Orchestra BioMed Holdings (OBIO) Return on Sales (2022 - 2026)

Orchestra BioMed Holdings (OBIO) posted quarterly Return on Sales of 2.25% for Q1 2026, down 203.0% year-over-year from 2.18% in Q1 2025, and down 108933.57% quarter-over-quarter from 0.0% in Q4 2025.

Orchestra BioMed Holdings (OBIO) Return on Sales (2022 - 2026) Analysis & Trends

Orchestra BioMed Holdings (OBIO) has reported Return on Sales for 5 consecutive years, with 2.25% the latest figure, recorded in Q1 2026.

  • In Q1 2026, Return on Sales fell 203.0% year-over-year to 2.25%; the TTM figure through Mar 2026 stood at 0.02% (up 25.0% YoY), while the FY2025 annual figure was 0.05%, up 55.0% from the prior year.
  • Return on Sales retreated to 2.25% in Q1 2026 per OBIO's latest filing, from 0.0% in the prior quarter.
  • Across five years, Return on Sales topped out at 0.0% in Q4 2025 and bottomed at 2.25% in Q1 2026.
  • Historically, Return on Sales has averaged 0.36% across 5 years, with a median of 0.22% in 2025.
  • Annual changes were most pronounced in 2025 — Return on Sales soared 64 bps — and 2026, when it plunged 203 bps.
  • Orchestra BioMed Holdings' Return on Sales stood at 0.09% in 2022, then slumped by 421 bps to 0.48% in 2023, then tumbled by 34 bps to 0.64% in 2024, then surged by 100 bps to 0.0% in 2025, then tumbled by 108934 bps to 2.25% in 2026.
  • Business Quant data shows OBIO's Return on Sales at 2.25% in Q1 2026, 0.0% in Q4 2025, and 0.24% in Q3 2025.

Peer Comparison

# Company Market Cap Enterprise Value Gross Profit (Qtr) ROS (Qtr)
1 Vertex Pharmaceuticals 128.13 Bn 120.28 Bn 2.84 Bn 0.00%
2 Regeneron Pharmaceuticals 112.33 Bn 104.33 Bn 3.93 Bn 0.00%
3 Argenx Se 53.24 Bn 48.05 Bn 1.41 Bn 0.00%
4 Revolution Medicines 43.64 Bn 43.64 Bn - -
5 BeOne Medicines 39.27 Bn 34.17 Bn 1.53 Bn 0.00%
6 MindWalk Holdings 35.32 Bn 35.31 Bn 1.82 Bn 0.00%
7 Royalty Pharma 33.72 Bn 35.84 Bn - 0.00%
8 Alnylam Pharmaceuticals 30.58 Bn 27.27 Bn 992.69 Mn 0.00%
9 Insmed 27.01 Bn 25.85 Bn 358.27 Mn 0.00%
10 Orchestra BioMed Holdings 265.06 Mn 80.63 Mn 63,000.00 -2.87%

Historic Data

Download Data
DateValue
Jun 30, 2026 -2.87%
Mar 31, 2026 -2.25%
Dec 31, 2025 0.00%
Sep 30, 2025 -0.24%
Jun 30, 2025 -0.26%
Mar 31, 2025 -0.22%
Dec 31, 2024 -0.64%
Sep 30, 2024 -0.18%
Jun 30, 2024 -0.32%
Mar 31, 2024 -0.25%
Dec 31, 2023 -0.48%
Sep 30, 2023 -0.53%
Jun 30, 2023 -0.19%
Mar 31, 2023 -0.10%
Dec 31, 2022 -0.09%
Sep 30, 2022 -0.09%
Jun 30, 2022 -0.20%
Mar 31, 2022 -0.06%