Alnylam Pharmaceuticals (ALNY) EBT Margin (2009 - 2026)

Alnylam Pharmaceuticals' (ALNY) quarterly EBT Margin came in at 13.77% in Q2 2026, up 1911.0% YoY from 0.68% in Q2 2025, and down 27.47% on a QoQ basis from 18.99% in Q1 2026.

Alnylam Pharmaceuticals (ALNY) EBT Margin (2009 - 2026) Analysis & Trends

Alnylam Pharmaceuticals (ALNY) has 18 years of EBT Margin data on file, last reported at 13.77% in Q2 2026.

  • Quarterly EBT Margin rose 1911.0% year-over-year to 13.77% in Q2 2026, while the trailing twelve-month figure through Jun 2026 was 15.95% (up 3420.0% YoY) and the FY2025 annual result came in at 8.7%, up 2549.0% from the prior year.
  • EBT Margin slipped to 13.77% in Q2 2026, from 18.99% in the prior quarter.
  • In the past five years, EBT Margin ranged from a high of 22.46% in Q3 2025 to a low of 153.59% in Q3 2022.
  • A 5-year average of 34.45% and a median of 17.28% in 2024 frame the typical range for EBT Margin.
  • Annual changes were most pronounced in 2022 — EBT Margin slumped 4474 bps — and 2023, when it soared 17367 bps.
  • Tracing ALNY's EBT Margin over 5 years: stood at 61.79% in 2022, then surged by 49 bps to 31.31% in 2023, then declined by 4 bps to 32.7% in 2024, then soared by 124 bps to 7.86% in 2025, then surged by 75 bps to 13.77% in 2026.
  • The last three EBT Margin figures came in at 13.77% (Q2 2026), 18.99% (Q1 2026), and 7.86% (Q4 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBT Margin (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 41.75%
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 35.61%
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn 34.77%
4 Revolution Medicines 43.64 Bn 43.64 Bn - -
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 18.33%
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn -94.22%
7 Royalty Pharma 33.72 Bn 35.84 Bn - 12.09%
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 13.77%
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn -2.67%
10 Roivant Sciences 26.16 Bn 26.85 Bn 1.16 Mn -20,427.46%

Historic Data

Download Data
DateValue
Jun 30, 2026 13.77%
Mar 31, 2026 18.99%
Dec 31, 2025 7.86%
Sep 30, 2025 22.46%
Jun 30, 2025 -4.57%
Mar 31, 2025 -0.40%
Dec 31, 2024 -32.70%
Sep 30, 2024 -21.69%
Jun 30, 2024 -1.69%
Mar 31, 2024 -12.86%
Dec 31, 2023 -31.31%
Sep 30, 2023 20.08%
Jun 30, 2023 -86.03%
Mar 31, 2023 -53.98%
Dec 31, 2022 -61.79%
Sep 30, 2022 -153.59%
Jun 30, 2022 -122.18%
Mar 31, 2022 -112.24%
Dec 31, 2021 -100.68%
Sep 30, 2021 -108.85%