Opko Health (OPK) Gross Margin (2010 - 2026)
Opko Health (OPK) posted Gross Margin of 48.92% for Q2 2026, up 17.41 percentage points from 31.50% a year earlier and up 12.08 percentage points from the prior quarter.
Opko Health (OPK) Gross Margin (2010 - 2026) Analysis & Trends
For the trailing twelve months through Jun 30, 2026, Gross Margin at Opko Health was 40.77%, up 8.12 percentage points year-over-year; for FY2025, it came in at 33.93%, up 3.29 percentage points from FY2024.
- Annual Gross Margin shows a five-year change of -8.67 percentage points (FY2020 to FY2025).
- In prior years, Opko Health's Gross Margin was 30.64% in FY2024 (-6.20 pp), 36.84% in FY2023 (+8.14 pp), 28.70% in FY2022 (-9.19 pp) and 37.90% in FY2021 (-4.71 pp).
- The Q2 2026 figure stands as the highest quarterly Gross Margin since Q4 2021.
- On a year-over-year basis, Gross Margin increased in six of the last eight quarters, with an average year-over-year change of +7.24 percentage points.
- The strongest year-over-year quarter for Gross Margin in the past five years was Q4 2024, with a gain of 21.52 percentage points; the weakest was Q4 2022, with a drop of 19.51 percentage points.
- According to Business Quant data, Gross Margin for the three prior quarters was 36.84% (Q1 2026), 43.13% (Q4 2025) and 32.90% (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | Gross Margin (Qtr) |
|---|---|---|---|---|---|
| 1 | Eli Lilly | 1,146.94 Bn | 1,115.53 Bn | 19.71 Bn | 85.78% |
| 2 | Johnson & Johnson | 624.96 Bn | 543.49 Bn | 17.26 Bn | 68.19% |
| 3 | AbbVie | 510.15 Bn | 483.27 Bn | 12.70 Bn | 74.74% |
| 4 | Merck | 366.13 Bn | 320.51 Bn | 12.21 Bn | 73.54% |
| 5 | Novartis Ag | 297.75 Bn | 261.74 Bn | 11.24 Bn | 78.02% |
| 6 | Astrazeneca | 261.93 Bn | 235.62 Bn | 12.86 Bn | 83.60% |
| 7 | Amgen | 236.51 Bn | 191.91 Bn | 7.24 Bn | 72.04% |
| 8 | Gilead Sciences | 194.27 Bn | 168.47 Bn | 6.22 Bn | 79.76% |
| 9 | Pfizer | 171.74 Bn | 118.39 Bn | 10.94 Bn | 72.78% |
| 10 | Opko Health | 1.26 Bn | -169.39 Mn | 80.02 Mn | 48.92% |
Historic Data
| Date | Value |
|---|---|
| Jun 30, 2026 | 48.92% |
| Mar 31, 2026 | 36.84% |
| Dec 31, 2025 | 43.13% |
| Sep 30, 2025 | 32.90% |
| Jun 30, 2025 | 31.50% |
| Mar 31, 2025 | 28.42% |
| Dec 31, 2024 | 46.10% |
| Sep 30, 2024 | 23.11% |
| Jun 30, 2024 | 28.35% |
| Mar 31, 2024 | 24.22% |
| Dec 31, 2023 | 24.58% |
| Sep 30, 2023 | 26.70% |
| Jun 30, 2023 | 47.65% |
| Mar 31, 2023 | 41.78% |
| Dec 31, 2022 | 30.21% |
| Sep 30, 2022 | 17.41% |
| Jun 30, 2022 | 37.30% |
| Mar 31, 2022 | 25.92% |
| Dec 31, 2021 | 49.72% |
| Sep 30, 2021 | 36.77% |
Opko Health Gross Margin API
Pull this series into your own models, spreadsheets and apps with the Business Quant
Historical Metrics API. The request below matches the chart above — change the
frequency, period or values and it follows. Swap YOUR_API_KEY for your own key.
https://data.businessquant.com/historic?slug=gross-margin&ticker=OPK&period=max&api_key=YOUR_API_KEY
import requests
url = "https://data.businessquant.com/historic"
params = {"slug": "gross-margin", "ticker": "OPK", "period": "max", "api_key": "YOUR_API_KEY"}
data = requests.get(url, params=params).json()
const res = await fetch("https://data.businessquant.com/historic?slug=gross-margin&ticker=OPK&period=max&api_key=YOUR_API_KEY");
const data = await res.json();