Puma Biotechnology (PBYI) Enterprise Value (2011 - 2026)
Puma Biotechnology (PBYI) posted Enterprise Value of -$38.3 million for Q1 2026, down 20.67% on a QoQ basis from -$31.7 million in Q4 2025, and up 58.91% year-over-year from -$24.1 million in Q1 2025.
Puma Biotechnology (PBYI) Enterprise Value (2011 - 2026) Analysis & Trends
Puma Biotechnology's Enterprise Value history runs 16 years deep, the most recent figure standing at -$38.3 million for Q1 2026.
- Quarterly Enterprise Value rose 58.91% year-over-year to -$38.3 million in Q1 2026, while the trailing twelve-month figure through Mar 2026 was -$38.3 million (up 58.91% YoY) and the FY2025 annual result came in at -$31.7 million, up 68.58% from the prior year.
- Enterprise Value was -$38.3 million for Q1 2026 at Puma Biotechnology, down from -$31.7 million in the prior quarter.
- Across five years, Enterprise Value topped out at -$31.7 million in Q4 2025 and bottomed at -$107.2 million in Q1 2024.
- A 5-year average of -$78.0 million and a median of -$81.1 million in 2022 frame the typical range for Enterprise Value.
- Annual changes were most pronounced in 2024 — Enterprise Value sank 50.47% — and 2025, when it soared 68.58%.
- Puma Biotechnology's Enterprise Value stood at -$81.1 million in 2022, then slipped by 18.34% to -$95.9 million in 2023, then decreased by 5.24% to -$101.0 million in 2024, then surged by 68.58% to -$31.7 million in 2025, then dropped by 20.67% to -$38.3 million in 2026.
- Business Quant data shows PBYI's Enterprise Value at -$38.3 million in Q1 2026, -$31.7 million in Q4 2025, and -$94.4 million in Q3 2025.
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Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Enterprise Value (Qtr) |
|---|---|---|---|---|---|
| 1 | Oculis Holding AG | 68,785.72 Bn | 68,785.72 Bn | - | -283.54 Mn |
| 2 | Nanobiotix | 1,895.57 Bn | 1,895.51 Bn | - | -61.40 Mn |
| 3 | BeOne Medicines | 471.35 Bn | 466.56 Bn | 1.35 Bn | -4.79 Bn |
| 4 | NuCana | 279.75 Bn | 279.75 Bn | - | -32.26 Mn |
| 5 | Vertex Pharmaceuticals | 120.24 Bn | 113.00 Bn | 2.59 Bn | -7.25 Bn |
| 6 | Regeneron Pharmaceuticals | 67.80 Bn | 59.04 Bn | 3.31 Bn | -8.75 Bn |
| 7 | Belite Bio | 62.51 Bn | 62.51 Bn | - | - |
| 8 | Argenx Se | 57.38 Bn | 57.38 Bn | 1.41 Bn | -5.18 Bn |
| 9 | Revolution Medicines | 37.78 Bn | 37.78 Bn | - | -1.91 Bn |
| 10 | Puma Biotechnology | 407.27 Mn | 368.99 Mn | 34.39 Mn | -38.28 Mn |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -38.28 Mn |
| Dec 31, 2025 | -31.73 Mn |
| Sep 30, 2025 | -94.39 Mn |
| Jun 30, 2025 | -56.75 Mn |
| Mar 31, 2025 | -93.17 Mn |
| Dec 31, 2024 | -100.97 Mn |
| Sep 30, 2024 | -96.73 Mn |
| Jun 30, 2024 | -96.83 Mn |
| Mar 31, 2024 | -107.16 Mn |
| Dec 31, 2023 | -95.94 Mn |
| Sep 30, 2023 | -85.03 Mn |
| Jun 30, 2023 | -74.44 Mn |
| Mar 31, 2023 | -71.22 Mn |
| Dec 31, 2022 | -81.07 Mn |
| Sep 30, 2022 | -77.96 Mn |
| Jun 30, 2022 | -60.75 Mn |
| Mar 31, 2022 | -63.91 Mn |
| Dec 31, 2021 | -71.98 Mn |
| Sep 30, 2021 | -87.54 Mn |
| Jun 30, 2021 | -108.93 Mn |