OnKure Therapeutics OKUR
NASDAQ OKUR
$3.93 -0.15 (-3.68%)
At close: Aug 20, 2026 · 4:00 PM EDT

OnKure Therapeutics (OKUR) Return on Capital Employed (2021 - 2026)

OnKure Therapeutics' (OKUR) quarterly Return on Capital Employed came in at 53.04% in Q1 2026, up 938.0% YoY from 5.11% in Q1 2025, and up 48.14% on a QoQ basis from 102.27% in Q4 2025.

OnKure Therapeutics (OKUR) Return on Capital Employed (2021 - 2026) Analysis & Trends

OnKure Therapeutics (OKUR) has 6 years of Return on Capital Employed data on file, last reported at 53.04% in Q1 2026.

  • Quarterly Return on Capital Employed rose 938.0% year-over-year to 53.04% in Q1 2026, while the trailing twelve-month figure through Mar 2026 was 53.04% (up 938.0% YoY) and the FY2025 annual result came in at 76.22%, up 772.0% from the prior year.
  • Return on Capital Employed grew to 53.04% in Q1 2026, from 102.27% in the prior quarter.
  • In the past five years, Return on Capital Employed ranged from a high of 19.45% in Q3 2024 to a low of 102.27% in Q4 2025.
  • A 5-year average of 55.26% and a median of 53.41% in 2024 frame the typical range for Return on Capital Employed.
  • Annual changes were most pronounced in 2024 — Return on Capital Employed soared 3834 bps — and 2025, when it tumbled 7279 bps.
  • Tracing OKUR's Return on Capital Employed over 5 years: stood at 49.76% in 2022, then rose by 2 bps to 48.74% in 2023, then plunged by 30 bps to 63.43% in 2024, then tumbled by 61 bps to 102.27% in 2025, then surged by 48 bps to 53.04% in 2026.
  • The last three Return on Capital Employed figures came in at 53.04% (Q1 2026), 102.27% (Q4 2025), and 92.24% (Q3 2025), per Business Quant data.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROCE (Qtr)
1 Vertex Pharmaceuticals 137.11 Bn 129.26 Bn 2.84 Bn 20.76%
2 Regeneron Pharmaceuticals 84.98 Bn 76.99 Bn 3.93 Bn 10.74%
3 Argenx Se 64.52 Bn 59.33 Bn 1.37 Bn -
4 Moderna 53.23 Bn 48.09 Bn 52.00 Mn -38.20%
5 BeOne Medicines 41.23 Bn 36.14 Bn 1.53 Bn 13.68%
6 Alnylam Pharmaceuticals 30.65 Bn 27.34 Bn 992.69 Mn 26.09%
7 Insmed 27.15 Bn 25.99 Bn 358.27 Mn -50.93%
8 Royalty Pharma 26.98 Bn 26.14 Bn - 7.88%
9 BioNTech SE 26.78 Bn 8.39 Bn 668.28 Mn -6.85%
10 OnKure Therapeutics 196.98 Mn 20.60 Mn - -34.07%

Historic Data

Download Data
DateValue
Jun 30, 2026 -34.07%
Mar 31, 2026 -53.04%
Dec 31, 2025 -102.27%
Sep 30, 2025 -92.24%
Jun 30, 2025 -74.42%
Mar 31, 2025 -62.42%
Dec 31, 2024 -63.43%
Sep 30, 2024 -19.45%
Jun 30, 2024 -29.81%
Mar 31, 2024 -53.41%
Dec 31, 2023 -48.74%
Sep 30, 2023 -57.79%
Jun 30, 2023 -59.76%
Mar 31, 2023 -61.21%
Dec 31, 2022 -49.76%
Sep 30, 2022 -42.08%
Jun 30, 2022 -37.36%
Mar 31, 2022 -32.28%
Dec 31, 2021 -26.15%
Sep 30, 2021 -22.05%