Orchestra BioMed Holdings (OBIO) Return on Sales (2022 - 2026)
Orchestra BioMed Holdings (OBIO) reported Return on Sales of 2.08% for Q1 2026, down 187.0% year-over-year from 2.39% in Q1 2025, and down 107519.7% on a QoQ basis from 0.0% in Q4 2025.
Orchestra BioMed Holdings (OBIO) has 5 years of Return on Sales data on file, last reported at 2.08% in Q1 2026.
- Quarterly Return on Sales fell 187.0% year-over-year to 2.08% in Q1 2026, while the trailing twelve-month figure through Mar 2026 was 0.02% (up 21.0% YoY) and the FY2025 annual result came in at 0.02%, up 22.0% from the prior year.
- Return on Sales fell to 2.08% in Q1 2026 per OBIO's latest filing, from 0.0% in the prior quarter.
- Across five years, Return on Sales topped out at 0.0% in Q4 2025 and bottomed at 2.08% in Q1 2026.
- The 5-year median for Return on Sales is 0.21% (2024), against an average of 0.32%.
- The widest annual swing landed in 2025, when Return on Sales jumped 64 bps; it then tumbled 187 bps in 2026.
- Tracing OBIO's Return on Sales over 5 years: stood at 0.09% in 2022, then tumbled by 387 bps to 0.43% in 2023, then sank by 47 bps to 0.64% in 2024, then soared by 100 bps to 0.0% in 2025, then slumped by 107520 bps to 2.08% in 2026.
- Per Business Quant, the three latest OBIO Return on Sales figures stand at 2.08% (Q1 2026), 0.0% (Q4 2025), and 0.24% (Q3 2025).
Peer Comparison
| # | Company | Market Cap | Enterprise Value | Gross Profit (Qtr) | ROS (Qtr) |
|---|---|---|---|---|---|
| 1 | Quantum Biopharma | 1,216,509.61 Bn | 1,216,509.61 Bn | - | - |
| 2 | Alterity Therapeutics | 764,224.41 Bn | 764,224.38 Bn | - | - |
| 3 | Legend Biotech | 2,716.00 Bn | 2,715.71 Bn | 242.10 Mn | 0.00% |
| 4 | Nanobiotix | 2,248.83 Bn | 2,248.77 Bn | - | - |
| 5 | Akari Therapeutics | 1,951.18 Bn | 1,951.17 Bn | - | - |
| 6 | Vertex Pharmaceuticals | 113.69 Bn | 106.44 Bn | 2.59 Bn | 0.00% |
| 7 | Evaxion A | 64.16 Bn | 64.14 Bn | - | 0.00% |
| 8 | Regeneron Pharmaceuticals | 63.94 Bn | 55.18 Bn | 3.31 Bn | 0.00% |
| 9 | Alnylam Pharmaceuticals | 40.13 Bn | 37.12 Bn | 959.66 Mn | 0.00% |
| 10 | Orchestra BioMed Holdings | 245.24 Mn | 255.02 Mn | 78,000.00 | -2.08% |
Historic Data
Download Data| Date | Value |
|---|---|
| Mar 31, 2026 | -2.08% |
| Dec 31, 2025 | 0.00% |
| Sep 30, 2025 | -0.24% |
| Jun 30, 2025 | -0.23% |
| Mar 31, 2025 | -0.22% |
| Dec 31, 2024 | -0.64% |
| Sep 30, 2024 | -0.16% |
| Jun 30, 2024 | -0.21% |
| Mar 31, 2024 | -0.22% |
| Dec 31, 2023 | -0.43% |
| Sep 30, 2023 | -0.32% |
| Jun 30, 2023 | -0.14% |
| Mar 31, 2023 | -0.10% |
| Dec 31, 2022 | -0.09% |
| Sep 30, 2022 | -0.09% |
| Jun 30, 2022 | -0.19% |
| Mar 31, 2022 | -0.06% |