Puma Biotechnology (PBYI) EBT Margin (2017 - 2026)

Puma Biotechnology's (PBYI) quarterly EBT Margin came in at 7.65% in Q1 2026, down 1475.0% YoY from 0.56% in Q1 2025, and down 133.73% on a QoQ basis from 22.67% in Q4 2025.

Puma Biotechnology (PBYI) EBT Margin (2017 - 2026) Analysis & Trends

Puma Biotechnology (PBYI) has 10 years of EBT Margin data on file, last reported at 7.65% in Q1 2026.

  • Quarterly EBT Margin fell 1475.0% year-over-year to 7.65% in Q1 2026, while the trailing twelve-month figure through Mar 2026 was 12.8% (up 943.0% YoY) and the FY2025 annual result came in at 15.67%, changed N/A from the prior year.
  • EBT Margin retreated to 7.65% in Q1 2026, from 22.67% in the prior quarter.
  • In the past five years, EBT Margin ranged from a high of 25.59% in Q3 2024 to a low of 20.08% in Q4 2024.
  • A 5-year average of 4.39% and a median of 4.24% in 2023 frame the typical range for EBT Margin.
  • Annual changes were most pronounced in 2022 — EBT Margin soared 9601 bps — and 2024, when it plunged 3782 bps.
  • Tracing PBYI's EBT Margin over 5 years: stood at 6.06% in 2022, then surged by 393 bps to 17.74% in 2023, then slumped by 213 bps to 20.08% in 2024, then soared by 213 bps to 22.67% in 2025, then plunged by 134 bps to 7.65% in 2026.
  • The last three EBT Margin figures came in at 7.65% (Q1 2026), 22.67% (Q4 2025), and 16.97% (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBT Margin (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 41.75%
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 35.61%
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn 34.77%
4 Revolution Medicines 43.64 Bn 43.64 Bn - -
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 18.33%
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn -94.22%
7 Royalty Pharma 33.72 Bn 35.84 Bn - 12.09%
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 13.77%
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn -2.67%
10 Puma Biotechnology 451.24 Mn 357.33 Mn 44.03 Mn 14.59%

Historic Data

Download Data
DateValue
Jun 30, 2026 14.59%
Mar 31, 2026 -7.65%
Dec 31, 2025 22.67%
Sep 30, 2025 16.97%
Jun 30, 2025 11.76%
Mar 31, 2025 7.10%
Dec 31, 2024 -20.08%
Sep 30, 2024 25.59%
Jun 30, 2024 -8.82%
Mar 31, 2024 -10.50%
Dec 31, 2023 17.74%
Sep 30, 2023 10.71%
Jun 30, 2023 4.24%
Mar 31, 2023 2.93%
Dec 31, 2022 -6.06%
Sep 30, 2022 -0.51%
Jun 30, 2022 15.84%
Mar 31, 2022 -7.36%
Dec 31, 2021 8.01%
Sep 30, 2021 -96.52%