Alnylam Pharmaceuticals (ALNY) EBT Margin (2009 - 2026)

Alnylam Pharmaceuticals (ALNY) posted EBT Margin of 18.99% for Q1 2026, up 141.51% on a QoQ basis from 7.86% in Q4 2025, and up 1939.0% year-over-year from 0.93% in Q1 2025.

Alnylam Pharmaceuticals (ALNY) EBT Margin (2009 - 2026) Analysis & Trends

Alnylam Pharmaceuticals' EBT Margin history runs 18 years deep, the most recent figure standing at 18.99% for Q1 2026.

  • Quarterly EBT Margin rose 1939.0% year-over-year to 18.99% in Q1 2026, while the trailing twelve-month figure through Mar 2026 was 12.9% (up 2637.0% YoY) and the FY2025 annual result came in at 8.7%, up 2549.0% from the prior year.
  • EBT Margin was 18.99% for Q1 2026 at Alnylam Pharmaceuticals, up from 7.86% in the prior quarter.
  • Across five years, EBT Margin topped out at 22.46% in Q3 2025 and bottomed at 153.59% in Q3 2022.
  • A 5-year average of 36.8% and a median of 21.69% in 2024 frame the typical range for EBT Margin.
  • Annual changes were most pronounced in 2022 — EBT Margin sank 4474 bps — and 2023, when it soared 17367 bps.
  • Alnylam Pharmaceuticals' EBT Margin stood at 61.79% in 2022, then jumped by 49 bps to 31.31% in 2023, then retreated by 4 bps to 32.7% in 2024, then surged by 124 bps to 7.86% in 2025, then jumped by 142 bps to 18.99% in 2026.
  • Business Quant data shows ALNY's EBT Margin at 18.99% in Q1 2026, 7.86% in Q4 2025, and 22.46% in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBT Margin (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 17.13%
4 NuCana 279.75 Bn 279.75 Bn - -
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 41.95%
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 23.05%
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn 34.77%
9 Revolution Medicines 37.78 Bn 37.78 Bn - -
10 Alnylam Pharmaceuticals 35.71 Bn 32.70 Bn 959.66 Mn 18.99%

Historic Data

Download Data
DateValue
Mar 31, 2026 18.99%
Dec 31, 2025 7.86%
Sep 30, 2025 22.46%
Jun 30, 2025 -4.57%
Mar 31, 2025 -0.40%
Dec 31, 2024 -32.70%
Sep 30, 2024 -21.69%
Jun 30, 2024 -1.69%
Mar 31, 2024 -12.86%
Dec 31, 2023 -31.31%
Sep 30, 2023 20.08%
Jun 30, 2023 -86.03%
Mar 31, 2023 -53.98%
Dec 31, 2022 -61.79%
Sep 30, 2022 -153.59%
Jun 30, 2022 -122.18%
Mar 31, 2022 -112.24%
Dec 31, 2021 -100.68%
Sep 30, 2021 -108.85%
Jun 30, 2021 -85.39%