Growth Metrics

Opko Health (OPK) Gross Margin (2016 - 2025)

Opko Health (OPK) has disclosed Gross Margin for 16 consecutive years, with 43.13% as the latest value for Q4 2025.

  • For the quarter ending Q4 2025, Gross Margin fell 297.0% year-over-year to 43.13%, compared with a TTM value of 33.93% through Dec 2025, up 2170.0%, and an annual FY2025 reading of 33.93%, up 329.0% over the prior year.
  • Gross Margin was 43.13% for Q4 2025 at Opko Health, up from 32.9% in the prior quarter.
  • Across five years, Gross Margin topped out at 185.32% in Q3 2023 and bottomed at 4462.36% in Q1 2023.
  • Average Gross Margin over 5 years is 290.36%, with a median of 35.32% recorded in 2025.
  • The sharpest move saw Gross Margin tumbled -455547bps in 2023, then skyrocketed 448658bps in 2024.
  • Year by year, Gross Margin stood at 94.75% in 2021, then soared by 90bps to 179.74% in 2022, then crashed by -107bps to 12.87% in 2023, then soared by 458bps to 46.1% in 2024, then dropped by -6bps to 43.13% in 2025.
  • Business Quant data shows Gross Margin for OPK at 43.13% in Q4 2025, 32.9% in Q3 2025, and 31.5% in Q2 2025.