Puma Biotechnology (PBYI) Net Margin (2017 - 2026)
Puma Biotechnology (PBYI) posted Net Margin of 8.37% for Q1 2026, down 137.47% on a QoQ basis from 22.35% in Q4 2025, and down 1484.0% year-over-year from 0.61% in Q1 2025.
Puma Biotechnology (PBYI) Net Margin (2017 - 2026) Analysis & Trends
Puma Biotechnology's Net Margin history runs 10 years deep, the most recent figure standing at 8.37% for Q1 2026.
- Quarterly Net Margin fell 1484.0% year-over-year to 8.37% in Q1 2026, while the trailing twelve-month figure through Mar 2026 was 12.24% (up 897.0% YoY) and the FY2025 annual result came in at 15.12%, up 1520.0% from the prior year.
- Net Margin was 8.37% for Q1 2026 at Puma Biotechnology, down from 22.35% in the prior quarter.
- Across five years, Net Margin topped out at 25.23% in Q3 2024 and bottomed at 18.87% in Q4 2024.
- A 5-year average of 4.09% and a median of 3.9% in 2023 frame the typical range for Net Margin.
- Annual changes were most pronounced in 2022 — Net Margin surged 9597 bps — and 2024, when it sank 3611 bps.
- Puma Biotechnology's Net Margin stood at 5.88% in 2022, then surged by 393 bps to 17.24% in 2023, then plunged by 209 bps to 18.87% in 2024, then surged by 218 bps to 22.35% in 2025, then plunged by 137 bps to 8.37% in 2026.
- Business Quant data shows PBYI's Net Margin at 8.37% in Q1 2026, 22.35% in Q4 2025, and 16.23% in Q3 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Net Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 68,785.72 Bn | 68,785.72 Bn | - | - |
| 2 | Nanobiotix | 1,895.57 Bn | 1,895.51 Bn | - | - |
| 3 | BeOne Medicines | 471.35 Bn | 466.56 Bn | 1.35 Bn | 15.02% |
| 4 | NuCana | 279.75 Bn | 279.75 Bn | - | - |
| 5 | Vertex Pharmaceuticals | 120.24 Bn | 113.00 Bn | 2.59 Bn | 34.53% |
| 6 | Regeneron Pharmaceuticals | 67.80 Bn | 59.04 Bn | 3.31 Bn | 20.17% |
| 7 | Belite Bio | 62.51 Bn | 62.51 Bn | - | - |
| 8 | Argenx Se | 57.38 Bn | 57.38 Bn | 1.41 Bn | 30.33% |
| 9 | Revolution Medicines | 37.78 Bn | 37.78 Bn | - | - |
| 10 | Puma Biotechnology | 407.27 Mn | 368.99 Mn | 34.39 Mn | -8.37% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -8.37% |
| Dec 31, 2025 | 22.35% |
| Sep 30, 2025 | 16.23% |
| Jun 30, 2025 | 11.17% |
| Mar 31, 2025 | 6.46% |
| Dec 31, 2024 | -18.87% |
| Sep 30, 2024 | 25.23% |
| Jun 30, 2024 | -9.62% |
| Mar 31, 2024 | -11.00% |
| Dec 31, 2023 | 17.24% |
| Sep 30, 2023 | 10.33% |
| Jun 30, 2023 | 3.90% |
| Mar 31, 2023 | 2.65% |
| Dec 31, 2022 | -5.88% |
| Sep 30, 2022 | -0.63% |
| Jun 30, 2022 | 15.74% |
| Mar 31, 2022 | -7.44% |
| Dec 31, 2021 | 7.63% |
| Sep 30, 2021 | -96.60% |
| Jun 30, 2021 | -9.56% |