A total of 35 institutions have reported a stake in Orchestra BioMed Holdings, Inc. (NASDAQ:OBIO) as of December 2025, according to recent 13F filings with the SEC.
| Owner Name | Date | Shares Held | Change (QoQ) | Change (%) | Value (USD) |
|---|---|---|---|---|---|
| VANGUARD GROUP INC | 31 Dec, 2025 | 1,604,556 | 122,681 | 8.28% | $6,658,907.00 |
| Alyeska Investment Group, L.P. | 31 Dec, 2025 | 1,000,000 | -365,482 | -26.77% | $4,150,000.00 |
| BlackRock, Inc. | 31 Dec, 2025 | 630,901 | -33,432 | -5.03% | $2,618,239.00 |
| Affinity Asset Advisors, LLC | 31 Dec, 2025 | 572,804 | -154,468 | -21.24% | $2,377,137.00 |
| GEODE CAPITAL MANAGEMENT, LLC | 31 Dec, 2025 | 473,363 | 86,564 | 22.38% | $1,965,479.00 |
| CHARLES SCHWAB INVESTMENT MANAGEMENT INC | 31 Dec, 2025 | 263,788 | 83,349 | 46.19% | $1,094,720.00 |
| Knott David M Jr | 31 Dec, 2025 | 250,000 | 55,000 | 28.21% | $1,037,500.00 |
| JANE STREET GROUP, LLC | 31 Dec, 2025 | 187,665 | 122,141 | 186.41% | $778,809.00 |
| MARSHALL WACE, LLP | 31 Dec, 2025 | 171,681 | 171,681 | 0.00% | $712,476.00 |
| STATE STREET CORP | 31 Dec, 2025 | 159,033 | 58,300 | 57.88% | $659,987.00 |
| RENAISSANCE TECHNOLOGIES LLC | 31 Dec, 2025 | 151,300 | -229,208 | -60.24% | $627,895.00 |
| GOLDMAN SACHS GROUP INC | 31 Dec, 2025 | 134,073 | 110,443 | 467.38% | $556,403.00 |
| BARCLAYS PLC | 31 Dec, 2025 | 94,517 | 94,516 | 9,451,600.00% | $392,246.00 |
| IFP Advisors, Inc | 31 Dec, 2025 | 86,698 | 0 | 0.00% | $359,797.00 |
| MORGAN STANLEY | 31 Dec, 2025 | 81,851 | 71,528 | 692.90% | $339,682.00 |
| OMERS ADMINISTRATION Corp | 31 Dec, 2025 | 67,100 | 67,100 | 0.00% | $278,465.00 |
| Holos Integrated Wealth LLC | 31 Dec, 2025 | 51,595 | 0 | 0.00% | $222,374.00 |
| Hudson Bay Capital Management LP | 31 Dec, 2025 | 49,425 | 49,425 | 0.00% | $205,114.00 |
| TD ASSET MANAGEMENT INC | 31 Dec, 2025 | 45,692 | -46,986 | -50.70% | $189,622.00 |
| Squarepoint Ops LLC | 31 Dec, 2025 | 44,343 | 44,343 | 0.00% | $184,023.00 |