), per Business Quant data.
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | EBITDA (Qtr) |
|---|---|---|---|---|---|
| 1 | Alterity Therapeutics | 925,601.88 Bn | 925,601.85 Bn | - | - |
| 2 | Belite Bio | 58,560.00 Bn | 58,560.00 Bn | - | -26.92 Mn |
| 3 | Quantum Biopharma | 17,284.41 Bn | 17,284.40 Bn | - | -13.63 Mn |
| 4 | Legend Biotech | 2,809.00 Bn | 2,808.71 Bn | 242.10 Mn | -19.70 Mn |
| 5 | Evaxion A | 1,334.43 Bn | 1,334.42 Bn | - | -3.82 Mn |
| 6 | Akari Therapeutics | 1,312.27 Bn | 1,312.26 Bn | - | -14.44 Mn |
| 7 | Psyence Biomedical | 212.16 Bn | 212.16 Bn | - | -752,618.00 |
| 8 | Vertex Pharmaceuticals | 114.83 Bn | 107.58 Bn | 2.59 Bn | 1.14 Bn |
| 9 | Abivax | 91.96 Bn | 91.96 Bn | - | -65.83 Mn |
| 10 | Praxis Precision Medicines | 200.22 Mn | -586.65 Mn | - | -94.72 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -94.72 Mn |
| Dec 31, 2025 | -97.04 Mn |
| Sep 30, 2025 | -78.36 Mn |
| Jun 30, 2025 | -76.07 Mn |
| Mar 31, 2025 | -69.29 Mn |
| Dec 31, 2024 | -63.96 Mn |
| Sep 30, 2024 | -56.84 Mn |
| Jun 30, 2024 | -37.49 Mn |
| Mar 31, 2024 | -41.89 Mn |
| Dec 31, 2023 | -27.81 Mn |
| Sep 30, 2023 | -25.52 Mn |
| Jun 30, 2023 | -34.96 Mn |
| Mar 31, 2023 | -38.09 Mn |
| Dec 31, 2022 | -41.45 Mn |
| Sep 30, 2022 | -44.29 Mn |
| Jun 30, 2022 | -60.27 Mn |
| Mar 31, 2022 | -69.15 Mn |
| Dec 31, 2021 | -58.66 Mn |
| Sep 30, 2021 | -44.77 Mn |
| Jun 30, 2021 | -36.37 Mn |