Puma Biotechnology (PBYI) EBIT Margin (2017 - 2026)

Puma Biotechnology (PBYI) posted EBIT Margin of 8.54% for Q1 2026, down 137.68% on a QoQ basis from 22.67% in Q4 2025, and down 1720.0% year-over-year from 0.53% in Q1 2025.

Puma Biotechnology (PBYI) EBIT Margin (2017 - 2026) Analysis & Trends

Puma Biotechnology's EBIT Margin history runs 10 years deep, the most recent figure standing at 8.54% for Q1 2026.

  • Quarterly EBIT Margin fell 1720.0% year-over-year to 8.54% in Q1 2026, while the trailing twelve-month figure through Mar 2026 was 12.98% (down 303.0% YoY) and the FY2025 annual result came in at 16.33%, up 290.0% from the prior year.
  • EBIT Margin was 8.54% for Q1 2026 at Puma Biotechnology, down from 22.67% in the prior quarter.
  • Across five years, EBIT Margin topped out at 27.41% in Q3 2024 and bottomed at 8.54% in Q1 2026.
  • A 5-year average of 10.61% and a median of 11.43% in 2022 frame the typical range for EBIT Margin.
  • Peak annual rise in EBIT Margin reached 5142 bps in 2022, while the deepest fall reached 2216 bps in 2022.
  • Puma Biotechnology's EBIT Margin stood at 11.43% in 2022, then jumped by 79 bps to 20.5% in 2023, then rose by 10 bps to 22.62% in 2024, then climbed by 0 bps to 22.67% in 2025, then plunged by 138 bps to 8.54% in 2026.
  • Business Quant data shows PBYI's EBIT Margin at 8.54% in Q1 2026, 22.67% in Q4 2025, and 17.57% in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) EBIT Margin (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 16.51%
4 NuCana 279.75 Bn 279.75 Bn - -
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 38.10%
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 17.83%
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn 31.68%
9 Revolution Medicines 37.78 Bn 37.78 Bn - -
10 Puma Biotechnology 407.27 Mn 368.99 Mn 34.39 Mn -8.54%

Historic Data

Download Data
DateValue
Mar 31, 2026 -8.54%
Dec 31, 2025 22.67%
Sep 30, 2025 17.57%
Jun 30, 2025 12.66%
Mar 31, 2025 8.66%
Dec 31, 2024 22.62%
Sep 30, 2024 27.41%
Jun 30, 2024 -4.63%
Mar 31, 2024 -5.25%
Dec 31, 2023 20.50%
Sep 30, 2023 15.30%
Jun 30, 2023 8.96%
Mar 31, 2023 8.27%
Dec 31, 2022 11.43%
Sep 30, 2022 4.19%
Jun 30, 2022 20.26%
Mar 31, 2022 -1.63%
Dec 31, 2021 12.34%
Sep 30, 2021 -19.36%
Jun 30, 2021 -31.16%