Orchestra BioMed Holdings (OBIO) Return on Sales (2022 - 2026)

Orchestra BioMed Holdings' (OBIO) quarterly Return on Sales came in at 2.25% in Q1 2026, down 203.0% year-on-year from 2.18% in Q1 2025, and down 108933.57% on a QoQ basis from 0.0% in Q4 2025.

Orchestra BioMed Holdings (OBIO) Return on Sales (2022 - 2026) Analysis & Trends

Orchestra BioMed Holdings (OBIO) has 5 years of Return on Sales data on file, last reported at 2.25% in Q1 2026.

  • On a quarterly basis, Return on Sales fell 203.0% year-over-year to 2.25% in Q1 2026; TTM through Mar 2026 was 0.02%, a 25.0% increase from a year earlier, with the FY2025 full-year figure at 0.05%, up 55.0% from the prior year.
  • Return on Sales for Q1 2026 stood at 2.25%, down from 0.0% in the prior quarter.
  • Over the last five years, Return on Sales for OBIO reached as high as 0.0% in Q4 2025 and fell as low as 2.25% in Q1 2026.
  • Historically, Return on Sales has averaged 0.36% across 5 years, with a median of 0.22% in 2025.
  • Across the five-year window, Return on Sales jumped 64 bps in 2025 and slumped 203 bps in 2026, its largest moves.
  • Year by year, Return on Sales stood at 0.09% in 2022, then sank by 406 bps to 0.47% in 2023, then plunged by 37 bps to 0.64% in 2024, then jumped by 100 bps to 0.0% in 2025, then tumbled by 108934 bps to 2.25% in 2026.
  • Per Business Quant data, the three most recent Return on Sales figures were 2.25% in Q1 2026, 0.0% in Q4 2025, and 0.24% in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROS (Qtr)
1 Oculis Holding AG 68,785.72 Bn 68,785.72 Bn - -
2 Nanobiotix 1,895.57 Bn 1,895.51 Bn - -
3 BeOne Medicines 471.35 Bn 466.56 Bn 1.35 Bn 0.00%
4 NuCana 279.75 Bn 279.75 Bn - -
5 Vertex Pharmaceuticals 120.24 Bn 113.00 Bn 2.59 Bn 0.00%
6 Regeneron Pharmaceuticals 67.80 Bn 59.04 Bn 3.31 Bn 0.00%
7 Belite Bio 62.51 Bn 62.51 Bn - -
8 Argenx Se 57.38 Bn 57.38 Bn 1.41 Bn 0.00%
9 Revolution Medicines 37.78 Bn 37.78 Bn - -
10 Orchestra BioMed Holdings 228.31 Mn 143.68 Mn 78,000.00 -2.25%

Historic Data

Download Data
DateValue
Mar 31, 2026 -2.25%
Dec 31, 2025 0.00%
Sep 30, 2025 -0.24%
Jun 30, 2025 -0.26%
Mar 31, 2025 -0.22%
Dec 31, 2024 -0.64%
Sep 30, 2024 -0.18%
Jun 30, 2024 -0.32%
Mar 31, 2024 -0.25%
Dec 31, 2023 -0.47%
Sep 30, 2023 -0.53%
Jun 30, 2023 -0.19%
Mar 31, 2023 -0.10%
Dec 31, 2022 -0.09%
Sep 30, 2022 -0.09%
Jun 30, 2022 -0.20%
Mar 31, 2022 -0.06%